Oleylethanolamide (OEA)

[MultiVitamin]

Oleoylethanolamide (OEA) is synthesized in the intestines. Its synthesis is increased with food intake and decreased with fasting. OEA has been shown to have anorexic properties, meaning it decreases food intake.

A study done on rats showed that OEA's ability to decrease appetite did not change plasma levels of various intestinal hormones involved in satiety, such as ghrelin and CCK, showing OEA works independently of these hormones.

OEA is also an activator of the Peroxisome Proliferator-Activator Receptor Alpha (PPARalpha)

Activation of PPARalpha by OEA will cause an increase in fat oxidation along with a decrease in fat storage, creating an ideal environment for fat loss.

If all that weren't enough, OEA can also lower lower blood cholesterol and triglyceride levels.

Studies:
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More info:
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Any thoughts on this?

 

[mr.cooper69]

OEA has pretty good data, but it was used in several fat burners years ago and was eventually phased out because no one noticed anything from it.

 

[3clipseGT]

OEA has pretty good data, but it was used in several fat burners years ago and was eventually phased out because no one noticed anything from it.

Wasnt its absorbtion an issue? Kind of like Ursolic Acid?

 

[MultiVitamin]

Wasnt its absorbtion an issue? Kind of like Ursolic Acid?

That's what I figured looking back at past supplements that contained OEA. You think perhaps a better possibility?