MK-677

Mike Arnold

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I've noticed massive changes
But this protocol only elevates igf?

No. It elevates GH levels too. Increases in IGF-1 levels are the direct result of GH converting to IGF-1 in the liver. You must have missed it, but I in the prior post I said "That is exactly exactly what I would have recommended for MAXIMUM GH and IGF-1 levels."

It dosnt effect serum gh?
I ask because I'm getting to run some HGH for free
Just need to get bloods.
Source want me to shoot 10iu in felt and give blood 3.5 hours later
He said he's not concerned about the DAC just mk677
The DAC will have a large impact on your GH levels at 10 mg/week, so you absolutely should NOT get blood work with any sponsor's GH until you have been off DAC for an entire week. Getting bloodwork with DAC in your system will give a false reading by making the GH product look better than it actually is. Getting labs done under those conditions is completely worthless and will have no credibility.
Asked me to cut mk 2 days before test
That's fine.
....
 
Cgkone

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One study showed elevated levels from DAC 28 days later even. Maybe wait even longer
Yeah I'm going to go over it again with him
No way to get a hold of him for a week.

Sucks because I'm itching to start
But i need to make sure I got the plan right.
 
djbombsquad

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So I’m over 2 weeks now and i don’t know much of a difference between the cap and the power patch
 
djbombsquad

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Still can’t tell if it’s working . Second bottle
 
Rocket3015

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I always hate when this happens, you just aren't sure ???
 
djbombsquad

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I always hate when this happens, you just aren't sure ???
Yeah. I’m on my second bottle and I’m not any more hungry in fact when I eat more I just end up pooping it out lol . I will use it tor another 2 more bottles to give it s fair shot.
 

mjsmech

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Found an AMERICAN sourced supplier for my RESEARCH on MK677. and couldn't be happier. Been using them for the past 9 months. Started off with 25 mg ( 1 ml ) split dose ED but three months ago switched to once before bed. Usual negative sides subsided after first three bottles but sleep, recovery, workouts, and just everyday aches and pains ( 61 yrs old ) still great. Plan on running for a full year then getting some labs done. Also tried some of their liquid tadalafil. Great pumps on 6 drops sublingual. Very pleased with those results also, but not as pleased as my wife!
 

AntSoldier

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Sorry to hi-jack this thread but can anyone point me in the direction of a reputable UK retailer for MK677 or is there any I should avoid?
 
Febus

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Began taking MK about 2 weeks ago. So far hunger has increased, skin is healing up nicely and clearing up. Joints have been popping a lot which to me is a great thing, no sides yet.
I rarely sleep but when I do the sleep is incredibly refreshing.
 

franks009

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Can someone pm me on a source please. The RC board sponser is always sold out
 
Ricky10

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Can someone pm me on a source please. The RC board sponser is always sold out
PRE (Premier Research Essentials), another board sponsor always seems to have it on hand. I bought my last 4 bottles or so from them. I have not been able to try Ma Research MK-677 yet because of OOS issues.
 

franks009

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PRE (Premier Research Essentials), another board sponsor always seems to have it on hand. I bought my last 4 bottles or so from them. I have not been able to try Ma Research MK-677 yet because of OOS issues.
Thanks. Yea i just grabbed some from them. Even tho it was like 50% more than what MA advertises.
 
Ricky10

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I guess they know its in high demand so why not right lol
Yeah...well fortunately I am currently on a break from MK-677 altogether....so that is one expense I am not dealing with right now.
My prohormone cycle has cost me more than enough...
 

Stubsy

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I ran mk677 for 6 weeks and felt slight tingles in my right nipple. Im gonna run more but just wondering if anyone knows something i can take at the same time for my next run. Im in australia so not sure where i can get something. Any help would be appreciated
 
Ricky10

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I ran mk677 for 6 weeks and felt slight tingles in my right nipple. Im gonna run more but just wondering if anyone knows something i can take at the same time for my next run. Im in australia so not sure where i can get something. Any help would be appreciated
I usually seek out supplements that make my nipples tingle. MK-677 was not one of them for me...

It has been argued that MK-677 can temporary raise prolactin levels...but that is a debate in itself. Possibly your source has a little something special in it.

Bottom line, change sources, and/or try working in something simple like SNS Inhibit-P.
 
justhere4comm

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I ran mk677 for 6 weeks and felt slight tingles in my right nipple. Im gonna run more but just wondering if anyone knows something i can take at the same time for my next run. Im in australia so not sure where i can get something. Any help would be appreciated
Take for what? Some itching in your nipple? That could mean anything.
The first thing you need to do is get bloodwork, and test your prolactin levels along with the rest.

