PowerFULL Human and Healthy test subjects-Conclusively effective

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datBtrue said:
Thanks for posting these studies...it is appreciated.

Two quick questions:

  1. How long do you think that it is possible to heep GH elevated w/ L-Dopa or Powerfull? Is this a short term effect or do you think w/ consistent dosing it will have a sustained propensity to keep GH elevated for say a three month period?
  2. Forget the science, just based on your own opinion do you think that GH can be spiked at a particular time, say post workout w/ a large dose of powerfull? or are we talking about a slower cumulative buildup effect?
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1) It is hard to say. If you review the studies, the L-Dopa did raise it far above basal levels for the given period. However, none of them were long-term enough to determine if the suggested increase was durational. I will investigate the MOA's further and try and have a more in-depth answer.

2) It is a spike, however post-workout would be counterproductive to the product (insulin release)
 
datBtrue said:
Thanks for posting these studies...it is appreciated.

Two quick questions:

  1. How long do you think that it is possible to heep GH elevated w/ L-Dopa or Powerfull? Is this a short term effect or do you think w/ consistent dosing it will have a sustained propensity to keep GH elevated for say a three month period?
  2. Forget the science, just based on your own opinion do you think that GH can be spiked at a particular time, say post workout w/ a large dose of powerfull? or are we talking about a slower cumulative buildup effect?
Click to expand...


1. The increase in research was 90-120 minutes than returned to baseline.

2. There is not a cumulative build up. HGH increases and returns to normal. The increase in HGH will have a cumulative effect on recovery.

The best way to use PowerFULL is:
1. 30 minutes before fasted Morning Cardio
2. Before sleep
3. 10-30 minutes before workout (based off the research that natural l-dop reaches peak concentrations in 32 minutes so HGH).
4. 1 hour after eating a meal.

Glucose (insulin) will kill the HGH reseonse and glucose metabolism of a meal is 1 hour.

For example, if you are drinking carbohydrates during workouts then do not use Powerfull.

If you are using carbohydrates 1 hour pre workout, you should take PowerFULL about 10 minutes before workout.

If you are using PowerFULL between meals, you should dose it 1 hour after the meal and this will allow HGH to peak inbetween meals and return to baseline just in time for your next meal.
 
USPLabs said:
1. The increase in research was 90-120 minutes than returned to baseline.

2. There is not a cumulative build up. HGH increases and returns to normal. The increase in HGH will have a cumulative effect on recovery.

The best way to use PowerFULL is:
1. 30 minutes before fasted Morning Cardio
2. Before sleep
3. 10-30 minutes before workout (based off the research that natural l-dop reaches peak concentrations in 32 minutes so HGH).
4. 1 hour after eating a meal.

Glucose (insulin) will kill the HGH reseonse and glucose metabolism of a meal is 1 hour.

For example, if you are drinking carbohydrates during workouts then do not use Powerfull.

If you are using carbohydrates 1 hour pre workout, you should take PowerFULL about 10 minutes before workout.

If you are using PowerFULL between meals, you should dose it 1 hour after the meal and this will allow HGH to peak inbetween meals and return to baseline just in time for your next meal.
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Great information here. Thanks for taking the time to thoroughly explain how to maxamize the GH release... this will be a huge benefit for me in PCT and thereafter...

Thanks bro.
 
USPLabs said:
He is also a competitor at Recomp Performance Nutrition Co-President.

Maybe, He can post some Human studies on his products.
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I suppose I should have identified myself but it is difficult here without being able to have signatures. We have no GH product and no products that compete and we will never have a GH product.

There is some human data on all of our ingredients except raspberry ketones and salvia. Even Havoc, though unmethylated obviously. But I don't think you can say the same either. That is beside the point though.

I am also working on a very in depth paper on PPARs that will integrate many related pathways down to each gene and different polymorphisms. I don't just want to make claims but advance the PPAR field for sports nutrition. You are of course welcome to challenge anything I write, it is healthy for everyone.

