That pretty much says it all...I don't dispute that ppl feel better using glutamine, just realize what mechanisms are at play before you argue that it's a miracle supplement. IMO it may be possible that the ppl who see "results" from glutamine may have lower base levels of plasma glutamine, and supplementing with it raises them up to a healthy range...who knows? Regardless, most protein powders will supply you with plenty of glutamine. That being said, there is no harm in taking what you have already purchased.
Yes I definitely agree here. Some PPL like myself may not down enough protein shakes for full saturation of glutamine stores so supplemental glutamine seems helpful for recovery(right after WO).Other times of day less useful.
Heard L-Glutamine helpful for alcoholics also, decreasing cravings for alcohol ,ect.
Oral L-glutamine increases GABA levels in striatal tissue and extracellular fluid
Lei Wang, Timothy J. Maher, and Richard J. Wurtman
We explored the possibility that circulating glutamine affects -aminobutyric acid (GABA) levels in rat striatal tissue and GABA concentrations in striatal extracellular fluid (ECF). Striatal microdialysates, each collected over a 20 min interval, were obtained after no treatment, oral L-glutamine (0.5 g/kg), or glutamine followed by NMDA (administered via the microdialysis probe). GABA concentrations were measured by HPLC using a stable OPA/sulfite precolumn derivatization and an electrochemical detection method. L-Glutamine administration significantly increased ECF GABA concentrations by 30%, and enhanced the response evoked by NMDA alone (70%) to 120% over baseline (all P<0.05). Striatal GABA levels increased significantly 2.5 h after oral L-glutamine (e.g., from 1.76 ± 0.04 µmol/g in vehicle-treated rats to 2.00 ± 0.15 µmol/g in those receiving 2.0 g/kg of glutamine). Striatal glutamine levels also increased significantly, but not those of glutamate. These data suggest that GABA synthesis in, and release from, rat striatum may be regulated in part by circulating glutamine. Hence, glutamine administration may provide a useful adjunct for treating disorders (e.g., anxiety, seizures) when enhanced GABAergic transmission is desired. Moreover, the elevation in plasma and brain glutamine associated with hepatic failure may, by increasing brain GABA release, produce some of the manifestations of hepatic encephalopathy.--Wang, L., Maher, T. J., Wurtman, R. J. Oral L-glutamine increases GABA levels in striatal tissue and extracellular fluid.
another one:
REVERSAL OF ALCOHOL TOXICITY BY GLUTAMINE
Joanne M. Ravel, Barbara Felsing, Edwin M. Lansford, Jr., Robert H. Trubey, and William Shive
J. Biol. Chem., Jun 1955; 214: 497 - 501.