Reading through some of the literature on this stuff now. Here’s a promising study for those interested: Invalid Link Removed
It seems the biggest improvement in those training in the high dose ginsenoside group was increased aerobic endurance. Main side effect was allergy type symptoms/itchiness.
Only thing that keeps getting my attention is the mg for high standardizations. The “high dose” group in the study was given 500mg of ginsenoside per day, but it was standardized to 10.01%. That would only come out to 50mg of a 100% standardization. Similarly, there’s some other studies showing humans only given 5 pure mg of Rg1: Invalid Link Removed & Invalid Link Removed
Guess I’m wondering where you landed on 400mg of 98% standardization and what the rationale is there? Thanks.
Yup there is actually more evidence that Ginsinosides are anabolic than pretty much any natural anabolic i have ever seen.
This includes Epicatechin, Laxogenin etc etc etc etc.
Also that they improve performance, strength, fat loss.
Basically they are not far off from a naturally present steroid. An analogue for certain.
And you are right there are studies regarding the ginsinosides and Echinacosides using very small doses orally in humans.
Interestingly while bioavailability is variable and relatively low with the ginsenosides its next to 0 with the echinacoside.
A cistanch extract by itself would yield basically no uptake of the intended compounds.
And there are very specific reasons why.
I think some people think that you can just add piperine to anything and its magically got great bioavailability but this just isnt so. There are MANY reasons why things are not well absorbed or utilized and in some cases there are multiple for one substance.
It took alot of tinkering to make this work. And......the end product is exceptionally expensive to make.
There is much more than aerobic endurance. Just from RG1 studies=
"Rg1 improves muscle functionality via enhancing muscle gene expression and oxidative
muscle metabolism"
"
Rg1 upregulates promyogenic kinases, especially Akt, resulting in improvement of myoblast
differentiation and myotube growth:"
"
Rg1-treated mice exhibited significantly
elevated grip strength, as assessed by the grip test. These results suggested that
Rg1 treatment increased myofiber size and elevated muscle
strength. "
There are many more. And again this is just one of the actives.