Anyway I hope I can still ask questions being affiliated since the functions of the human body is my obsession.
 
^ Derave W, Ozdemir MS, Harris R, Pottier A, Reyngoudt H, Koppo K, Wise JA, Achten E. (Aug 9). "Beta-alanine supplementation augments muscle carnosine content and attenuates fatigue during repeated isokinetic contraction bouts in trained sprinters". J Appl Physiol. PMID 17690198.
^ Hill CA, Harris RC, Kim HJ, Harris BD, Sale C, Boobis LH, Kim CK, Wise JA. (2007). "Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity". Amino Acids 32 (2): 225-33. PMID 16868650.
Dunnett M & Harris RC: Influence of oral beta-alanine and L-Histidine supplementation on the carnosine content of gluteus medius. Equine Vet J 30: 499 - 504, 1999
Harris, R. FASEB. Effect of Combined Beta-Alanine and Creatine Monohydrate Supplementation on Exercise Performance
Hoffman J, Ratamess N, Kang J, Mangine G, Faigenbaum A, Stout J. (2006) Effect of Creatine and ß-Alanine Supplementation on Performance and Endocrine Responses in Strength/Power Athletes. IJSNEM, 16(4).
Zoeller RF, Stout JR, O’kroy JA, Torok DJ, Mielke M.(2006)
Effects of 28 days of beta-alanine and creatine monohydrate supplementation on aerobic power, ventilatory and lactate thresholds, and time to exhaustion. Amino Acids, 1-6
Harris RC, Tallon MJ Dunnett M, Boobis L, Coakley J, Kim HJ, Fallowfield JL, Hill CA, Sale C, Wise JA (2006) The absorption of orally supplied §-alanine and its effect on muscle carnosine synthesis in human vastus lateralis. Amino Acids, March.
Harris RC, Ponte J, Sale C, Jones GA, Kim HJ, Wise JA. Effect of 14 and 28 days B-Alanine(Carnosyn™) supplementation on isometric endurance of the knee extensors.Univeristy of Chichester, Chichester UK; Korea National Sport Univeristy, Seoul Korea. Poster Presentation
Harris RC, Marlin DJ, Dunnett M, Snow DH, Hultman E ((1990) Muscle buffering capacity & dipeptide content in the thoroughbred horse, greyhound dog & man. Comparative Biochem Physiol 97A: 249-251
Harris, R C, Hill,C; JA (2003) Effect of combined beta-alanine and creatine monohydrate supplementaion on exercise performance. Medicine & Science in Sports & Exercise: Volume 35(5) Supplement 1 May 2003 S21
Hill CA, Harris RC, Kim HJ, Harris BD, Sale C, Boobis LH, Kim CK, Wise JA (2006) Influence of b- alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity Amino Acids.
Hill C. A., R. C. Harris, H. J. Kim, L. Boobis, C. Sale, J. A. Wise. “The effect of beta-alanine and creatine monohydrate supplementation on muscle composition and exercise performance.” (Presented at the American College of Sports Medicine Annual conference, 2005, Nashville.)
Kim HJ, Kim CK, Lee YW, Harris RC, Sale C, Harris DB, and Wise JA (2006) The effect of a supplement containing β-alanine on muscle carnosine synthesis and exercise capacity, during 12 wk combined endurance and weight training. J. Inter. Soc. Sports Nutr. 3(1): S9
Stout JR, Cramer JT, Mielke M, O’Kroy J, Torok D, and Zoeller RF (2006) Effects of 28 days of beta-alanine and creatine monohydrate supplementation on the physical working capacity at neuromuscular fatigue threshold J Strength Cond Res (in press)
Stout JR, Cramer JT, Zoeller RF, Torok D, Costa P, Hoffman JR (2006) Effects of beta-alanine supplementation on the onset of neuromuscular fatigue and ventilatory threshold in women. Amino Acids. Nov 30


some beta alanine studies. I don't care to look each one up, but it seems quite a few are on humans.
 