Pre and Post cycle bloods. Making assumptions could simply cause you to become the three letter precursor letters to the word umtions.
 

mjsmech

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American Research Labs. Been using for almost a year now. Great products, good prices, great customer service
 
tregar

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Febus said:
Began taking MK about 2 weeks ago. So far hunger has increased, skin is healing up nicely and clearing up. Joints have been popping a lot which to me is a great thing, no sides yet. I rarely sleep but when I do the sleep is incredibly refreshing.
Good to know.
 

Ripple2352

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I had a random question here that I didnt see asked, or talked about, in any other MK thread I've read. It's possible I missed a lot lol, so apologies if this is something that's been discussed as nauseam.

Common side effects of GH are a slight rise in fasting blood sugar levels, and a decrease to insulin sensitivity over time. I'm looking at taking MK for a minimum of 6 months, but at the 12.5mg per day dosage. I already use GDAs, but I'm wondering if the use of GDAs will help to mitigate some of the effects on insulin and blood sugar that MK/GH may have? Anyone any experience? I know to expect an increase in appetite, and I'll have to see how that goes, but I'm not planning on increasing carb intake while on MK, and will be (trying my damndest at least) to do a 18-24hr fast one a week. Thoughts?
 

Ripple2352

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I had a random question here that I didnt see asked, or talked about, in any other MK thread I've read. It's possible I missed a lot lol, so apologies if this is something that's been discussed as nauseam.

Common side effects of GH are a slight rise in fasting blood sugar levels, and a decrease to insulin sensitivity over time. I'm looking at taking MK for a minimum of 6 months, but at the 12.5mg per day dosage. I already use GDAs, but I'm wondering if the use of GDAs will help to mitigate some of the effects on insulin and blood sugar that MK/GH may have? Anyone any experience? I know to expect an increase in appetite, and I'll have to see how that goes, but I'm not planning on increasing carb intake while on MK, and will be (trying my damndest at least) to do a 18-24hr fast one a week. Thoughts?
Bump for anyone :)
 

Ripple2352

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I had a random question here that I didnt see asked, or talked about, in any other MK thread I've read. It's possible I missed a lot lol, so apologies if this is something that's been discussed as nauseam.

Common side effects of GH are a slight rise in fasting blood sugar levels, and a decrease to insulin sensitivity over time. I'm looking at taking MK for a minimum of 6 months, but at the 12.5mg per day dosage. I already use GDAs, but I'm wondering if the use of GDAs will help to mitigate some of the effects on insulin and blood sugar that MK/GH may have? Anyone any experience? I know to expect an increase in appetite, and I'll have to see how that goes, but I'm not planning on increasing carb intake while on MK, and will be (trying my damndest at least) to do a 18-24hr fast one a week. Thoughts?
Thoughts, or a friendly push towards some relevant information about this issue from anyone?
 
Rocket3015

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Thoughts, or a friendly push towards some relevant information about this issue from anyone?
Just start at page one in this thread, a ton of info here!
 

Ripple2352

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Well, yes, GDAs lower blood sugar.
I just want really sure if it was something significant that people were seeing and even GDAs wouldnt really help with much, or if it was something that could be easily mitigated with IF and/or GDA use while on.
 
Old Witch

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I just want really sure if it was something significant that people were seeing and even GDAs wouldnt really help with much, or if it was something that could be easily mitigated with IF and/or GDA use while on.
That’s going to depend entirely on whether you respond well to things like berberine in the first place. No doubt though when your fasting blood sugar is up at 150 or something, that’s not good. You’ll need to do SOMETHING for that. I’ve always said anytime you’re taking GH you should use either a long acting insulin or even IGF1-LR3 which is going to be the two most anabolic options. Berberine is more effective than metformin as far as GDAs go.

Your blood sugar should cruise around 90 when fasted.
 

Ripple2352

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That’s going to depend entirely on whether you respond well to things like berberine in the first place. No doubt though when your fasting blood sugar is up at 150 or something, that’s not good. You’ll need to do SOMETHING for that. I’ve always said anytime you’re taking GH you should use either a long acting insulin or even IGF1-LR3 which is going to be the two most anabolic options. Berberine is more effective than metformin as far as GDAs go.

Your blood sugar should cruise around 90 when fasted.
Woooooh I didnt know fasting blood sugar would hover around 150 or so. Yikes! Thanks for that! Something like that was EXACTLY what I was looking for! Allows me to make a more informed decision! My current fasting blood sugar is fine, luckily. I mainly wanted to use it for its sleep and recovery benefits, and I have some Achilles tendonitis that I'm having a hard time getting over. I was hoping that would help. My whole thing was that even though neither of my parents are diabetic, my grandmother on my mother's side was and that's what eventually took her. So that was a very big concern of mine for obvious reasons.
 

