I am not good and reading this stuff it goes way over my head but from reading chapter 17 on "Estrogens and male reproduction" All through reading this I find that Erections are liked to E2 and E2 is found in the Penis. This for me was dam hard to focus on and I would put in more cut & pastes but this site only allows so little in a post.
But for me and I may be wong getting E2 at the right levels brings back morning erections and stops ED in men.
Phil
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Recently, estrogen receptors have been identified in the corpus cavernosum suggesting also a possible involvement of estrogen in the local mechanism of erection (136). Thus, a possible indirect effect of testosterone through the activation of the aromatase pathway may be possible also in the penile tissue.
Advances in the understanding of the role of estrogens in animal and human models suggest a role for this sex steroid in the reproductive function of both sexes. The fact that both estrogen excess and estrogen deficiency influence male sexual development, testis function, the hypothalamic-pituitary-testis axis, spermatogenesis and ultimately male fertility highlight the importance of estrogen action in the male. From an evolutionary perspective this provides an example of the parsimony operating in biological events that are crucial for the evolution of the human species such as growth and reproduction.
This chapter has been concerned with the reproductive effects of estrogens in males but there are emerging roles for estrogens in non-reproductive tissues. In particular, while traditionally, testosterone has been considered the sex hormone involved in bone maturation and growth arrest in men, but recently the key role of estrogens on growth has been emphasised (5, 49). In men and women, in fact, epiphyseal closure and growth arrest are not achieved without estrogens, underlining the fact that estrogens on human growth are highly conserved in both sexes. Thus it is clear that testosterone might act directly or through its conversion into estrogens (124). This aspect of estogen action is discussed in Chapter 2 and Chapter 3 in this section.
