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11-0X0 , Pro-Anabol, 3-AD

Which will you choose?

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bubsnt3 said:
Pro-anabol is methylated...
"Furthermore, we have added a 17-position methyl ether to increase both the bioavailability and overall potency." (ALRI)
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You left off the following sentence, which would have been very helpful to have included. The only problem with a methylated compound is if it indeed causes liver stress.

"Furthermore, we have added a17-position methyl ether to increase both the bioavailability and overall potency. And a real plus is no liver stress like that realized from use of some of the older pro-hormone products. "
 
macedaddy said:
it may be methylated, but is it hepatoxic? jsut because it is methylated DOES NOT mean it is hepatoxic or unfriendly to the liver............
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I don't know, nor was I implying that it was. I was only correcting the incorrect statement that none of the compounds were methylated....(re-read the post...)
 
rpen22 said:
You left off the following sentence, which would have been very helpful to have included. The only problem with a methylated compound is if it indeed causes liver stress.

"Furthermore, we have added a17-position methyl ether to increase both the bioavailability and overall potency. And a real plus is no liver stress like that realized from use of some of the older pro-hormone products. "
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No I did not need to add that sentence as I was not trying to imply that it was hepatoxic. I did not state anything about this as so many people seemed to have assumed. All that I was saying is, yes, one of these compounds is methylated.... (re-read the post...)
 
bubsnt3 said:
I don't know, nor was I implying that it was. I was only correcting the incorrect statement that none of the compounds were methylated....(re-read the post...)
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i did re-rea dyour post, but what was the intention of saying it was methylated? who cares if it is methylated if we don't know what being methylated means.........

being methylated doesn't prove or say anything..........
 
macedaddy said:
i did re-rea dyour post, but what was the intention of saying it was methylated? who cares if it is methylated if we don't know what being methylated means.........

being methylated doesn't prove or say anything..........
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You are obviouslly way off. Was I trying to say anything about the poduct, no... Did you even read the post that I replied to. I was only trying to help a member by educating him that pro-anabol was a methylated compound.
"being methylated doesn't prove or say anything"
no one said that it did. I was just trying to help.
"who cares if it is methylated if we don't know what being methylated means"
I am pretty sure most people who use these boards know what methylated means. Increased half-life, better oral bioavailability etc..
I hate to say this but you are being rather argumentative and rude over this whole thing. The purpose for me saying that it was methylated was to spread knowledge. I said the other day that PP and ergo were 2 diffferent compounds and I did not get jumped on like this. "what are you saying", "what is the point of saying that". The point is that the information was incorrect and now it is correct. Just admit that you made something out of what it was not ment to be instead of drive an absolutely ubsurd point into the ground.
When I said there was a diff between ergo and PP, I was not trying to say one was better or even explain in any way what correlation that would have to ANYTHING, I was just saying that they were different compounds. I don't know why you think that I had an alterior motive to saying that but assumptions are not the basis on what you should deal with people on. ALL THAT I WAS SAYING IS THAT PRO-ANABOL IS METHYLATED BEINGS IT WAS STATED (SO I THOUGHT) THAT IT WAS NOT. NO MORE NO LESS. IS THIS HARD TO UNDERSTAND??????
 
bubsnt3 said:
No I did not need to add that sentence as I was not trying to imply that it was hepatoxic. I did not state anything about this as so many people seemed to have assumed. All that I was saying is, yes, one of these compounds is methylated.... (re-read the post...)
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I should have used the word hepatoxic instead of methylated I guess, but whenever someone asks about drinking being a problem(liver damage), they're usually asking if it's methylated(hepatoxic) like many of the orals out now are. I understand that you were just correcting me for the sake of correcting me, but the correction really made no difference in the context of the original question IMO.
 
