EvoMuse BMP Writeup (UPDATED)

Tank999 said:
Got 3 packets of bmp solid rock. Any ideas how to make them useable?
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They should break up pretty easy. Those ones that were done and shipped in the middle of Summer really hardened up quite a bit.

I asked for a vote for who wanted me to add something in there to keep it from going solid, but nobody seemed to want it. Is that still the case?
 
dsade said:
They should break up pretty easy. Those ones that were done and shipped in the middle of Summer really hardened up quite a bit.


I asked for a vote for who wanted me to add something in there to keep it from going solid, but nobody seemed to want it. Is that still the case?
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My vote is for additive for powder issue and obviously amount used so we know what adjusted serving size is. To help with rocked up bags, I literally used a butcher knife and cutting board.
 
I agree with the additive. I have six waiting for my next surplus, luckily only one had hardened during my shipping process.
 
Since I have to get the labels reprinted anyway (the bakuchiol didn't work out) I will go ahead and make the adustment. It doesn't take much really.
 
Reminder, BMP mixes and tastes great in green tea for anyone who's looking for an alternative way to take the powdered form
 
jathan_howe said:
Reminder, BMP mixes and tastes great in green tea for anyone who's looking for an alternative way to take the powdered form
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Does it affect coffee taste? Haven't used my powdered form yet.
 
shockrock3 said:
Wait is killing me...using 1 serving a day to conserve
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Had a little miscommunication with the new owner of the ingredient company. He didn't realize that what I sent was an actual purchase order.

We're still ironing out the new processes to keep things organized, but it shouldn't be long now.
 
dsade said:
Had a little miscommunication with the new owner of the ingredient company. He didn't realize that what I sent was an actual purchase order.

We're still ironing out the new processes to keep things organized, but it shouldn't be long now.
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Great, I have yet to try BMP and am looking forward to giving it a whirl.
 
dsade said:
Had a little miscommunication with the new owner of the ingredient company. He didn't realize that what I sent was an actual purchase order.

We're still ironing out the new processes to keep things organized, but it shouldn't be long now.
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Good to hear Matt, will be ordering a good amount for both myself and clients...
 
I should have an ETA this week.
 
It's on order still, but I don't have the tracking number yet. Hoping for more info by tomorrow (they are closed today.)
 
As posted in the Supernova thread. Not only do we get increased energy expenditure, crippling of fat storage enzymes, activation of brown fat, conversion of white cells to BRITE cells, but we have a potent activation of BMP7. Since the Bakuchiol didn't work out, and since I can get Rose Hips concentrated extract, I think I will go ahead and include the RHE in the next BMP powder that will be here in a few weeks.

Nutr Metab (Lond). 2016 Dec 6;13:91. eCollection 2016.
Rose hip supplementation increases energy expenditure and induces browning of white adipose tissue.
Cavalera M1, Axling U1, Berger K1, Holm C1.
Author information
Abstract
BACKGROUND:

Overweight and obesity are widespread chronic disorders defined as excessive fat accumulation, and are major risk factors for several chronic diseases including type 2 diabetes, coronary heart disease, high blood pressure and fatty liver. Changes in lifestyle such as increased physical activity and a healthy diet can be crucial tools for treating obesity. Intake of rose hip, the fruit of several plants belonging to the Rosaceae family, has been shown to reduce body fat mass and prevent body weight gain. Thus, the aim of the study was to elucidate potential mechanisms through which rose hip inhibit diet-induced obesity.
METHODS:

C57BL/6 J mice were fed a high fat diet with (RH) or without (CTR) rose hip supplementation for three months. In vivo indirect calorimetry was monitored, as well as gene expression and protein levels of different adipose depots.
RESULTS:

Although no differences in energy intake were found compared to the CTR group, RH prevented body weight gain and lowered blood glucose, insulin and cholesterol levels. Indirect calorimetry showed that RH-fed mice have significantly higher EE during the dark phase, despite comparable voluntary activity. Moreover, when challenged with treadmill running, RH-fed mice exhibited higher metabolic rate. Therefore, we hypothesized that RH could stimulate the brown adipose tissue (BAT) thermogenic capacity or may induce browning of the white adipose tissue (WAT). Compared to the CTR group, gene expression and protein levels of some brown and "brite" markers, together with genes able to promote brown adipocyte differentiation and thermogenesis (such as ucp1, tbx15, bmp7, and cidea), as well as phosphorylation of AMPK, was increased in WAT (but not in BAT) of RH-fed mice.
CONCLUSIONS:

Taken together these results indicate that dietary rose hip prevents body weight gain by increasing whole body EE and inducing browning of WAT. Thus, it has potential therapeutic implication for treatment of obesity and related metabolic disorders.
KEYWORDS:

Browning; Diet; Energy expenditure; Obesity; Rose hip

PMID:
27980600
PMCID:
PMC5139088
 
dsade said:
As posted in the Supernova thread. Not only do we get increased energy expenditure, crippling of fat storage enzymes, activation of brown fat, conversion of white cells to BRITE cells, but we have a potent activation of BMP7. Since the Bakuchiol didn't work out, and since I can get Rose Hips concentrated extract, I think I will go ahead and include the RHE in the next BMP powder that will be here in a few weeks.

Nutr Metab (Lond). 2016 Dec 6;13:91. eCollection 2016.
Rose hip supplementation increases energy expenditure and induces browning of white adipose tissue.
Cavalera M1, Axling U1, Berger K1, Holm C1.
Author information
Abstract
BACKGROUND:

Overweight and obesity are widespread chronic disorders defined as excessive fat accumulation, and are major risk factors for several chronic diseases including type 2 diabetes, coronary heart disease, high blood pressure and fatty liver. Changes in lifestyle such as increased physical activity and a healthy diet can be crucial tools for treating obesity. Intake of rose hip, the fruit of several plants belonging to the Rosaceae family, has been shown to reduce body fat mass and prevent body weight gain. Thus, the aim of the study was to elucidate potential mechanisms through which rose hip inhibit diet-induced obesity.
METHODS:

C57BL/6 J mice were fed a high fat diet with (RH) or without (CTR) rose hip supplementation for three months. In vivo indirect calorimetry was monitored, as well as gene expression and protein levels of different adipose depots.
RESULTS:

Although no differences in energy intake were found compared to the CTR group, RH prevented body weight gain and lowered blood glucose, insulin and cholesterol levels. Indirect calorimetry showed that RH-fed mice have significantly higher EE during the dark phase, despite comparable voluntary activity. Moreover, when challenged with treadmill running, RH-fed mice exhibited higher metabolic rate. Therefore, we hypothesized that RH could stimulate the brown adipose tissue (BAT) thermogenic capacity or may induce browning of the white adipose tissue (WAT). Compared to the CTR group, gene expression and protein levels of some brown and "brite" markers, together with genes able to promote brown adipocyte differentiation and thermogenesis (such as ucp1, tbx15, bmp7, and cidea), as well as phosphorylation of AMPK, was increased in WAT (but not in BAT) of RH-fed mice.
CONCLUSIONS:

Taken together these results indicate that dietary rose hip prevents body weight gain by increasing whole body EE and inducing browning of WAT. Thus, it has potential therapeutic implication for treatment of obesity and related metabolic disorders.
KEYWORDS:

Browning; Diet; Energy expenditure; Obesity; Rose hip

PMID:
27980600
PMCID:
PMC5139088
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Some good reading here sir, thanks for sharing. Can't wait for BMP with RH to show up :)
 
shockrock3 said:
Some good reading here sir, thanks for sharing. Can't wait for BMP with RH to show up :)
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I finally got acknowledgement on the order. Looking at 2 weeks!!

This makes me VERY happy. However, with the amount of ingredients I have left without putting in a full order, I only have enough for about 300 pouches.
 
dsade said:
I finally got acknowledgement on the order. Looking at 2 weeks!!

