Natural AIs

Delita420

Active member
I've been doing some reading on herbal AIs, including damiana and chrysin. Can anyone report any experiences with these herbs? Does anyone know about other herbal AIs?
 
Zinc is a natural AI. You just have to be careful and not overdo it, since the margin between deficiency and toxicity is slim.
 
White mushrooms have been shown to be a natural aromatase inhibitors, with the stuffing variety (Agaricus bisporus) exhibiting the most potent aromatase inhibition (Baiba et al. 2001).

However it wasn't established from this study what component of the mushroom extract provided the aromatase inhibition and what form it should be eaten in to provide the greatest benefit.

A later study by Chen et al. (2006) has shown that the aromatase inhibition is likely to be rooted in the high concentrations of essential fatty acids, linoleic acid and conjugated linoleic acid (CLA), providing a transient anti-inflammatory effect and reducing aromatase activity. These anti-aromatase effects of CLA have been confirmed previously (Chen et al. 2004) as well as modulation of oestrogen receptor function (Durgam et al. 1997) and even suppression of aromatase mRNA expression (Chen et al. 2006).

So...while the humble mushroom isn't as potent as pharmaceutical compounds like exemestane, aromasin or letrozole at regulating the aromatase enzyme, it could be a nice, easy addition one's diet to help keep oestrogen at bay :)

Still wondering...the dosage of common CLA needed to elicit significant inhibition of aromatase enzyme, and whether the naturally-occurring CLA in the mushroom extract works synergistically with other compounds present to make the effect stronger?
 
7,8 benzoflavone...look into it. ;). Its used in Primoridal Performance's Sustain alpha. If 7,8 Benzoflavone and Trans-Resveratrol are applied topically they are much more effective. However, it does depend upon the quality of the TD carrier.

Cheers!:cheers:
 
White mushrooms have been shown to be a natural aromatase inhibitors, with the stuffing variety (Agaricus bisporus) exhibiting the most potent aromatase inhibition (Baiba et al. 2001).

However it wasn't established from this study what component of the mushroom extract provided the aromatase inhibition and what form it should be eaten in to provide the greatest benefit.

A later study by Chen et al. (2006) has shown that the aromatase inhibition is likely to be rooted in the high concentrations of essential fatty acids, linoleic acid and conjugated linoleic acid (CLA), providing a transient anti-inflammatory effect and reducing aromatase activity. These anti-aromatase effects of CLA have been confirmed previously (Chen et al. 2004) as well as modulation of oestrogen receptor function (Durgam et al. 1997) and even suppression of aromatase mRNA expression (Chen et al. 2006).

So...while the humble mushroom isn't as potent as pharmaceutical compounds like exemestane, aromasin or letrozole at regulating the aromatase enzyme, it could be a nice, easy addition one's diet to help keep oestrogen at bay :)

Still wondering...the dosage of common CLA needed to elicit significant inhibition of aromatase enzyme, and whether the naturally-occurring CLA in the mushroom extract works synergistically with other compounds present to make the effect stronger?

Interesting question(s).
 
apparently either green or black tea polyphenols, (or both?) not too sure i just saw this mentioned somewhere.
 
I noticed that a lot of the herbs used as AIs are rich in antioxidants... Could free radicals influence the aromatase enzyme?
 
Back
Top