The New Product Release Thread

thebigt said:
with all the other stuff that has zinc....??? how much zinc can you take before it becomes toxic?
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The National Institutes of Health considers 40 mg of zinc a day to be the upper limit dose for adults and 4 mg of zinc a day for infants under age 6 months

Signs of too much zinc include nausea, vomiting, loss of appetite, stomach cramps, diarrhea, and headaches. When people take too much zinc for a long time, they sometimes have problems such as low copper levels, lower immunity, and low levels of HDL cholesterol (the “good” cholesterol)
 
Rocket3015 said:
The National Institutes of Health considers 40 mg of zinc a day to be the upper limit dose for adults and 4 mg of zinc a day for infants under age 6 months

Signs of too much zinc include nausea, vomiting, loss of appetite, stomach cramps, diarrhea, and headaches. When people take too much zinc for a long time, they sometimes have problems such as low copper levels, lower immunity, and low levels of HDL cholesterol (the “good” cholesterol)
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So basically if you're taking too much zinc you might actually start to think you have corona.
 
Ghost Update

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Ghost BCAA Lemon Lime - 1:20
Strawberry Kiwi - 2:25
CG Contract - 6:30
New Shakers - 10:15 -- Launch Tomorrow 4/9/2020
Apparel of Month - 11:00 -- Launch Tomorrow 4/9/2020
Ghost Greens (Lime & Original) - 13:00 - Launch 4/22/2020
 
I started getting some spring allergies a week or two ago and my wife was convinced I had it......
 
The Solution said:
3 New Merica Energy Flavors Confirmed:

Alpine Pew Pew
Country Fair
Patriot’s Punch

No ETA on when they will be released or info on flavors.
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Pew Pew ?!?!

Who is naming these?*

*Imma still try em
 
New brand with some good looking new products
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Afi140 said:
New brand with some good looking new products
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Would be better if they said what the ingredients were extracted for
 
ironkill said:
Also an error on the label. 10% ara, not 40%. A little misleading
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Yeah, now I may actually be willing to try this as I can’t handle ARA. Since it’s only 10% ARA it shouldn’t really have much of an effect on me.

Elevate and Carved seem more interesting to me personally. Anyone know if there are discount codes on these?
 
Rocket3015 said:
@ELROCK What negative effect does ARA have on you ?
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Horrible on my joints and old nagging injuries. I also get severe DOMS from ARA.

If you can handle ARA I think it works well as a natural anabolic, but I think it’s best utilized by young gym goes that don’t have bad joints or long lasting injuries or surgeries. That’s just in my opinion. I don’t use it because I am over 35 years old and have a history of sports and weightlifting injuries along with multiple surgeries over the years.
 
ELROCK said:
Horrible on my joints and old nagging injuries. I also get severe DOMS from ARA.

If you can handle ARA I think it works well as a natural anabolic, but I think it’s best utilized by young gym goes that don’t have bad joints or long lasting injuries or surgeries. That’s just in my opinion. I don’t use it because I am over 35 years old and have a history of sports and weightlifting injuries along with multiple surgeries over the years.
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I did not realize this, so as a 62 year old with a lot of joint pain it is probably not for me.
 
Label says 266mg per serving (4 capsules) but the nutritional label says 266mg PER capsule... for the 1g+ total.

If the website or label would show what its extracted for, its a great product. Don't have to buy the carnitine salt as its included.

Although, I thought you shouldn't take anti inflammatory products (curcumin) around ARA?
 
tyga tyga said:
Label says 266mg per serving (4 capsules) but the nutritional label says 266mg PER capsule... for the 1g+ total.

If the website or label would show what its extracted for, its a great product. Don't have to buy the carnitine salt as its included.

Although, I thought you shouldn't take anti inflammatory products (curcumin) around ARA?
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I wrote this in another thread, copy and pasted relevant info here for you: (Note, ARA uses enzymes like COX and others to convert into active prostaglandins. PGF2a is the one we want from ARA use, we do not want PGE2 as this is why people get really sore and increased muscle damage.)

