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Anabolic Pump -- A Review by bitterplacebo

well darn, i suppose i'll have to keep an eye out on the supplement auction then to see if i can swap something for some AP (as daycare costs are killing me). i think i have 6 or 8 caps left, i'll try out using them pre fasted workouts at least, should last a couple weeks that way
 
bitterplacebo said:
I think you still need to manipulate your CHO intake pre-WO to take advantage of it's MOA, but only in the case that you are an HSP and also an LSBD that recently visited PP on a HTB.
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In reality, CHO is not necessary pre-wo. What you need is PRO, which has been scientifically proven to increase protein synthesis as well as other benegits.

Need I remind people that there is no such thing as an essential CHO, but there are essential-aa's and essential-efa's.

And unless you are an endurance athlete, the CHO's are not needed IMHO.
 
Ares said:
In reality, CHO is not necessary pre-wo. What you need is PRO, which has been scientifically proven to increase protein synthesis as well as other benegits.

Need I remind people that there is no such thing as an essential CHO, but there are essential-aa's and essential-efa's.

And unless you are an endurance athlete, the CHO's are not needed IMHO.
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I feel this to be more or less incorrect. CHO intake is of paramount to athletes of all types, for a few primary reasons. Firstly, glycogen depletion is the primary cause for muscular fatigue (see: processes of glycolysis being necessary for ATP provision; secondly, proper intake and timing of CHO is also of primary concern to mediate the transfer between energy producing (catabolic) to energy consuming (anabolic) processes, post training (resistance training, especially); thirdly, it is well documented that muscle protein synthesis is stimulated in the post-training environment by the Insulin pathway, and the most advantageous post-training regime is the fusion of carbohydrates AND amino acids.

This is especially pertinent to bodybuilders, as our training methodology focuses heavily on the eccentric portion of the lift; there is myriad data supporting the necessity for optimal CHO intake pre/post workout, due to the increased rate at which eccentric exercises diminishes glycogen synthesis Post-WO. Rather than regurgitate results, this is an interesting study which more or less verifies the necessity for Pre/Intra/Post-WO Carbohydrate supplementation:

Haff GG, Lehmkuhl MJ, McCoy LB, Stone MH. “Carbohydrate Supplementation and Resistance Training.” Journal of Strength and Conditioning Research, 2003 Feb; 17(1): 187-196.
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This study is especially relevant, as it reviews 70 (I believe, cannot remember) datum pieces of original research, and concludes the optimal approach is Pre/Intra/Post WO CHO for the above mentioned reasons.
 
Mulletsoldier said:
No, I would suggest against it. AP is applicable in that sense because it inhibits cellular respiration, and therefore allosterically activates AMPk; AMPk is the primary anti-lipolytic in AP, and achieves this through several very interesting mechanisms! In short, it vastly increases the hydrolyzation of stored WAT, and subsequent mitochondrial B-Oxidation of FAs/TGs. That achieves two effects, pertinent to our lifestyle:

a) Increased strength and stamina, as FA oxidation comprises 2/3 of the cellular energy transactions involved in resistance training.

b) Reduced adiposity.
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(1) I don't understand AP containing an anti-lipolytic. Doesn't that mean it prevents the breakdown of fat? While this might explain my results, I don't think I'm understanding this part completely right. edit: I just looked up AMPk, it sounds pretty lipolytic, did you typo?
(2) I don't know WTF all these acronyms mean all the time, which I was joking a little about in my previous post. I can make educated guesses, like for FA & MOA. I can use the google, but unfortunately not everything comes up so cleanly like WAT. I'm also afraid google is beyond the scope of some people. May I request a key?
 
bitterplacebo said:
(1) I don't understand AP containing an anti-lipolytic. Doesn't that mean it prevents the breakdown of fat? While this might explain my results, I don't think I'm understanding this part completely right. edit: I just looked up AMPk, it sounds pretty lipolytic, did you typo?
(2) I don't know WTF all these acronyms mean all the time, which I was joking a little about in my previous post. I can make educated guesses, like for FA & MOA. I can use the google, but unfortunately not everything comes up so cleanly like WAT. I'm also afraid google is beyond the scope of some people. May I request a key?
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Apologies; I'm ridiculously tired and I meant anti-lipogenic and lipolytic.