Mulletsoldier said:
1) It is hard to say. If you review the studies, the L-Dopa did raise it far above basal levels for the given period. However, none of them were long-term enough to determine if the suggested increase was durational. I will investigate the MOA's further and try and have a more in-depth answer.

2) It is a spike, however post-workout would be counterproductive to the product (insulin release)
Click to expand...


Is #2 from some data or more speculative? Beyond the one study that showed damping of the hgh at 100g of dextrose.

The reason I ask is that there is some evidence that the release of insulin while hGH levels are high is what causes IGF-1 to apppear or that there is at least some causal relationship there. So I wonder if that may not be a really good time to take it to get igf-1 boost.

Is the molecular weight of l-dopa low enough to go as a transdermal? and what is the % of the extract?
 
jmh80 said:
I just want to say I loves me some Powerfull. :thumbsup:
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On an equally anecdotal note, I'm what has been referred to as a PowerFull "non-responder." I used 2 or 3 bottles of the original formula (strictly adhering to the instructions), without any noticeable effects whatsoever. It might as well have been sugar pills.
I'm no scientist, and I have no idea why a supplement can be so effective for some, yet completely empty for others. But everytime I poo-poo PowerFull, I also point out that my favorite supp of all time is Cissus. So I'm a big fan of USP Labs, but PowerFull simply doesn't work for me. :confused:
 
That sucks ImJ. It worked great for me.

I've not tried the bulk p'full - will do that soon.

Just goes to show everyone doesn't respond the same. Hell - Cissus didn't help my knees much at all.
 
I've been using bulk powerfull everyday for the past 2 years or so at least, maybe longer, can't remember now. Only time I don't use it is when I'm on. And I'm on a 5 month test cycle atm and will be mega-dosing PF during PCT. It really works great for me and you can't beat the price. Even at only 1TBSP./day, just once/day, I notice the benefits from it.

Cissus also works great for me but haven't used it in a long while, no real reason why, just haven't picked any up in awhile, I also noticed anabolic ben with it as well, in addition to the anti-inflam ben. Will be using again during PCT as well.
Camph is also a gonna be included.

I trust that USP knows they're stuff as in their extraction processes, etc... put it this way, I've used their prooducts, they give me great results, they are pretty much the best-priced supps out there, esp when taking into consideration the effectivenss of the products, so why fix what ain't broke and buy from somewhere else? I give 'em 3 thumbs up!! The third thumb being from the PF of course. :D
 
P.S. for you guys that say you haven't had success w/ PF. When I first tried it, when it first came out, I noticed a big difference at first in terms of results, but then they tended to wear off after the first week or so...well, I noticed that when I stayed on it, the benefits became more of a cumulative effect and IMO is best used long term and not for a month and then stopping. These are staple supps for a reason, if you're gonna use them, I'd give them some more time to produce results...same with cissus, camph, etc...
 
Can someone please link me to bulk powerfull?

Since reaching my 30's I have always had some positive results for secretagogues, so im intersted to see if I have even a gtreater response from powerfull!

The main real world positve I notice from secretagogues is a instant 1/2 mile increase in my morning jog, so hopefully I notice a much bigger difference overall from powerfull.
seems all the gh increasers work better for the over 30 crowd , I wonder if powerfull is in that same boat?
 
I respond very well to maylasian tongat ali, Do you think other test boosters such as tongkat ali, nettle ect... would be overkill with powerfull or would it work syngeristally with the test booster in powerfull?

Until I hear otherwise Im guessing that multiple test boosters would be a waste of money since theres probally a limit to how much the leyding cells can be forced into produce more testosterone.
 
I don't think it would be redundant or counterproductive. With other products you are mediating Test production through other pathways. If you chose a product which does so in the exact same manner than PF, then yes, that may be redundant as you may exhaust the same pathway.