Next I theorized that since curcumin blunted post-wo blood levels of some inflammatory markers that it could blunt the adaptive process. Blood levels of any cytokine related to exercise is simply a proxy to what is happening in the muscle. The main cytokine of interest is IL-6 for muscle growth. Curcumin has shown mixed results on blood levels of IL-6 after exercise. More often then not, curcumin really only impacts post-wo blood levels of IL-8. IL-8 in the blood after exercise is rare and only related to the needed generation of an inflammatory response to signal for infiltrating immune cells to enter the damaged tissue, to help with repair, not growth. Curcumin can impact inflammation mainly by inhibiting Nf-kB, it is week at inhibiting COX-1 and COX-2 directly like NSAIDs do. It can also inhibit the production on the prostaglandin PGE2 specifically. This is not all that important, PGE2 is associated with muscle breakdown and the prostaglandin we work after exercise is PGF2a, unlikely to be a factor related to curcumin use. Nf-kB is upsteam of COX-1 and COX-2, it doesn't seem curcumin has a strong effect all the way downstream as there are mixed results on post-wo blood levels of TNF-a and IL-6. Regardless, inhibiting Nf-kB has been implicated in enhancing muscle repair and regeneration processes. In fact, muscles being deficient in Nf-kB has been associated with hypertrophy as well. I doubt curcumin has a strong effect on post-wo inflammatory signals related to adaptations.

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And:

Prostaglandins are associated with inflammatory processes, like cytokines are, they are of interest as their presence is linked with muscle repair and growth. They help signal protein synthesis. Except this is really only a function of PGF2a produced by the COX-1 and COX-2 activity that is increased in muscle tissue during resistance exercise. PGE2 is also produced by the same route, but it actually promotes muscle breakdown. Curcumin is very weak at inhibiting COX-1 and COX-2, it primarily works to regulate Nf-kB. It also inhibits (mPGES)-1 to specifically inhibit PGE2, not PGF2a. Its effects on Nf-kB, COX-1, and COX-2 are in relation to exercise is likely minimal at best since it does not impact protein synthesis or reliably decreases post-wo tumor necrosis factor-alpha (TNF-a) or IL-6 plamsa levels.

I cannot speak for boswellic acids though, they tend to inhibit 5-LOX directly and I am unsure how much influence that will have on PGE2 and PGF2a in the context of resistance exercise pathology.
 
Gaspari Proven Immunity
Arriving Next Week
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1.05g of vitamin C
800IU of vitamin D
27.5mg of zinc
2.5g of oat extract as a source of beta-glucan

Flavor: Refreshing Citrus flavor (Stevia Sweetened)
 
BigGame84 said:
Elevate looks interesting. New company, they have any initial discount codes?
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AB10 is in their bio on insta for 10% off. Haven’t tried it but should be good
 
SweetLou321 said:
I wrote this in another thread, copy and pasted relevant info here for you: (Note, ARA uses enzymes like COX and others to convert into active prostaglandins. PGF2a is the one we want from ARA use, we do not want PGE2 as this is why people get really sore and increased muscle damage.)

Next I theorized that since curcumin blunted post-wo blood levels of some inflammatory markers that it could blunt the adaptive process. Blood levels of any cytokine related to exercise is simply a proxy to what is happening in the muscle. The main cytokine of interest is IL-6 for muscle growth. Curcumin has shown mixed results on blood levels of IL-6 after exercise. More often then not, curcumin really only impacts post-wo blood levels of IL-8. IL-8 in the blood after exercise is rare and only related to the needed generation of an inflammatory response to signal for infiltrating immune cells to enter the damaged tissue, to help with repair, not growth. Curcumin can impact inflammation mainly by inhibiting Nf-kB, it is week at inhibiting COX-1 and COX-2 directly like NSAIDs do. It can also inhibit the production on the prostaglandin PGE2 specifically. This is not all that important, PGE2 is associated with muscle breakdown and the prostaglandin we work after exercise is PGF2a, unlikely to be a factor related to curcumin use. Nf-kB is upsteam of COX-1 and COX-2, it doesn't seem curcumin has a strong effect all the way downstream as there are mixed results on post-wo blood levels of TNF-a and IL-6. Regardless, inhibiting Nf-kB has been implicated in enhancing muscle repair and regeneration processes. In fact, muscles being deficient in Nf-kB has been associated with hypertrophy as well. I doubt curcumin has a strong effect on post-wo inflammatory signals related to adaptations.

