I’d take a break and see if that fixes the issue, that way you can isolate the problem.
I don’t know if there’s an actual medical link, but I’ve seen it suggested that overactive choline can lead to depression. I’ve never experienced it, but I do see how it’s possible. From what I know, a lot of neurotransmitters follow inverse relations with others, but definitely with dopamine and acetylcholine. That might be the issue.
I don’t want to give medical advice, but if it was me, I’d probably try a big dose of tyrosine. Not like in an amino blend, other aminos, especially BCAAs can compete with and deplete tyrosine. I’d go at least 3 grams of tyrosine without any other aminos or protein nearby.
In the long term, I’d take tyrosine with your acetylcholine boosters to try and offset this effect. Both will have benefits for workouts or anything requiring mental energy. I’d also be careful with huperzine. It stops the breakdown of acetylcholine, so you can get an excessive buildup. If you want to increase acetylcholine, I’d start with just a choline source so you don’t overdo it. If you want a little more horsepower, I’d add some acetyl carnitine first. From there, you can add huperzine, but again, be very careful. For choline sources, I’d probably lean toward citicoline/CDP choline over alpha GPC, but some people do prefer GPC.