WAT = White Adipose Tissue, and is the primary source of adipose tissue in humans. It is differentiated from BAT (brown adipose tissue) by both the roles it plays in the body, and its energy demands.
 
bitterplacebo said:
(1) I don't understand AP containing an anti-lipolytic. Doesn't that mean it prevents the breakdown of fat? While this might explain my results, I don't think I'm understanding this part completely right. edit: I just looked up AMPk, it sounds pretty lipolytic, did you typo?
(2) I don't know WTF all these acronyms mean all the time, which I was joking a little about in my previous post. I can make educated guesses, like for FA & MOA. I can use the google, but unfortunately not everything comes up so cleanly like WAT. I'm also afraid google is beyond the scope of some people. May I request a key?
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All the l33t folks talk in acronyms...

In addition, when presenting an acronym for the first time one should define it in parenthesis...but hey if you don't want people to follow along, use as many acronyms as possible.
 
Ares said:
All the l33t folks talk in acronyms...

In addition, when presenting an acronym for the first time one should define it in parenthesis...but hey if you don't want people to follow along, use as many acronyms as possible.
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Well, considering the point was to elaborate upon the product, the explicit intent was for people to follow along; easy mistake, though.

:)
 
so as a thought on the fasted cardio dosing style, does it then also make sense to the use the AP as a prebed as well?
 
EasyEJL said:
so as a thought on the fasted cardio dosing style, does it then also make sense to the use the AP as a prebed as well?
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In the pre-bedtime sense, you would enter your body into gluconeogenesis; not a good state to be in while you sleep. In the pre-workout sense, gluconeogenesis is a foregone conclusion, so it cannot and should not be avoided.
 
So the lipolytic wouldn't partcularly effect that? what if i regularly am taking either bcaas or casein (whether from powder or cottage cheese) prebed as well? Just trying to work thru the best usage of the lipolytic portion
 
Mulletsoldier said:
In the pre-bedtime sense, you would enter your body into gluconeogenesis; not a good state to be in while you sleep. In the pre-workout sense, gluconeogenesis is a foregone conclusion, so it cannot and should not be avoided.
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Yes at bedtime seems like it would leave your body in a bad state.
 
Mulletsoldier said:
In the pre-bedtime sense, you would enter your body into gluconeogenesis; not a good state to be in while you sleep. In the pre-workout sense, gluconeogenesis is a foregone conclusion, so it cannot and should not be avoided.
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This is unclear, so let me elaborate further:

As you wake in the morning, your body has just undergone an eight hour bout of starvation - literally; in this sense, the broader processes of Ketosis have already begun: Your body has begun hydrolyzing stored adipose to produce glycerols and fatty acids, and they cycle the bloodstream serving as the source of fuel throughout the night. When you awake, you can either choose to utilize these as a source of currency in anaerobic energy transactions, or allow them to redeposit.

Using Anabolic Pump at this time is beneficial in three sense; a) it prevents the synthesis of both triglycerides and fatty acids, necessarily causing your body to oxidize those FAs/TGs circulating as the result of your fast; b) it prevents the accumulation of said TGs/FAs (meaning they will not redeposit i.e., can be used as fuel); and c) it directly regulates the mechanisms responsible for the mitochondrial b-oxidation of fatty acids! Therefore, AP in conjunction with a chronic fasted state = Ketosis; literally! All the benefits of Ketosis, while not completely sacrificing carbohydrates. As B5150's log can attest to, this means: Increased stamina, increased strength, and a euphoric feeling (b-oxidation can regulate Dopaminergic/Serotonergic synthesis).

Now, this is not applicable to pre-bedtime, as the MGU (muscle glucose uptake) capacities of Anabolic Pump will preemptively place your body in a glucose deprived state; especially, if you do not consume carbohydrates prior to bed (which I believe is the insinuation here). As a result, the process of gluconeogenesis will occur, leading to unwanted physiological repercussions.
 
could any type of catabolism be triggered in any way by putting your body into this state when going to sleep for the night??
 