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And:

Prostaglandins are associated with inflammatory processes, like cytokines are, they are of interest as their presence is linked with muscle repair and growth. They help signal protein synthesis. Except this is really only a function of PGF2a produced by the COX-1 and COX-2 activity that is increased in muscle tissue during resistance exercise. PGE2 is also produced by the same route, but it actually promotes muscle breakdown. Curcumin is very weak at inhibiting COX-1 and COX-2, it primarily works to regulate Nf-kB. It also inhibits (mPGES)-1 to specifically inhibit PGE2, not PGF2a. Its effects on Nf-kB, COX-1, and COX-2 are in relation to exercise is likely minimal at best since it does not impact protein synthesis or reliably decreases post-wo tumor necrosis factor-alpha (TNF-a) or IL-6 plamsa levels.

I cannot speak for boswellic acids though, they tend to inhibit 5-LOX directly and I am unsure how much influence that will have on PGE2 and PGF2a in the context of resistance exercise pathology.
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I appreciate the breakdown and reasoning why we put that in there
 
tyga tyga said:
Label says 266mg per serving (4 capsules) but the nutritional label says 266mg PER capsule... for the 1g+ total.

If the website or label would show what its extracted for, its a great product. Don't have to buy the carnitine salt as its included.

Although, I thought you shouldn't take anti inflammatory products (curcumin) around ARA?
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It’s 1067 per four capsules which is a serving. 266 per cap

Thanks for the compliment
 
ELROCK said:
Horrible on my joints and old nagging injuries. I also get severe DOMS from ARA.

If you can handle ARA I think it works well as a natural anabolic, but I think it’s best utilized by young gym goes that don’t have bad joints or long lasting injuries or surgeries. That’s just in my opinion. I don’t use it because I am over 35 years old and have a history of sports and weightlifting injuries along with multiple surgeries over the years.
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I’m 37 and had joint pains too. Give it a try it hits different trust me.

Elevate will be perfect for you and people with joint issues and people with past injuries
 
abformulations said:
I’m 37 and had joint pains too. Give it a try it hits different trust me.

Elevate will be perfect for you and people with joint issues and people with past injuries
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ha, i'm 61 and avoid it like the plague...last time I tried it took a week to get back to my 'normal' aches and pains!!!

it does work though, great supplement for those who can tolerate it.
 
abformulations said:
I appreciate the breakdown and reasoning why we put that in there
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SweetLou321 said:
I wrote this in another thread, copy and pasted relevant info here for you: (Note, ARA uses enzymes like COX and others to convert into active prostaglandins. PGF2a is the one we want from ARA use, we do not want PGE2 as this is why people get really sore and increased muscle damage.)

Next I theorized that since curcumin blunted post-wo blood levels of some inflammatory markers that it could blunt the adaptive process. Blood levels of any cytokine related to exercise is simply a proxy to what is happening in the muscle. The main cytokine of interest is IL-6 for muscle growth. Curcumin has shown mixed results on blood levels of IL-6 after exercise. More often then not, curcumin really only impacts post-wo blood levels of IL-8. IL-8 in the blood after exercise is rare and only related to the needed generation of an inflammatory response to signal for infiltrating immune cells to enter the damaged tissue, to help with repair, not growth. Curcumin can impact inflammation mainly by inhibiting Nf-kB, it is week at inhibiting COX-1 and COX-2 directly like NSAIDs do. It can also inhibit the production on the prostaglandin PGE2 specifically. This is not all that important, PGE2 is associated with muscle breakdown and the prostaglandin we work after exercise is PGF2a, unlikely to be a factor related to curcumin use. Nf-kB is upsteam of COX-1 and COX-2, it doesn't seem curcumin has a strong effect all the way downstream as there are mixed results on post-wo blood levels of TNF-a and IL-6. Regardless, inhibiting Nf-kB has been implicated in enhancing muscle repair and regeneration processes. In fact, muscles being deficient in Nf-kB has been associated with hypertrophy as well. I doubt curcumin has a strong effect on post-wo inflammatory signals related to adaptations.

