I'll add in that tianeptine sodium was hell for me. The first couple weeks were bliss, I was walking around on air thinking, how can this be so unknown yet legal? Took away all anxiety, stress, everything...that should have been a sign. Then after about 3-4 weeks my wife commented that I had been really edgy and almost robotic when arguing. I was shocked because I had no idea and even when she told me, I of course became defensive and started that circle again. It took one of my kids to make a comment about me being in a bad mood when I thought I was in a great mood. I knew at that point, it was the tianpetine that had to go. I was not taking a lot, so I decided to just stop.
The first day was hard because I missed the feel of not caring and I started to notice normal thoughts coming into my mind and unfortunately, the anxiety building was not allowing me to address it. Days 2-5 were the worst with full anxiety all day long and sadness (I won't call it depression). Everything made me sad. I tried to take some 5-htp thinking it was hitting my seratonin, but that didn't make a dent. Adding in 2 a day cardio to try and build up endorphins, but I had little energy. I was just down, down, down. After about 7-10 days I started to see some of the anxiety going away and sleeping better. All in all, it took me about 2 weeks to completely come back to normal- after only about 6 weeks on.
Now, keep in mind this was the sodium version which is what gives the nice "high". The sulfate has a much longer half life and anecdotal reports seem to read that people don't have the same difficulty, but also don't get the same effects.
Speaking of vicaine, I had it out with the owner of the company on a long thread and IM regarding adding in tianeptine sodium, and it went no where. But, people should be cautious of the ingredient.