RoadBlocK said:
could any type of catabolism be triggered in any way by putting your body into this state when going to sleep for the night??
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I believe you mean by ingesting AP sans carbohydrates? If so, then yes. Gluconeogenesis is necessarily catabolic, but not in the tissue destructive sense. While catabolic is a catch-word in the industry, it literally means "energy producing". In fact, your body becomes catabolic while you are involved in resistance training; in only becomes anabolic after.
 
Well, Im just trying to keep up with the group, you've got the lock on the science, but my question was about the liver making glucose from other sources when carbs/glycogen stores are depleted, converting/stealing aminos to keep a constant blood glucose level, and I was just curious if throwing yourself into this depleted state could possible affect muscle tissue, even for such a brief period as 8 hours.

AND, check your PM-s please.
 
Mulletsoldier said:
This is unclear, so let me elaborate further:

As you wake in the morning, your body has just undergone an eight hour bout of starvation - literally; in this sense, the broader processes of Ketosis have already begun: Your body has begun hydrolyzing stored adipose to produce glycerols and fatty acids, and they cycle the bloodstream serving as the source of fuel throughout the night. When you awake, you can either choose to utilize these as a source of currency in anaerobic energy transactions, or allow them to redeposit.
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It hadn't quite crossed my mind before, but an immediately upon rising Salvia Miltiorrhiza dose would make good sense as well.
 
RoadBlocK said:
Well, Im just trying to keep up with the group, you've got the lock on the science, but my question was about the liver making glucose from other sources when carbs/glycogen stores are depleted, converting/stealing aminos to keep a constant blood glucose level, and I was just curious if throwing yourself into this depleted state could possible affect muscle tissue, even for such a brief period as 8 hours.

AND, check your PM-s please.
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Yes, exactly; Gluconeogenesis. That is why it is beneficial PRIOR to working out after a fast, but not PRIOR to bedtime!

:)
 
EasyEJL said:
It hadn't quite crossed my mind before, but an immediately upon rising Salvia Miltiorrhiza dose would make good sense as well.
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If your goal is tissue recomposition Easy, this would be my suggestions:

Pre-Bed:
High Protein
High Fat (moderate amount of saturated fats)
Low Carbohydrate

Upon Waking:
1 AP (or 2, depending on tolerance)
Salvia or other lipolytic agent which directly hydrolyzes adipose (need fat store liberation)
Caffeine

15 minute later:
Resistance training

On last set:
1 AP (preferably P-Slin)

In that respect, you are upregulating the b-oxidation of FAs (fatty acids), preventing their synthesis, as well as preventing their accumulation! Subsequently, you have a veritable 'jackpot' of FAs/TGs to utilize, in order to provide very startling amounts of energy. As well, a further benefit on physique, is that redepositing is highly unlikely, as AMPk prevents such processes for up to 6 hours!
 
do i have this right?

bp reported he had a poor response to ap while taking it as directed.

so it is now suggested that he purchase another bottle and try running it without carbs?
 
Hank Vangut said:
do i have this right?

bp reported he had a poor response to ap while taking it as directed.

so it is now suggested that he purchase another bottle and try running it without carbs?
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Hank,

I know you have no ill-intentions, but please do not paint me in that light. Somebody happening upon this thread will immediately accuse myself and/or USP Labs of badgering non-response customers.

BP merely stated the product did not work for him, and I gave possible alternative suggestions as to what he could have done had he contacted me prior. Definitely not suggesting he purchase another bottle by any means.
 
in skimming the past couple pages of this thread it just caught me off gaurd, as i wasn't aware of the ap without carbs protocol.

i know you said brian had good results with this approach.
have you seen others positive reports of people using ap w/o carbs?
 
Hank Vangut said:
in skimming the past couple pages of this thread it just caught me off gaurd, as i wasn't aware of the ap without carbs protocol.
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Definitely a new approach! As I said, I know you mean no ill intent, I merely wanted to clarify I was not badgering BP.

i know you said brian had good results with this approach.
have you seen others positive reports of people using ap w/o carbs?
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Yes, quite a few individuals whom I have personally guided with this approach have had success! In fact, I happened upon the practical application of this approach while at the GNC Franchise Exposition: I dosed my Anabolic Pump, under the impression we were eating very soon, and we did not eat for quite some time! As a result, I trained in the interim, and had fantastic stamina and pumps.