Toff

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MK677 - two years on from when it hit the market are we any closer to a) certification for human use b) anyone died of supersized organs or other affects?
 
Rocket3015

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MK677 - two years on from when it hit the market are we any closer to a) certification for human use b) anyone died of supersized organs or other affects?
I have not heard of a single permanent negative side effect
 
justhere4comm

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It would appear that Keto + MK 677 would introduce the best possible environment to reduce sides.
Insulin Resistence issues and potential bloat. As an old guy looking for the micro-fountain of youth...
 
Godstrength

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MK677 - two years on from when it hit the market are we any closer to a) certification for human use b) anyone died of supersized organs or other affects?
Its already available as a prescription medication as ibutamoren in the US.
 

jtbull

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Only thing i worry about from it is becoming diabetic and i hear that if anything problems can be adjusted with some type of supplement or just taking sugar. If i dont go mk i also thought about peptides probably semorlin and ipermaorion? or something like that they are called. Whichever has the lower sides. I have also seen some talk of injectable l arganine helping if done at night
 

muchstronger2

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Looks like a lab is making a pharmaceutical-quality MK-677:
www.schlobesser-pharma.com

Anyone tried? Legit?

Also heard that it's starting to become available under prescription at anti-aging clinics. Has it become legal?
 

Mr Giggles

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Does MK-677 cause any shutdown/suppression? I guess not, right?
 
Rocket3015

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jtbull

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I really want to try it, but more and more i hear about water retention. I am debating about a peptide, but i need to find one that only has to be injected once per day and HGH is a bit too expensive. I hear mk677 is really good but the consensus is you need to be on it at least 6 months. Seems i can get a good bit of gear for that price.
 

Cycloman

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MK 677 does not cause any shut down at all- rather the opposite – it stimulates your own production similar to how Clomid stimulates your testes to produce testosterone. As for water retention – I’ve dosed at 12.5 mg per day and had minimal bloating – and also switch to that dose every other day and still retained some of the healing and sleep benefits with zero bloat. If you’re looking for an alternative, try Ipamorelin – I’ve been reading a lot about and intend to try a cycle. One injection per day and has more fat burning qualities than MK and will also not shut you down.
 
THOR 70

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MK expanded my guts. Either by my fat ass eating a ton of carbs, or by its own mechanism. If my goal was to get to 350lbs and huge, this would be my drug of choice. Cool drug but not benign
 

Ripple2352

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MK expanded my guts. Either by my fat ass eating a ton of carbs, or by its own mechanism. If my goal was to get to 350lbs and huge, this would be my drug of choice. Cool drug but not benign
Expanded your guts? Lol nah...it doesnt raise GH anywhere near the levels needed to actually do any of that. It was most definitely bloat/carbs/appetite. Whether or not one considers it "benign" is completely subjective, but when looking at MK next to darn near any other "drug"/PH/Sarm, then yes, comparatively, it is benign when researched and used properly.
 

jtbull

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Actual GH therapy needs to be pulsed in a low dose about 1IU every 3-4 hours.

MK677 only proves that if you dose a GHRP high enough it will be effecitve orally.

You could just do 100mcg of GHRP-2 with 100mcg of Mod GRF (1-29) and save yourself the hassle.
How often do you have to inject these? I know there are some that seem to be done multiple times per day. I am looking for peptides that are once a day.

I have thought of mk677 myself, but seems more and more i read about it people are talking about being hungry as hell and water pickup. Plus with the price of one month of mk677 is almost the same as 10 weeks of a 200mg test. I could be missing out though so i am regularly checking on the thoughts on these.
 

jim2509

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Woooooh I didnt know fasting blood sugar would hover around 150 or so. Yikes! Thanks for that! Something like that was EXACTLY what I was looking for! Allows me to make a more informed decision! My current fasting blood sugar is fine, luckily. I mainly wanted to use it for its sleep and recovery benefits, and I have some Achilles tendonitis that I'm having a hard time getting over. I was hoping that would help. My whole thing was that even though neither of my parents are diabetic, my grandmother on my mother's side was and that's what eventually took her. So that was a very big concern of mine for obvious reasons.
This is the issue i 'keep' coming back to when i consider running Lgd/Rad 140/Mk677 stack. The concern over elevated Blood Sugar with MK677 that ok may subside once usage ceases..BUT longterm may cause issues down the line. Probably going to have to just run Lgd/Rad 140 stack with 'test base' of dermacrine or 4-AD. Really wanted to give Mk677 a whirl but the theres a pretty much ?? over the Blood Glucose issue.
 
tregar

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Let me clear up a couple of the thoughts above,

In 2018, I took 25mg in the morning from March till November (8 months), though now I only take it 7 months straight, then take a 5 month break off.