rpen22 said:
I should have used the word hepatoxic instead of methylated I guess, but whenever someone asks about drinking being a problem(liver damage), they're usually asking if it's methylated(hepatoxic) like many of the orals out now are. I understand that you were just correcting me for the sake of correcting me, but the correction really made no difference in the context of the original question IMO.
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Just thought you might like to know(also the people reading this thread might like to know). I think the context of the original question is where people assumed that I was saying that it was hepatoxic. I was trying to educate, not correct(I did not know that you already knew this). In the future if you would not like to know, I can keep my mouth shut; but wow this has ruffled some feathers.
" I understand that you were just correcting me for the sake of correcting me"
If everyone just kept there mouth shut when they saw something out of place, this would not be very educational. Now instead of trying to educate, I was trying to argue or "just for the sake of correction" say that. I would have thought a thank you would have been a fine reply. (I guess I haven't been around long enough..)
 
i thnk your making a bigger deal of this then they bubs.... they are jsut explaining themselves and i think your taking their posts outta context.... these are two usually calm characters and your percieving a diff tone from them then i... just let it be we all know everyones points have been made no need to stir the pot with lingering comments.
 
bubsnt3 said:
Just thought you might like to know(also the people reading this thread might like to know). I think the context of the original question is where people assumed that I was saying that it was hepatoxic. I was trying to educate, not correct. In the future if you would not like to know, I can keep my mouth shut; but wow this has ruffled some feathers.
" I understand that you were just correcting me for the sake of correcting me"
If everyone just kept there mouth shut when they saw something out of place, this would not be very educational. Now instead of trying to educate, I was trying to argue or "just for the sake of correction" say that. I would have thought a thank you would have been a fine reply.
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I'm sorry I hurt your feelings. :)

Anyways, I was not saying you were wrong for correcting me, because I AM admitting I was inaccurate with that statement. I was just saying you could have added the part about it not stressing the liver just to clarify for everyone, as that's what the original question was about.
 
rpen22 said:
I'm sorry I hurt your feelings. :)

.
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IGF-1 maybe?? Estrogen rebound from my cycle??

I will be trying Pro-Anabol first. Does anyone know if a low dose of 3-AD/11-OXO will cause shut down. I would like to run it with my next cutting cycle(I would like to keep this as non-hormonal/suppressive as possible. So far I have this:
WKS 1-2 JW with Clen
WKS 3-4 JW/BAM IGF-1
WKS 5-6 BAM/Pro Anabol Clen
WKS 7-8 Pro Anabol IGF-1
I will also be running cissus the entire time.
I would like to add in some 3-ad/11-oxo for the fat loss effects but I do not want to cause suppression being I will be doing a epi/havoc cycle once this is done. The IGF-1 is also for a tendon injury, IGF-1 works miracles on injuries..
 
poopypants said:
i thnk your making a bigger deal of this then they bubs.... they are jsut explaining themselves and i think your taking their posts outta context.... these are two usually calm characters and your percieving a diff tone from them then i... just let it be we all know everyones points have been made no need to stir the pot with lingering comments.
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I did re-read all the posts and I did make a bigger deal out of it then other people were.
 
Good question. I am not all that familiar with the chemistry behind all of this but isn't the point of methylation to make it harder for the liver to break down? Isn't this what makes the liver enzyme levels raise? If the liver has to work for 12 hours instead of 6(and that now because it is methylated, the liver is the only organ that can break it down so other avenues of metabolism are not able to be used). Or is there somehow a direct impact that certain chemicals have on the liver that others don't?

Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, North Carolina



Partial hepatectomy in the rat results in a large decrease in the rate of demethylation of l-Mesantoin and of trimethadione.

It is concluded that the liver is the principal, if not the only, site of the demethylation of these drugs.

The suggestion is made that the liver is probably the principal site of demethylation not only of N-methyl derivatives of barbituric acid, hydantoin, and 2,4-oxazolidinedione but also of analogous compounds of other chemical types.
 
bubsnt3 said:
Good question. I am not all that familiar with the chemistry behind all of this but isn't the point of methylation to make it harder for the liver to break down? Isn't this what makes the liver enzyme levels raise? If the liver has to work for 12 hours instead of 6 or is there somehow a direct impact that certain chemicals have on the liver that others don't?
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Invalid Link Removed

Methylation is a term used in the chemical sciences to denote the attachment or substitution of a methyl group on various substrates. This term is commonly used in chemistry, biochemistry, and the biological sciences.

In biochemistry, methylation more specifically refers to the replacement of a hydrogen atom with the methyl group.