I then began to investigate exactly why that protocol was so successful, and came up with Brian's approach. That being said, Brian's includes: BCAAs, ReCreate, and PowerFULL. The latter two can be substituted by choice, but I would recommend the BCAAs.
 
there may have been a hint of ill intent in my original post. lol.

when i see someone post negative feedback on ap it is often times followed up with....."you didn't use it right".
discrediting their opinion and placing the blame back on them.

what's wrong with just saying, "not everyone responds"?
to me that seems more logical and doesn’t come across as offensive to the consumer.

i know your intensions are not to badger, you are just trying to help the non-responders respond.
however, this being the first time i had heard of using ap without carbs i believe i mistook your intensions as badgering initially.
 
Hank Vangut said:
there may have been a hint of ill intent in my original post. lol.

when i see someone post negative feedback on ap it is often times followed up with....."you didn't use it right".
discrediting their opinion and placing the blame back on them.

what's wrong with just saying, "not everyone responds"?
to me that seems more logical and doesn’t come across as offensive to the consumer.

i know your intensions are not to badger, you are just trying to help the non-responders respond.
however, this being the first time i had heard of using ap without carbs i believe i mistook your intensions as badgering initially.
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Definitely not; if you read the entire thread, I actually mention several times the OP is merely a non-responder. I had only two intentions; firstly, to mention that individual non-response is not indicative of product quality; secondly, to elaborate on the possibilities for his non-response!

As well, if you review the thread, I said the following which speaks to your skepticism:

Mulletsoldier (in reference to post-AP suggestions) said:
It is somewhat difficult after the fact, and suggesting alternatives may appear as if I am discounting your knowledge and experience.
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In fact, I resisted offering my opinions for the same accusations you are putting forward! That being said, no hard feelings here Hank.
 
How would you dose the AP the rest of the day if using the fasted resistance training route? 15min prior to carb meals, or just the one AP dose prior to resistance? IE, upon waking 1 AP, 15min later workout, 1 AP +pwo nutrition, and then another dose with another carb meal? Or for someone looking to go the fasted route, just one AP in the am?
 
SureShot said:
How would you dose the AP the rest of the day if using the fasted resistance training route? 15min prior to carb meals, or just the one AP dose prior to resistance?
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The two AP doses surrounding resistance training, and then your largest carbohydrate meal.
 
Hank Vangut said:
in skimming the past couple pages of this thread it just caught me off gaurd, as i wasn't aware of the ap without carbs protocol.

i know you said brian had good results with this approach.
have you seen others positive reports of people using ap w/o carbs?
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How about I non-respond my foot up your ass.
 
SureShot said:
Sounds good. with 90+ caps in the bottle it would also help it last longer. Basically a TKD while using AP?! or am I off?
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No, exactly right. As I said, this fasted state essentially expedites the broader process of Ketosis: The hydroylzation of stored triglycaerols in response to chronic glucose starvation; subsequently, the production of Ketone bodies and liberation of Fatty Acids are used as a primary fuel source in the absence of glucose. AP achieves this expediting process via both MGU (muscle glucose uptake) effects, and lipolytic and anti-lipogenic effects.
 
EasyEJL said:
where is the real mullet and what have you done with him? wait on seond thought, nevermind ;)
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I like the new fuzzy one :)
I had follow the previous AP discussions re: AP w/out carbs because I found it ironic how initially when people didn't respond to AP we kept telling them they needed to eat more carbs, and then this new protocol came about. There is some good thinking behind it, but personally I'll use my AP with carbs because I think that lets me get the most for my $$. But it's nice to know there's alternate uses.
 
Steveoph said:
I like the new fuzzy one :)
I had follow the previous AP discussions re: AP w/out carbs because I found it ironic how initially when people didn't respond to AP we kept telling them they needed to eat more carbs, and then this new protocol came about. There is some good thinking behind it, but personally I'll use my AP with carbs because I think that lets me get the most for my $$. But it's nice to know there's alternate uses.
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If utilizing Anabolic Pump in its most native and intended approach facilitates the most personal success, most definitely continue; however, this is an alternative for non-responsive customers, wishing to expand their understanding of Anabolic Pump's potential applications!
 
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