ActivaTE would be a great stack with Powerfull.
 
Since powerfull should be taken away from carbs, p-slin and anabolic pump would not be good supps to stack with powerfull. correct?
 
Whats the optimum waiting period to consume carbs after taking the powerfull 1 hr for complex , 2 hrs for fast acting carbs?

The hgh rises and falls in 2 hrs from powerfull , correct?
 
USPLabs said:
1. The increase in research was 90-120 minutes than returned to baseline.

2. There is not a cumulative build up. HGH increases and returns to normal. The increase in HGH will have a cumulative effect on recovery.

The best way to use PowerFULL is:
1. 30 minutes before fasted Morning Cardio
2. Before sleep
3. 10-30 minutes before workout (based off the research that natural l-dop reaches peak concentrations in 32 minutes so HGH).
4. 1 hour after eating a meal.

Glucose (insulin) will kill the HGH reseonse and glucose metabolism of a meal is 1 hour.

For example, if you are drinking carbohydrates during workouts then do not use Powerfull.

If you are using carbohydrates 1 hour pre workout, you should take PowerFULL about 10 minutes before workout.

If you are using PowerFULL between meals, you should dose it 1 hour after the meal and this will allow HGH to peak inbetween meals and return to baseline just in time for your next meal.
Click to expand...

Can you tell me how to properly stack p slin, anabolic pump and powerfull, its a bit confusing since the slin and ap need carbs to work properly while carbs shoot hgh down.


How many hrs before bedtime should your last carb meal be so powerfull has full efect?

How many caps of p slin and ap should be taken daily when used together?
 
matthew76 said:
I'm sure USP will jump in soon - they're good about answering these type questions...

How do you like that STACK?
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looks good on paper!

I would like to see how it ranks with my no2, 6 oxo, ecedy, methoxy, krealkalyn stack that I always use to gain about 5lbs of lbm and droppin about 2% bf over a 2 month period.( I would say 2.5 lbs is from nitrogen retention from the test increase plus ecedy's nitrogen retention properties)

I have not used supps for over a yr, so I can give this a good honest evaluation!

If I find the usp labs stack to give good results(as good or better then my other stack)I will add activate and 94% ecedy either the 2nd month or the 3rd!

then if that all works out ,I will cough up some more dough if I can afford it and add 4 grams of 1:50 tongat ali from malaysia( I still have enuff to run 2 weeks as a trial from a old batch)


But I would really like to try the slin, ap, powerfull stack by itself since my body has been free of supps so long. this way I can really see its worth!

why look to this stack when the other one works? no2 gives me headaches and flush, 6 oxo has to be cycled and gives me sides,kre alkalyn, methoxy and ecedy I would still use after finding out the usplabs stack worth on its own!
 
I would dose AP twice a day, 20 minutes before breakfast and 20 minutes before last carb meal.

Dose the P-Slin 15 minutes pre-WO.

On the PFull issue, I'd need to see a dietary breakdown, because, as you said, it would depend on your carb intake.
 
Mulletsoldier said:
I would dose AP twice a day, 20 minutes before breakfast and 20 minutes before last carb meal.

Dose the P-Slin 15 minutes pre-WO.

On the PFull issue, I'd need to see a dietary breakdown, because, as you said, it would depend on your carb intake.
Click to expand...

heres my original plan

8am powerfull
9:45am p slin
10am breakfast pre workout meal 100 grams of oats/whole grain bread
noon powerfull
12:30 workout
1:30 carbs from fruit
2:15 anabolic pump
2:30 protien/complex carb meal
5:30 powerfull
6:30 protien/complex carb meal
8:00 some simple carb snack, "fruit"
8:45 anabolic pump
9:00 protien/ complex carb meal
11:00 protien meal( chicken or beef)
1 am powerfull

I dont consume any shakes do to be highly allergic to dairy, so all my protien comes from whole foods.

Can simple sugurs(honey,suger ect..) be used on the oats durring the pre workout meal?
 
