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Erase week 3. Holy joint pain !

Its been used while on test, but not dbol AFAIK.

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I was hoping it would be...ive never run dbol but heard the E sides get pretty nasty without aromisin or Adex....thought I could get away with OTC....we will see what Natty has to add in
 
Rosie Chee Scott said:
Cissus actually DOES help manage cortisol; in fact it "Suppresses cortisol and promotes nutrient delivery into connective tissue" - hence why it is so good for joints as well. If you read the appnut.com/files/7613/0860/2375/Osteobolin-C_Tech_Write_Up.pdf Technical Write-Up for Osteobolin-C it explains everything, as well as providing various studies referenced from. Or do a quick Google [Scholar] search - you're bound to find a lot of information.

~Rosie~
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I didn't find any studies actually showing that Cissus lowers cortisol systemically. The only articles I saw on google scholar relating cissus with systemic cortisol were product write-ups for USP and LG Sciences products.

However it is known that cortisol plays an important role in joint health. For example in this study, cortisol injections in rats increased tendon strength and flexibility, but decreased strength at the bone attachments, suggesting that joint health is governed by a complex interaction of many hormones and nutrients: informahealthcare. com/doi/abs/10.3109/17453678008990791

Maybe I was wrong to suggest that increased cortisol = better joints, but conversely I DEFINITELY think it's incorrect to say lower cortisol = better joints.

As far as I know, the actual MOA of cissus is unknown and most support is anecdotal. Does anyone know of any double blind studies relating cissus to cortisol or joint health?
 
nattydisaster said:
Usually the only joint pain is when people take 3 per day.
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I seem to be doing fine thus far on 3 a day, but I am just wondering why the side effect is pain in joints specifically and not something else, like, say, ears changing shape or something, well, not literally, of course, but you get the idea?
 
Flabby said:
Maybe I was wrong to suggest that increased cortisol = better joints, but conversely I DEFINITELY think it's incorrect to say lower cortisol = better joints.
Click to expand...

Neither I (or any one else) one said that lower cortisol = better joints. The quote referring to Cissus' cortisol managing properties and benefits on joints does not mean that those factors are correlated.

~Rosie~
 
Rosie Chee Scott said:
Cissus actually DOES help manage cortisol; in fact it "Suppresses cortisol and promotes nutrient delivery into connective tissue" - hence why it is so good for joints as well.
Click to expand...

Rosie Chee Scott said:
Neither I (or any one else) one said that lower cortisol = better joints. The quote referring to Cissus' cortisol managing properties and benefits on joints does not mean that those factors are correlated.
Click to expand...

Huh?

I also searched on google scholar like you recommended and found nothing to back up any relationship between cissus and cortisol. If there's something to support a relationship between cissus and cortisol can you please link it?
 
Flabby said:
I didn't find any studies actually showing that Cissus lowers cortisol systemically. The only articles I saw on google scholar relating cissus with systemic cortisol were product write-ups for USP and LG Sciences products.

However it is known that cortisol plays an important role in joint health. For example in this study, cortisol injections in rats increased tendon strength and flexibility, but decreased strength at the bone attachments, suggesting that joint health is governed by a complex interaction of many hormones and nutrients: informahealthcare. com/doi/abs/10.3109/17453678008990791

Maybe I was wrong to suggest that increased cortisol = better joints, but conversely I DEFINITELY think it's incorrect to say lower cortisol = better joints.

As far as I know, the actual MOA of cissus is unknown and most support is anecdotal. Does anyone know of any double blind studies relating cissus to cortisol or joint health?
Click to expand...

If you search the USPlabs forum, they dealt with that question in the past.
The Study compared the keto sterones to durabolin for it's Antiglucocorticoids properties.

It was done in dogs....
 
kjkriston said:
I was hoping it would be...ive never run dbol but heard the E sides get pretty nasty without aromisin or Adex....thought I could get away with OTC....we will see what Natty has to add in
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Erase is used heavily with all the legal designer steroids...so....there is your answer. Im sure people have used it with dbol. Its an AI and its the real deal.

I would use Erase over chugging those mis-dosed PEG400 loaded research chemicals. Gross.

John33 said:
I seem to be doing fine thus far on 3 a day, but I am just wondering why the side effect is pain in joints specifically and not something else, like, say, ears changing shape or something, well, not literally, of course, but you get the idea?
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It is just dryness in particular. You will notice more frequest urination the first few days and a more dry appearance overall. The dryness, when it becomes too much, is first felt in your joints

USProduct-Edu said:
If you search the USPlabs forum, they dealt with that question in the past.
The Study compared the keto sterones to durabolin for it's Antiglucocorticoids properties.

It was done in dogs....
Click to expand...

What's a good dose of cissus for my dog?


Kidding!

I have used Cissus RX in the past with great success. I even had an entire college baseball team taking it back when it released because it worked wonders on my shoulders. It will be a staple if I ever have time to hit the gym heavyweight style again
 
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