Anyone taken Prolactrone or another L-DOPA supp? Sides?

conkertheking

Member
Hey, I'm considering taking Prolactrone shortly for an unbelievably irritating prolactin issue I have. It's one of the few supplements which is easily available OTC for me (I'm in Ireland, they literally ban absolutely everything here eventually) and looks very promising.

What's preventing me from taking the plunge is a lot of literature I've found online which talks about the side effects of L-DOPA including some fairly horrific sounding ones involving loss of muscle control (dyskinesia) etc. However, all of those studies are based on people who were already suffering from Parkinson's Disease (and in a rather advanced stage, I gather) which I can't help feeling doesn't necessarily translate in terms of how it might adversely affect a relatively healthy young adult without PD or any related disorder.

So with that in mind, just wondering has anyone taken this product (or a similar one) and if so, what were the sides if any?

And does anyone have any bloodwork to show its effect on prolactin levels? I've heard there are a few floating around but I can't seem to find any.

(Note: I've never taken Tren or indeed any other prohormone, I seem to be just cursed with an appalling hormone profile. After two blood tests, one showed everything within the "normal" range, but at the extreme end of normal such that apparently someone looking at my bloods would have assumed I was in my eighties had I not told them I was 25! Ergo while any experiences are appreciated, I'm particularly interested in those who've taken products standalone rather than as part of PCT.)
 
As far as I-dopa I never had any sides other than an occasional headache but it went away after continued use. It's a pretty safe supp so I wouldn't worry about that.

However if you have a prolactin problem naturally and not from using any supplements that would be more of my concern. It's not just a temporary spike caused by a supplement that another supplement can bring back to "normal range." It sounds like you have more of an underlying issue. Try the supplement and see if it helps but you may also want to try and get to the root of the problem.
 
Afi140 said:
As far as I-dopa I never had any sides other than an occasional headache but it went away after continued use. It's a pretty safe supp so I wouldn't worry about that.

However if you have a prolactin problem naturally and not from using any supplements that would be more of my concern. It's not just a temporary spike caused by a supplement that another supplement can bring back to "normal range." It sounds like you have more of an underlying issue. Try the supplement and see if it helps but you may also want to try and get to the root of the problem.
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I'll explain my reasoning in a bit if there are any other replies, don't want to hijack the thread but I have specific reasons for being interested in both suppressing prolactin and increasing dopamine, namely the fact that I have zero motivation for anything at the moment except in very brief bursts after workouts for which I take Animal Pump, which is full of stimulants. That alone points to prolactin / dopamine issues as far as I'm concerned, even before taking into account my crappy blood results.

As I say I'm in an experimental mood and I'll give supps a shot, but not if they're going to permanently **** me up. Few scare stories about L-DOPA are making me think twice, but on the other hand I'd much rather follow the advice of AB users than Redditors :p
 
To add to the above, I don't particularly understand how an amino acid which is actually produced by the body can be responsible for such horrific and permanent disability if taken as a supplement in reasonable amounts - seems like scare mongering to me, unless I'm missing something. As I say, as all of the major studies highlighting the armageddon like effects of L-DOPA are based on patients already suffering from a disease which severely alters brain chemistry, I'm not sure how relevant they are to healthy individuals?
 
koi1214 said:
brundel halfhuman or kisaj can answer all your questions about Prolactrone.
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Been talking a lot to Brundel about it, great guy and definitely going to give it a try, just thought I'd look for some opinions from average punters as well as industry folk :D

Sounds like the side effects were massively overblown anyway though so should be good.
This was the thread which spooked me:
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As I say, seems like hyperbole and relying on studies which are only applicable to Parkinsons' patients. But just want to be as informed as possible.
 
L-dopa can put me to sleep, keep me awake..it's hit and miss. I can't take it before bed or during the day for these reasons.
 
conkertheking said:
Hey, I'm considering taking Prolactrone shortly for an unbelievably irritating prolactin issue I have. It's one of the few supplements which is easily available OTC for me (I'm in Ireland, they literally ban absolutely everything here eventually) and looks very promising.