This makes me VERY happy. However, with the amount of ingredients I have left without putting in a full order, I only have enough for about 300 pouches.
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raises hand.... i'm in
 
dsade said:
I finally got acknowledgement on the order. Looking at 2 weeks!!

This makes me VERY happy. However, with the amount of ingredients I have left without putting in a full order, I only have enough for about 300 pouches.
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Please make sure to save some for people that ordered months ago :)
 
ax1 said:
Please make sure to save some for people that ordered months ago :)
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I'm pulling aside 50 pouches just in case.
 
Woody said:
Any issue with taking 3 doses at once instead of split 3x a day

Besides the awful taste lol
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IMO it would be a waste. Now these are supplements designed to increase expression of these proteins so that should be a limiting factor, but there have been studies showing mega doses of the actual BMPsbhaving potential for carcinogenesis.

But, mostly it would be an expensive waste.
 
dsade said:
IMO it would be a waste. Now these are supplements designed to increase expression of these proteins so that should be a limiting factor, but there have been studies showing mega doses of the actual BMPsbhaving potential for carcinogenesis.

But, mostly it would be an expensive waste.
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So it's better to split the doses evenly through the day than take all at once? Dosage would be the same. (3 scoops at once vs 1 scoop 3x a day).

I may have my dosing wrong. I wrote it down about 3 months ago but never started until now. Have 3 bags I wanna take for a spin
 
Yep...1 acooop 3 times per day with 1 dose around workout.
 
GreenMachineX said:
I thought it was twice a day?
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I gotta be honest...I'm going on 6 straight days of 12-14 hours a day and I got about 45 minutes of sleep last night. I'm straight up loopy.

Someone pass the meth.
 
dsade said:
Now these are supplements designed to increase expression of these proteins so that should be a limiting factor, but there have been studies showing mega doses of the actual BMPsbhaving potential for carcinogenesis.
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dsade question related to this comment. Recombinant BMP-7 has been shown in some animal studies to slow and even reverse kidney fibrosis in both acute and CKD. For nearly two decades various pharma companies have bought and sold the patents. Each time with press release about how this could revolutionize CKD treatment. And the after a few years it's sold yet again. Think this may be because each time they figure out high doses can cause cancer so they sell it to the next guy? Or maybe they do the math and figure out more money made in transplants and a lifetime of immunosuppressants?

At any rate. I'm fascinated with BMPs especially BMP-7 and have been following your product as a natural way to increase expression. Curious of your thoughts (after you get some rest of course)
 
Tank999 said:
Is the new run gonna have the anti clumping agent?
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Yeah, since I had to throw away the labels with the bakuchiol, the next batch will have ghetto labels, and will including anti-clumping.
 
AndrewMcD said:
What's the ETA on when we can buy BMP again?
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PO was acknowledged today, which means everything should ship by the end of the week. Once I get tracking it will go up for sale- probably the end of next week.
 
Here's one

Invalid Link Removed
 
dsade said:
Here's one

Invalid Link Removed
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Thank you! I need to get my hands on a couple bottles and try it out. I've been meaning to expand my Evomuse products that I've used because they all look so promising, but I think BMP would be a good for me right now.
 
We'll have the powder back in stock first, in about 3. Weeks.
 
Max32 said:
Matt, will there be a pre-order/sale?
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No until I have the tracking number in hand that shows that it has cleared customs. I'm tired of my reputation being damaged by the actions/inactions of others when we plan and execute a presale.
 
Could this also have a healing effect on joint issues? I'm trying to see where all to put my money and if I could possibly save on a joint product then that means more money for the fun stuff. Lol
 
rascal14 said:
Could this also have a healing effect on joint issues? I'm trying to see where all to put my money and if I could possibly save on a joint product then that means more money for the fun stuff. Lol
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There is some crossover, but BMP 2, 4, and 7 (mostly 2 and 7) influence bone and muscle development. Once things calm down a little more here and I am really able to dig into the highly complex world of BMP/SMAD complexes then I'm going to start work on the EvoMuse joint formula.
 
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