The Stand is one of their biggest influences.
Carlton Cuse: For us, The Stand has been a model. Lost is about a bunch of people stranded on an island. It's compelling, but kind of tiny. But what sustains you are the characters. In The Stand, I was completely gripped by everyone you introduced in that story — how they come together, what their individual stories are, how they face the premise. That was such a good model for Lost.
Lindelof: The first meeting I had with J.J. about Lost, we talked about The Stand, and it kept suggesting ideas throughout the process. The character of Charlie was always going to be a druggie rocker, but when Dominic Monaghan came in to audition we started saying, ''What if he was a one-hit wonder?'' I said, ''Like the guy in The Stand! The guy with just this one song.''
Lindelof: His entire character sort of is constructed around that. The thing about The Stand is that there are all the archetypes, and we embraced the same thing. The strong, silent, heroic type. The nerdy guy. The techie. The pregnant girl. All those characters exist in The Stand, too.
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(woohoo, i can finally post links and pictures!)
Another good quote about the nature of the show relating to it:
Damon Lindelof: It actually IS liberating... but at the same time, the show constantly forces us to evolve. We CAN'T go back to the ambiguity of Season One because our characters have experienced so much since then. Carlton and I often talk about the STAND... how the story starts with something scientific, an epidemic that kills of 99% of the world's population... but slowly and steadiy transforms into a mystical tale where people are having prophetic dreams... and finally, LITERALLY ends with the hand of God coming out of the sky and setting off a nuclear device. Our story has always been about a journey... but just because we're embracing some of the more fantastical aspects of the island, doesn't mean we're completely abandoning the science vs. faith of it all.
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From 2009, so don't read if you haven't been watching the show up till now unless you don't care about being spoiled.
I've always meant to read The Stand, but never got around to it. I did check out King's first few Dark Tower books (which the Lost creators also seem to be fond of) but never finished the whole series. I heard that that is for the better though, as the way that series of books end is pretty lame.