In biological systems, methylation is catalyzed by enzymes; such methylation can be involved in modification of heavy metals, regulation of gene expression, regulation of protein function, and RNA metabolism. Methylation of heavy metals can also occur outside of biological systems. Chemical methylation of tissue samples is also one method for reducing certain histological staining artifacts. . . .
 
Zombie said:
Invalid Link Removed

Methylation is a term used in the chemical sciences to denote the attachment or substitution of a methyl group on various substrates. This term is commonly used in chemistry, biochemistry, and the biological sciences.

In biochemistry, methylation more specifically refers to the replacement of a hydrogen atom with the methyl group.

In biological systems, methylation is catalyzed by enzymes; such methylation can be involved in modification of heavy metals, regulation of gene expression, regulation of protein function, and RNA metabolism. Methylation of heavy metals can also occur outside of biological systems. Chemical methylation of tissue samples is also one method for reducing certain histological staining artifacts. . . .
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Thank you sir although I think in organic chemistry it is a little different (though I am not sure that it would change anything). This is from the same site.
The term methylation in organic chemistry refers to the alkylation process used to describe the delivery of a CH3 group. This is commonly performed using electrophilic methyl sources - iodomethane, dimethyl sulfate, dimethyl carbonate, or less commonly with the more powerful (and more dangerous) methylating reagents of methyl triflate or methyl fluorosulfonate (magic methyl), which all react via SN2 nucleophilic substitution. For example a carboxylate may be methylated pm pxygen to give a methyl ester, an alkoxide salt RO− may be likewise methylated to give an ether, ROCH3, or a ketone enolate may be methylated on carbon to produce a new ketone.

Can someone tell me how to completely delete a post..
 
I have to bow out gracefully from all of these discussions. I don't even believe that much in overall hepatoxicicity after a cycle is complete.

I would like help though on this question.

I will be trying Pro-Anabol first. Does anyone know if a low dose of 3-AD/11-OXO will cause shut down. I would like to run it with my next cutting cycle(I would like to keep this as non-hormonal/suppressive as possible. So far I have this:
WKS 1-2 JW with Clen
WKS 3-4 JW/BAM IGF-1
WKS 5-6 BAM/Pro Anabol Clen
WKS 7-8 Pro Anabol IGF-1
I will also be running cissus the entire time.
I would like to add in some 3-ad/11-oxo for the fat loss effects but I do not want to cause suppression being I will be doing a epi/havoc cycle once this is done. The IGF-1 is also for a tendon injury, IGF-1 works miracles on injuries..
 
its been said by FnF in her write up she posted it shouldnt be toxic like the common toxic prohormones were. now if its not toxic whatsoever i dont know but im sure its not to a point that one would have to compensate for it with support supps otherwise i dont think she would have even made this point. :thumbsup:

and im no rep of either AX or Ergo so wait for their official answer on the 3-AD but i think it will still be slightly suppressive if taken at a low dose, BUT your going to be taking it with other supps that are supposed to upregulate HTPA production and raise test levels so its neg effect may be negated... this would be a good question for Dr. D
 
... une 1st is the release, its up to retailers when they actually list it and start sales.... i woulda waited for twice the amount of compound per bottle and increased absorbtion.....
 
well keep us updated whatever you guys do as these are new supps and everyone is curious what they actually do. periodic updates are great, detailed logs are even better :thumbsup:
 
WhatsaRoid? said:
This is a pretty good thread, I could jus hold off on all my questions and let you guys ask and figure em out. Anyway I'ma try 3ad and mtst for some summer fun. Hurry and start the log already Zombie!
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;) im just waiting on my elbow to heal thats all i need to start my 3-ad
 
gogo said:
Yeah i hear ya.. " feels like 600mg/week of test"
common
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I thought that was a little crazy too because I make great gains on 400mg/week of testosterone cypionate alone. To make even greater gains with 3-AD seems off the wall. But, I have a feeling 3-AD will prove to be the next best thing anyway...

I already purchased 11oxo to get a jump on things, and will continue with 3-AD once it's available. I'm not all that interested in Pro-Anabol at this time - but I may consider it in the future...
 
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