P.G. 600 is a combination of serum gonadotropin (Pregnant Mare Serum Gonadotropin or PMSG) and chorionic gonadotropin (Human Chorionic Gonadotropin or HCG) for use in prepuberal gilts (gilts that have not yet exhibited their first estrus) and in sows at weaning. It is supplied in freeze-dried form with sterile diluent for reconstitution.
In gilts and sows, the action of serum gonadotropin is similar to the action of Follicle-Stimulating Hormone (FSH), which is produced by the animals’ anterior pituitary gland. It stimulates the follicles of the ovaries to produce mature ova (eggs), and it promotes the outward signs of estrus (heat).
The action of chorionic gonadotropin in gilts and sows is similar to the action of Luteinizing Hormone (LH), which is also produced by the animals’ anterior pituitary gland. It causes the release of mature ova from the follicles of the ovaries (ovulation), and it promotes the formation of corpora lutea, which are necessary for the maintenance of pregnancy once the gilt has become pregnant.
The combination of serum gonadotropin and chorionic gonadotropin in P.G. 600 induces fertile estrus in most prepuberal gilts and weaned sows three to seven days after administration (Schilling and Cerne, 1972; Britt et al., 1986; Bates et al., 1991). The animals may then be mated or, in the case of gilts, mating may be delayed until the second estrus after treatment.
NOTE: P.G. 600 IS INTENDED AS A MANAGEMENT TOOL TO IMPROVE REPRODUCTIVE EFFICIENCY IN SWINE PRODUCTION OPERATIONS. TO OBTAIN MAXIMUM BENEFIT FROM THIS PRODUCT, ESTRUS DETECTION AND OTHER ASPECTS OF REPRODUCTIVE MANAGEMENT MUST BE ADEQUATE. IF YOU ARE IN DOUBT ABOUT THE ADEQUACY OF YOUR BREEDING PROGRAM, CONSULT YOUR VETERINARIAN.
P.G. 600 is available in two package sizes:
SINGLE DOSE VIALS (order Code No. PG-720-1) - Five vials containing white freeze-dried powder, plus five vials containing sterile diluent. When reconstituted, each single dose vial (5 mL) of P.G. 600 contains:
[TD="colspan: 1, align: left"] SERUM GONADOTROPIN (PMSG)
[/TD]
[TD="colspan: 1, align: left"] 400 IU
[/TD]
[TD="colspan: 1, align: left"] CHORIONIC GONADOTROPIN (HCG)
[/TD]
[TD="colspan: 1, align: left"] 200 IU
[/TD]
(equivalent to 200 USP Units chorionic gonadotropin)
FIVE DOSE VIALS (order Code No. PG-720-5) - One vial containing white freeze-dried powder, and one vial containing sterile diluent. When reconstituted, the five dose vial (25 mL) of P.G. 600 contains:
[TD="colspan: 1, align: left"] SERUM GONADOTROPIN (PMSG)
[/TD]
[TD="colspan: 1, align: left"] 2000 IU
[/TD]
[TD="colspan: 1, align: left"] CHORIONIC GONADOTROPIN (HCG)
[/TD]
[TD="colspan: 1, align: left"] 1000 IU
[/TD]
(equivalent to 1,000 USP Units chorionic gonadotropin)