ZIMM said:
heres my original plan

8am powerfull
9:45am p slin
10am breakfast pre workout meal 100 grams of oats/whole grain bread
noon powerfull
12:30 workout
1:30 carbs from fruit
2:15 anabolic pump
2:30 protien/complex carb meal
5:30 powerfull
6:30 protien/complex carb meal
8:00 some simple carb snack, "fruit"
8:45 anabolic pump
9:00 protien/ complex carb meal
11:00 protien meal( chicken or beef)
1 am powerfull

I dont consume any shakes do to be highly allergic to dairy, so all my protien comes from whole foods.

Can simple sugurs(honey,suger ect..) be used on the oats durring the pre workout meal?
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It looks alright, though before I give a detailed answer, is 12:30 the only time possible for you to workout? Ideally, I'd like you to be dosing AP/P-Slin 20 minutes before the pre-WO meal to really maximize nutrient partitioning before the workout.
 
I can really do my work out at anytime!
I can take the p slin 20 minutes prior to the pre workout meal.

OH I did not need that 5:30 powerfull in there since I have morning , pre workout and bedtime! this will allow me to move my meals up by 1 hr and my last carb meal will be at 8 pm.
 
Best utilization would be P-Slin before your workout (20 minutes) with PFull coming 10 minutes prior to that. Dose your PFull before your breakfast with AP. Then AP with last carb meal with PFull after that.
 
Mulletsoldier said:
Best utilization would be P-Slin before your workout (20 minutes) with PFull coming 10 minutes prior to that. Dose your PFull before your breakfast with AP. Then AP with last carb meal with PFull after that.
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Theres just a bit of conflicting information in this thread, or at least the way I have been reading it.
Is AP/P-Slin best 20 minutes before carb meals, or 15 like originally stated? I've been going with 15 lately.. is 20 mins a number that works better for people nowadays?
As a second question, how close to actually working out should the pre-workout meal come? Say 30 mins, 1 hour...

thanks
 
Highlanda01602 said:
Theres just a bit of conflicting information in this thread, or at least the way I have been reading it.
Is AP/P-Slin best 20 minutes before carb meals, or 15 like originally stated? I've been going with 15 lately.. is 20 mins a number that works better for people nowadays?
As a second question, how close to actually working out should the pre-workout meal come? Say 30 mins, 1 hour...

thanks
Click to expand...

Not conflicting, just 15-20 need not be utterly strict. It can be 15 or 20 minutes.

You do not need to do as such, but I personally like eating an hour pre-WO. Anything sooner than that won't serve your purpose.
 
Mulletsoldier said:
It looks alright, though before I give a detailed answer, is 12:30 the only time possible for you to workout? Ideally, I'd like you to be dosing AP/P-Slin 20 minutes before the pre-WO meal to really maximize nutrient partitioning before the workout.
Click to expand...


hey ms,
I can eat a preworkout meal 1 hr before my workout , I just put it at 1.5(2.5 in my chart accidently) hrs pre because I thought the powerfull needed at least that many hrs away from the carbs.

So would I still get the full effect of powerfull if I took
10 am pslin
10:20 preworkout meal
10:50 powerfull
11:20 workout
 
ZIMM said:
hey ms,
I can eat a preworkout meal 1 hr before my workout , I just put it at 1.5(2.5 in my chart accidently) hrs pre because I thought the powerfull needed at least that many hrs away from the carbs.

So would I still get the full effect of powerfull if I took
10 am pslin
10:20 preworkout meal
10:50 powerfull
11:20 workout
Click to expand...

That looks like a pretty decent protocol Zimm.
 
ZIMM said:
hey ms,
I can eat a preworkout meal 1 hr before my workout , I just put it at 1.5(2.5 in my chart accidently) hrs pre because I thought the powerfull needed at least that many hrs away from the carbs.