What's preventing me from taking the plunge is a lot of literature I've found online which talks about the side effects of L-DOPA including some fairly horrific sounding ones involving loss of muscle control (dyskinesia) etc. However, all of those studies are based on people who were already suffering from Parkinson's Disease (and in a rather advanced stage, I gather) which I can't help feeling doesn't necessarily translate in terms of how it might adversely affect a relatively healthy young adult without PD or any related disorder.

So with that in mind, just wondering has anyone taken this product (or a similar one) and if so, what were the sides if any?

And does anyone have any bloodwork to show its effect on prolactin levels? I've heard there are a few floating around but I can't seem to find any.

(Note: I've never taken Tren or indeed any other prohormone, I seem to be just cursed with an appalling hormone profile. After two blood tests, one showed everything within the "normal" range, but at the extreme end of normal such that apparently someone looking at my bloods would have assumed I was in my eighties had I not told them I was 25! Ergo while any experiences are appreciated, I'm particularly interested in those who've taken products standalone rather than as part of PCT.)
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Inhibit P is always another option as well. Good luck on your future run, I am sure either product will give you desirable results naturally.
 
fightbackhxc said:
Inhibit P is always another option as well. Good luck on your future run, I am sure either product will give you desirable results naturally.
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Well we'll see, I'm prepared to give caber or prami a shot if it becomes absolutely unavoidable but as with gyno surgery I feel exhausting every milder option first makes more sense.

On Inhibit-P, apart from it not being locally available like Prolactrone, I've always felt it seemed a little contradictory as it combines vitamin B6 with an L-DOPA extract - doesn't this cause L-DOPA to be metabolized in the periphery as b6 doesn't cross the blood-brain barrier? The advice I've heard pretty much universally is to avoid mixing the two supplements at all costs, hence my confusion over Inhibit-P's formula. Anyone got clarification on this? Prolactrone involves a decarboxylase inhibitor which helps it to avoid peripheral conversion but b6, from all accounts, aids peripheral conversion...?
 
You could also look into Dopadex which is almost pure L-dopa. Similar to prolactrone but without the EGCG. EGCG isn't a clinically significant decarboxylase inhibitor unfortunately unless consumed at ~5 grams, but prolactrone will still work because l-dopa works so either bet is fine.
 
Dopadex does wonders for prolactin control.
 
conkertheking said:
Well we'll see, I'm prepared to give caber or prami a shot if it becomes absolutely unavoidable but as with gyno surgery I feel exhausting every milder option first makes more sense.

On Inhibit-P, apart from it not being locally available like Prolactrone, I've always felt it seemed a little contradictory as it combines vitamin B6 with an L-DOPA extract - doesn't this cause L-DOPA to be metabolized in the periphery as b6 doesn't cross the blood-brain barrier? The advice I've heard pretty much universally is to avoid mixing the two supplements at all costs, hence my confusion over Inhibit-P's formula. Anyone got clarification on this? Prolactrone involves a decarboxylase inhibitor which helps it to avoid peripheral conversion but b6, from all accounts, aids peripheral conversion...?
Click to expand...

I believe this has been addressed multiple times on AM. For more reference see this thread.

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My reading of it is that peripheral conversion of dopamine might be partly responsible for reducing prolactin, hence B6 aiding prolactin suppression, while conversion in the brain is what leads to dopamine's psychological effects (risk taking, reward seeking, etc)

If that's the case, wouldn't the best thing to do be to take the three caps of Prolactrone daily, and then take something like ZMA at night so that some would be affected by the B6 but not all? To be honest, I'm having such motivation issues at the moment that I wouldn't say no to both inhibiting Prolactin and increasing my dopamine levels in the brain - case in point, when I take Animal Pump on workout days (which is full of caffeine and other stimulants) I'm much more motivated when it comes to writing, playing music and stuff like that, and I'm assuming this is partly because caffeine causes a brain dopamine spike - so by my thinking, you want a mixture of a little peripheral conversion and a fair amount of BBB crossing as well, no?

EDIT: I suppose what this comes down to is whether the mood-enhancing effects of dopamine (motivation, sex drive etc) are more down to its effects inside the brain or its effects elsewhere in the body. Does anyone have any further info on this? Sources are very conflicting.
 
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