The worry with igf lr3 is that its affinity doesn't really differentiate between muscle, bone, intestinal, etc cell types. Depending on many factors only so much of the igf can be absorbed by each muscle. I have read studies both supporting and negating the benefits of receptor affinity immediately post workout, but I like the idea. According to some studies the period about 15 minutes post workout, some say even less, the muscle you worked has a much increased receptor affinity to igf. So my theory was you spot inject, being subcutaneous, the muscle would have a higher absorption wherever injected. Using smaller doses is more economical and also would hopefully leave little igf to be circulated to other tissues. The reason I say it worked well is 1) No side effects, it is now 4 years later and still no sides typically associated with use. 2) Fat loss equivalent to much higher doses some other people have used. 3) Increased injury recovery, one guy had his knee done. 4) Strength continued to increase even after a full pct and then being off aas for over 2 months.