My levels after 4 weeks on it measure 327 igf-1 ng/ml, up from my baseline of 227, so a 100 point increase, I read at the high end for an 18 year old on my GH and igf-1 levels while on it, and I am age 49 bodybuilder, so more than happy. 30% greater strength gains over time, good nootropic energy during day, sleep great at night, keeps joins lubricated, and enhanced exercise tolerance in the gym and on treadmill. No lethargy at all here during the day, unlike many I have read about. A few pages about the mk677 in the book "grow young with hgh" by Klatz too.

7 months in while taking it, I had labs done, mk677 had no detrimental effects on my insulin, glucose, A1c, etc.

Labs from Sept 26, 2018:

Insulin 8.2 uU/ml , normal, low =2.6, high = 24.9
Glucose: 89.0 mg/dl, normal, low = 70, high = 99
HbA1c: 5.1%, normal, low = 4.0, high = 5.6

I recommend you take 300mg of +R-ALA (Dr. Danielle Alpha Lipoic Acid, RALA, Extremely High Quality Alpha R Lipoic Acid (R-ALA)R- ALA 120 Capsules) before every meal x 3 times a day to help counteract and even improve insulin sensitivity while on either HGH or mk677, as yes, both will lower insulin sensitivity a bit, but this can be improved considerably with +R alpha lipoic acid, p.s. I get no hearburn from the above formula, best I have tried, and I have tried 3 different brands. I was not taking +R-ALA during the months the lab was taken above, but have since added it this year during my 7 month of the year mk677 25mg a day cycle.

Liver values also normal after 7 months of use:

ALT 26.0 u/L, normal, low =7, high =56.0
AST 21.0 u/L normal, low = 5, high = 35

MK677 is also not expensive, try xian Lyphar biotech in China, around twenty bucks a gram, don't pay the ridiculous prices charged for it here in the USA, as they are but the middleman who get it from China anyways.
 
Last edited:

jim2509

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Let me clear up a couple of the thoughts above,

In 2018, I took 25mg in the morning from March till November (8 months), though now I only take it 7 months straight, then take a 5 month break off.

My levels after 4 months on it measure 327 ng/ml, up from my baseline of 227, so a 100 point increase, I read at the high end for an 18 year old on my GH and igf-1 levels while on it, and I am age 49 bodybuilder, so more than happy.
30% greater strength gains over time, good nootropic energy during day, sleep great at night, keeps joins lubricated, and enhanced exercise tolerance in the gym and on treadmill. No lethargy at all here during the day, unlike many I have read about. A few pages about the mk677 in the book "grow young with hgh" by Klatz too.

7 months in while taking it, I had labs done, mk677 had not detrimental effects on my insulin, glucose, A1c, etc.

Labs from Sept 26, 2018:

Insulin 8.2 uU/ml , normal, low =2.6, high = 24.9
Glucose: 89.0 mg/dl, normal, low = 70, high = 99
HbA1c: 5.1%, normal, low = 4.0, high = 5.6

I recommend you take 300mg of +R-ALA (Dr. Danielle Alpha Lipoic Acid, RALA, Extremely High Quality Alpha R Lipoic Acid (R-ALA)R- ALA 120 Capsules) before every meal x 3 times a day to help counteract and even improve insulin sensitivity while on either HGH or mk677, as yes, both will lower insulin sensitivity a bit, but this can be improved considerably with +R alpha lipoic acid, p.s. I get no hearburn from the above formula, best I have tried, and I have tried 3 different brands. I was not taking +R-ALA during the months the lab was taken above, but have since added it this year during my 7 month of the year mk677 25mg a day cycle.

Liver values also normal after 7 months of use:

ALT 26.0 u/L, normal, low =7, high =56.0
AST 21.0 u/L normal, low = 5, high = 35

MK677 is also not expensive, try xian Lyphar biotech in China, around twenty bucks a gram, don't pay the ridiculous prices charged for it here in the USA, as they are but the middleman who get it from China anyways.












Dr. Danielle Alpha Lipoic Acid, RALA, Extremely High Quality Alpha R Lipoic Acid (R-ALA)R- ALA 120 Capsules
Hi mate, what BRILLIANT and informative read with information that am sure will be a benefit to many on here interested in MK677. Being 44 years old this has definately assisted me and i have been doing some further reading as well on Mk677....i think its definately a worthwhile supplement for me.

Regarding ALA supplementation, I have Berberine which i was going to take 3 x day with meals...you think ALA would be a better option?? Seems you've had good results with that keeping your blood sugars stable.
 
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