GH kills fat cells?

judge-mental

Board Supporter
Check this out. I noticed on the label (on the internet ofcourse, I don't have GH in my disposal) that it shouldnt be injected into fatty areas so as to not causing lypoatrophy..
excuse me?
please do cause lypoatrophy...

hot damn?

anyone can verify this off hand before I dig in?
 
Fat cells respond to hGH by releasing some of their content in the bloodstream. Injecting sub-q will saturate the receptor of the fat cells in the surrounding area, causing them to release a good part of their content. This may cause a pockmarked injection area, i.e. a "hole" in the bodyfat at the injection point.

There are documented cases around on the boards. Don't know if they have pics though...

OTOH, pubmed says this :

Clin Endocrinol Metab. 1982 Nov;55(5):1003-6. Invalid Link Removed Links
A comparison of subcutaneous and intramuscular administration of human growth hormone in the therapy of growth hormone deficiency.

Invalid Link Removed, Invalid Link Removed.

The sc and im administration of human GH (hGH) was compared in the therapy of GH deficiency. The peak and integrated concentrations of hGH in the plasma of the patients were similar after sc and im injection of an initial dose (0.1 U/kg) of hGH. The peak hGH concentration occurred at 2 h in both groups. The posttreatment height velocity and the change in height velocity at 3-month intervals were also similar in the im and sc groups. The somatomedin generation test resulted in a higher mean peak of somatomedin C after sc injection; however, if the individual peaks of somatomedin C were averaged, there was no difference between sc and im injection. A cross-over at 9 months of therapy to determine patient acceptance of im vs. sc injections indicated overwhelming acceptance of the sc route. The antibody responses to hGH were similar in both groups. We conclude that sc injection of hGH is an effective and safe mode of therapy for GH deficiency. The lipoatrophy that occurred infrequently at the injection site can be eliminated by rotation of sites. Subcutaneous administration of hGH will be more acceptable by the patients with less pain and less noncompliance.

PMID: 6889608 [PubMed - indexed for MEDLINE]

Now, we must keep in mind that this is about GH therapy, where they try to make up for lack of endogenous GH with injections of physiological doses. A lot of people using hGH use supraphysiological doses, which makes these holes in the bodyfat a possibly more important factor.

And there's this too, I'm sure someone can get the full text and send it to you via email or even post it here, leave it here for a little bit then delete it, because, well you know... ;)

Lab Clin Med. 1971 Dec;78(6):1003-4. Invalid Link Removed Links
Elevated human growth hormone (HGH) levels in partial and total lipoatrophy.

Invalid Link Removed, Invalid Link Removed, Invalid Link Removed.

PMID: 5131829 [PubMed - indexed for MEDLINE]
 
what do you mean by pochmark?

and BTW you can get a little deeper than that. which receptor? HGH receptor agonizes HSL? promotes cytokine release?
 
A pockmark is akin to a dent. Just imagine what it would look like if you had all this fat around a random area without any.
 
well I could just hypotheticaly dent myself every day in a differebt place, not poch but dead fat cells...

Im interested to know how its actualy working
 
For about 60 days, I have been using jinos at 5iu per day, injected sub-q in my gut (all before bed as I am 40 and have little GH produced naturally anyway). I can tell you that I have had "honey handles" all my life until I started this ****. A couple of days, I did 10iu split morning and night, and I swear I almost looked svelte in the middle. Combined with a consistent ab workout program, I can say without hesitation that GH is an extraordinarily effective (albeit expensive) way to reduce stubborn fat deposits in the mid-section.
 
5IU per day? did you have any sides like joint pain or wider belly?
PS how mcuh do you weigh and what is your height?
 
judge-mental said:
5IU per day? did you have any sides like joint pain or wider belly?
PS how mcuh do you weigh and what is your height?
Click to expand...
No wider belly--exactly the opposite, but I have had swelling in the hands and some joint pain, but nothing like you get on a high dose of IGF. I'm 224lbs and 5'11'' and about 17% body fat.
 
I been using GH to cut for a while at only 1IU a day... with weeknds off.. and i am leaning out very nice. You do no need alot of GH to cut. GH to gain mass you need alot more.
 
IRONPOPE said:
I been using GH to cut for a while at only 1IU a day... with weeknds off.. and i am leaning out very nice. You do no need alot of GH to cut. GH to gain mass you need alot more.
Click to expand...

Holy hell only 1iu and you have noticed results?

You must have serostim or hyge or other top notch RX grade GH, because generics wont do that!

-Matt
 
i got top of the line GH..... wont mention who or what or how... but its primo. i will do a 2iu or 3iu shot mixed in here n there... but for the most part just constant 1iu .. gonna play with some peptides shortly
 
I have access to hygertropin I may get about 300iu and run at 3 iu a day with weekends off.... Hmmmm
 
IRONPOPE said:
I been using GH to cut for a while at only 1IU a day... with weeknds off.. and i am leaning out very nice. You do no need alot of GH to cut. GH to gain mass you need alot more.
Click to expand...

How old are you?

I "felt" better on 2iu's, recovery and sleep was so much better than usual, but didn't really "see", fatwise, difference until I did 3+...

I want your stuff!!!
 
Parteeman said:
For about 60 days, I have been using jinos at 5iu per day, injected sub-q in my gut (all before bed as I am 40 and have little GH produced naturally anyway). I can tell you that I have had "honey handles" all my life until I started this ****. A couple of days, I did 10iu split morning and night, and I swear I almost looked svelte in the middle. Combined with a consistent ab workout program, I can say without hesitation that GH is an extraordinarily effective (albeit expensive) way to reduce stubborn fat deposits in the mid-section.
Click to expand...

How do you make sure the whole thing is even and not get anywhere hollowed?
 
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