Cordycepin, or 3'-deoxyadenosine is an ingredient which has the characteristics of being a pro-sexual, anti-inflammatory, anti-oxidant, anti-aging, anti-tumor, anti-leukemic, anti-proliferative, anti-metastatic, immunomodulatory, anti-microbial, anti-bacterial, anti-viral, anti-fungal, larvicidal, anti-fibrotic, steroidogenic, anti-diabetic, anti-HIV, anti-malarial, anti-fatigue, neuroprotective, liver-protective, reno-protective as well as being a pneumo-protective ingredient.
The recommended dosage is 100mg/serving. We're going to be including this high grade extract in our natural testosterone booster which will be launching late fall / mid winter.
As a testosterone booster:
Researchers investigated the in vivo and in vitro effects of Cordycepin in primary mouse Leydig cell steroidogenesis. [1] The results indicated that Cordycepin significantly increased the plasma Testosterone concentration. Cordycepin also stimulated in vitro mouse Leydig cell Testosterone production in dose- and time-dependent manners.
Cordycepin resembles adenosine in chemical structure, so the metabolic pathways of Cordycepin inside body should closely mimic those of adenosine. Researchers in the study proved this hypothesis. It has been confirmed that mouse testis contain several adenosine receptors, and Cordycepin activates the cAMP-PKA signal transduction pathway to induce StAR protein expression, and then enhances Testosterone production, possibly by
exerting its effect through adenosine subtype receptors A1, A2a, and A3.
According to the Testosterone elevation report, another research found long-term administration of Cordycepin could reverse the decline of testicular function induced with age. [2] In this piece of research, scientists divided the rats into a young group, a middle-aged group and treated the middle-aged group with Cordycepin. The middle-aged group exhibited epididymal weight loss, decreased sperm motility, and reduced spermatogenesis compared to the young control group. Interestingly enough, the epididymal weights of middle-aged rats were dose-dependently increased by long-term treatment with Cordycepin. Cordycepin also
improved calcium levels and decreased urea and nitrogen, uric acid, and creatinine in the blood of middle-aged rats. In addition, Cordycepin significantly increased sperm motility and the progressiveness of sperm movement. All Cordycepin-treated groups showed well-arranged spermatogonia, densely packed cellular material, and increased numbers of mature spermatozoa in the seminiferous lumen compared to the middle-aged control group.
References:
1. Sew-Fen LEU, Song Ling Poon, et al. The in vivo and in vitro stimulatory effects of Cordycepin on mouse Leydig cell steroidogenesis. Biosci. Biotechnol. Biochem., 75(4), 723-731, 2011.
2. Sang-Hyun Sohn, Su-Chan Lee, et al. Effect of Long-term Administration of Cordycepin from Cordyceps militaris on Testicular Function in Middle-aged Rats. Planta Med 2012; 78: 1620–1625.
. As you can see with the two new releases we are planning to reveal soon we are putting a lot of effort and much thought to make formidable 'mainstream' products as well. These 2 products will not disappoint and are extremely synergistic to one another.
