New GDA? Arabidopsis thaliana extract (Mr coop pls)

[Auslifter]

found new gda inb4 in the new pes gda lol (idk)http://www.copharm.uobaghdad.edu.iq/uploads/activities 2014/jorunls/115-119.pdf

"The plant extract studied could be an answer to the people seeking for therapeutic agents from natural sources which is believed to be more efficient with a little or no side effects when compared to the synthetic chemotherapeutic agents."

"The hypoglycemic activity shown in this study may be related to the presence of flavonoids compounds which had very pronounces effect in the seed extract of this plant. Flavonoids may preserve β-cell function by reducing oxidative stress-induced tissue damage and therefore protect against the progression of insulin resistance to type 2 diabetes."

Results of this study are in harmony with the results demonstrated by Sheng et al. who found a hypoglycemic activity in Momordica charantia and Canavalia ensiflormis seed extracts.

 

[mr.cooper69]

I'll look into it. I wonder why it took so long for this to surface. In genetics, arabidopsis thaliana is the most well-studied plant in the world

 

[mr.cooper69]

Alright just read the whole thing. First, this is a REALLY low quality study on multiple levels. I don't know if it's the language gap or what, but the discussion section is an incoherent rambling of thought, and they essentially concluded it either reduces oxidative stress (worthless to healthy people) or carries insulin (but only in the genetically recombinant species, which probably aren't dshea-compliant)

 

[kbayne]

Interesting

 

[Auslifter]

Alright just read the whole thing. First, this is a REALLY low quality study on multiple levels. I don't know if it's the language gap or what, but the discussion section is an incoherent rambling of thought, and they essentially concluded it either reduces oxidative stress (worthless to healthy people) or carries insulin (but only in the genetically recombinant species, which probably aren't dshea-compliant)

huh iv been bored reading about strange herbs/plants lol. heres some more i found interesting to.

Sclerocarya birrea extract http://www.ncbi.nlm.nih.gov/pubmed/17141993http://www.ncbi.nlm.nih.gov/pubmed/15476310Sclerocarya birrea (Anacardiaceae) stem-bark ex... [J Endocrinol. 2010] - PubMed - NCBI http://www.ncbi.nlm.nih.gov/pubmed/17141993http://www.ncbi.nlm.nih.gov/pubmed/14692729

Phaleria macrocarpa http://www.ncbi.nlm.nih.gov/pubmed/23425283http://www.ncbi.nlm.nih.gov/pubmed/22547320"Moreover, it lowered blood glucose in diabetic rats by 66.67% (p < 0.05), similar to metformin (51.11%), glibenclamide (66.67%) and insulin (71.43%) after a 12-day treatment"Phaleria macrocarpa (PM)

Cajanus cajan root (MCC) Tamarindus indica seeds (MTI)http://www.ncbi.nlm.nih.gov/pubmed/24761124Cecropia pachystachya Hypoglycemic effects of Cecropia pachystach... [J Ethnopharmacol. 2010] - PubMed - NCBI

 

[booneman77]

In for info and speculation. Prime the rumor mill

 

[mr.cooper69]

Yeah I mean these rat anti-diabetic studies are everywhere, literally hundreds, maybe thousands of them. When the PES GDA comes into being, it will either have rodent data with "knock-your-socks-off" results that we just couldn't pass up, or it will have human data (likely both)

 

[booneman77]

Yeah I mean these rat anti-diabetic studies are everywhere, literally hundreds, maybe thousands of them. When the PES GDA comes into being, it will either have rodent data with "knock-your-socks-off" results that we just couldn't pass up, or it will have human data (likely both)

And there it is... the confirmation that a PES GDA is on the horizon. :boobies:

 

[mr.cooper69]

And there it is... the confirmation that a PES GDA is on the horizon. :boobies:

Well I mean everything is on the horizon. It just depends how far down

 

[Auslifter]

Yeah I mean these rat anti-diabetic studies are everywhere, literally hundreds, maybe thousands of them. When the PES GDA comes into being, it will either have rodent data with "knock-your-socks-off" results that we just couldn't pass up, or it will have human data (likely both)

haha im glad, or you could just gather a bunch that seem good and roll the dice ones like this sound legit since used by like tribes for cures ect,

In vitro antioxidant, antidiabetic and antilipidemic activities of Symplocos cochinchinensis (Lour.) S. Moore bark

Symplocos cochinchinensis (Lour.) S. Moore. is used in Indian system of traditional medicine to treat diabetes mellitus. The present study aims to investigate the antidiabetic efficacy of the hexane extract of Symplocos cochinchinensis leaves in high fat diet–low streptozotocin (STZ) induced type 2 diabetic rats.

in streptozotocin induced diabetic rat model. The experimental groups consist of normal control (NC), diabetic control (DC), DC+metformin 100mgkg(-1)bwd, DC+SCE 250 and DC+SCE 500. SCEs and metformin were administered daily for 21 days and sacrificed on day 22. Oral glucose tolerance test, plasma insulin, % HbA1c, urea, creatinine, aspartate aminotransferase, alanine aminotransferase, albumin, total protein etc. were analysed. Aldose reductase (AR) activity in the eye lens was also checked. On day 21, DC rats showed significantly abnormal glucose response, HOMA-IR, % HbA1c, decreased activity of antioxidant enzymes and GSH, elevated AR activity, hepatic and renal oxidative stress markers like malondialdehyde, protein carbonyls compared to NC. DC rats also exhibited increased level of plasma urea and creatinine. Treatment with SCE protected from the deleterious alterations of biochemical parameters in a dose dependent manner including histopathological alterations in pancreas. SCE 500 exhibited 46.28% of glucose lowering effect and decreased HOMA-IR (2.47), % HbA1c (6.61), lens AR activity (15.99%), and hepatic, renal oxidative stress and function markers compared to DC group. Considerable amount of liver and muscle glycogen was replenished by SCE treatment in diabetic animals. Although metformin showed better effect, the activity of SCE was very much comparable with this drug.

http://linkinghub.elsevier.com/retrieve/pii/S0378874110008949http://www.sciencedirect.com/science/article/pii/S0278691512000567http://en.wikipedia.org/wiki/Symplocos_stawelliihttp://www.ncbi.nlm.nih.gov/pubmed/21182925http://www.ncbi.nlm.nih.gov/pubmed/21681640http://scholarsresearchlibrary.com/ABR-vol1-iss2/ABR-2010-1-2-196-203.pdf


http://linkinghub.elsevier.com/retrieve/pii/S0378874110008949

http://www.sciencedirect.com/science/article/pii/S0278691512000567

http://en.wikipedia.org/wiki/Symplocos_stawellii

http://www.ncbi.nlm.nih.gov/pubmed/21182925

http://www.ncbi.nlm.nih.gov/pubmed/21681640

http://scholarsresearchlibrary.com/ABR-vol1-iss2/ABR-2010-1-2-196-203.pdf

 

[nattydisaster]

We do have a GDA in the making...not including this though

 

[Driven2lift]

We do have a GDA in the making...not including this though

Consider me first in line

 

[cbsharpe]

2nd in line :wink1:

 

[booneman77]

Cutting in line.

 

[Auslifter]

We do have a GDA in the making...not including this though

ill help make it LOL brb digging up research for pes so they make more supplements hnnnnnnnnnnnnng

 

[xhrr]

PES needs to come out with a joint/tendon supplement before this.

 

[jwsnowman]

First Techno and now a GDA being all but confirmed? I already have too many PES/Analyzed supps sitting on my shelf!