So would I still get the full effect of powerfull if I took
10 am pslin
10:20 preworkout meal
10:50 powerfull
11:20 workout
Click to expand...

Mullet was nursing some injures while the new PowerFULL protocol was developed. He is essentially correct on the answer, but I need to breif him again.

You Need to take PowerFULL 1 hour after a carb meal. best would be

9 am pslin
9:15 preworkout meal
10:15 powerfull
10:45-11 workout
 
USPLabs said:
Mullet was nursing some injures while the new PowerFULL protocol was developed. He is essentially correct on the answer, but I need to breif him again.

You Need to take PowerFULL 1 hour after a carb meal. best would be

9 am pslin
9:15 preworkout meal
10:15 powerfull
10:45-11 workout
Click to expand...

Ok perfect, Im glad that is all cleared up!
Would honey in the oatmeal be ok preworkout or would it interfere with the powerfull?
 
ZIMM said:
Ok perfect, Im glad that is all cleared up!
Would honey in the oatmeal be ok preworkout or would it interfere with the powerfull?
Click to expand...

the honey and the oatmeal would interfere. You should take PowerFULL 1 hour after eating carbohydrates.
 
would powerfull interfere with a ketogenic diet in anyway?

does powerfull raise insulin levels or glucose levels, wich would interfere with reaching ketosis?
 
USPLabs said:
In this case, you have to venture out and compare products. I encourage that approach.

When A company funds the study it immediately becomes flawed. As a consumer, I rather have 3rd party unaffliliated research on Human subjects which I presented.

Buy our Cissus and buy any other cissus product and compare the color, consitency, and texture. We proven that our extracts are different.
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Can you please explain me the diferences between the actual powerfull and the late version?
I ask this because with the late version (I think the second) I took 2 capsules and I sleept like a baby and with this new one nothing happens, I dont know if I`m the only one that have this problem but I` m sure something have changed.
 
nunes said:
Can you please explain me the diferences between the actual powerfull and the late version?
I ask this because with the late version (I think the second) I took 2 capsules and I sleept like a baby and with this new one nothing happens, I dont know if I`m the only one that have this problem but I` m sure something have changed.
Click to expand...

The formula is literally the exact same, the potency has merely been increased. Now, this increase in the potency might now be producing a stimulatory effect for you, as opposed to the opposite. Though your sleep should improve as a cumulative effect still.
 
Mulletsoldier said:
The formula is literally the exact same, the potency has merely been increased. Now, this increase in the potency might now be producing a stimulatory effect for you, as opposed to the opposite. Though your sleep should improve as a cumulative effect still.
Click to expand...

I will try with 1 pill only, lets see what happens...
 
djbombsquad said:
So would stacking with Trenadrol would be pointless? Increases gh levels than increase igf1 levels separately.
Click to expand...

No, it would help prevent the potential, progestin related, prolactin spikes from Trenadrol. Trenadrol's IGF-1 claims are a bit questionable IMO.
A Super Anabolic pro-testosterone formula-(17b methoxy-trienbolone)is 4x more powerful than popular steroid trenbolone and over 200 times moiré potent than methyl testosterone. Trenadrol was formulated to be anti-catabolic and double your igf-1 levels in your body for extreme muscle gains. Trenadrol is not your typical weak pro-hormone; it is the most powerful legal formula on the market today. Supplies are limited reserve your bottle of Trenadrol today!
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Trenadrol's claims are bull****, to put it nicely. All steroids raise IGF-1 levels to certain degrees, but, at least to me, it is doubtful Trenadrol raises it to that degree.
 
Well, you do not take Trenadrol, or any other steroid, for the IGF-1 increase. You take it for anabolism brah. So, if you are looking for a competent IGF source than Trenadrol isn't your bag.
 
I just don't want inject igf1. If any thing Id have to inject mgf and I don't want to do any IM injections currently. GHRP6 is more than enough for me with powerfull. I think the two are perfect.

Heck if powerfull increases igf1 high enough Id be happy.
 
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