I had lipid panels when I was on it. They kept getting worse,and worse....to the point the wanted me to stop taking it. It did wonders for my teen acne, I use to breakout alot....not anymore. I understand what your saying though, that with monitored care things are safe. It made my skin sooooo,soooo dry that my lips were always cracked,and painfull. This is not a fun drug to take!