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And:

Prostaglandins are associated with inflammatory processes, like cytokines are, they are of interest as their presence is linked with muscle repair and growth. They help signal protein synthesis. Except this is really only a function of PGF2a produced by the COX-1 and COX-2 activity that is increased in muscle tissue during resistance exercise. PGE2 is also produced by the same route, but it actually promotes muscle breakdown. Curcumin is very weak at inhibiting COX-1 and COX-2, it primarily works to regulate Nf-kB. It also inhibits (mPGES)-1 to specifically inhibit PGE2, not PGF2a. Its effects on Nf-kB, COX-1, and COX-2 are in relation to exercise is likely minimal at best since it does not impact protein synthesis or reliably decreases post-wo tumor necrosis factor-alpha (TNF-a) or IL-6 plamsa levels.

I cannot speak for boswellic acids though, they tend to inhibit 5-LOX directly and I am unsure how much influence that will have on PGE2 and PGF2a in the context of resistance exercise pathology.
Click to expand...

I will further add that although 5-LOX does not appear to interact with PGF2a production, it is important for the production of specialized pro-resolving mediators (SPMs) production. Other compounds shown to inhibit COX and LOX enzymes with a high degree of specificity and potency have been shown to delay or reduce the production of SPMs. This is important for the resolution of inflammation and completion of tissue repair, it may even be important for adaptations to resistance exercise. Blocking the production of SPMs does open one up to the a potential issue of chronic low-grade inflammation. This is one potential draw back of adding boswellic acids to a supplement such as this. ARA conversion into other pro-inflammatory mediators (via COX, LOX, CYP, ect) is partially responsible for this phase switch to SPMs production so we could be losing out on some benefits of this ingredient when combined with boswellic acids. It is possible that PGF2a is only one part of what makes ARA effective, it could be the large influx of general pro-inflammatory mediators leading to a higher influx of SPMs could also be a factor in results. This is an extrapolation of course as time will tell more as there is always a constant struggle between inflammatory mediators, muscle damage, repair, hypertrophy, and inflammation resolution impacting which adaptations we get and how much.

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Just to quickly summarize the ArA discussion so everyone is on the same page and understands the difference between softgels and capsules.

Softgels allow for ArA oil. Take X-Gels for example, as that is what I am familiar with. Each softgel is 625mg ArA oil blend at a 40% standardization, yielding 250mg ArA per softgel. 4 caps gets you 1g ArA.

If a product is encapsulated, it’s a powder, and is at a 10% standardization.
 
aaronuconn said:
But it’s really 26mg of ArA per cap right?

1067mg (10% standardization) for a 4 cap serving. So it yields 106.7mg of ArA per 4 caps, or ~26.6 per cap.
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Math looks good .. also dont just think of age and disarm ARA .. i know plenty of kids who cant handle this at 20-24yrs .. and then know 30-50yrs old who love it

Yes inflmmation have to happen inorder for it to work .. if you want to get rid of all of ARA you would have to be a Vegan
 
GQdaLEGEND said:
Math looks good .. also dont just think of age and disarm ARA .. i know plenty of kids who cant handle this at 20-24yrs .. and then know 30-50yrs old who love it

Yes inflmmation have to happen inorder for it to work .. if you want to get rid of all of ARA you would have to be a Vegan
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Well said. ARA destroyed me when I was around only 22 years old as I recall. Like, crippling effects on joints and recovery. At 29 now, with 7 more years of strength training under my belt... I would probably just die
 
GQdaLEGEND said:
Math looks good .. also dont just think of age and disarm ARA .. i know plenty of kids who cant handle this at 20-24yrs .. and then know 30-50yrs old who love it

Yes inflmmation have to happen inorder for it to work .. if you want to get rid of all of ARA you would have to be a Vegan
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Was this in response to something I said lol? Or just a general statement? I’m aware of everything you said.
 
GQdaLEGEND said:
Math looks good .. also dont just think of age and disarm ARA .. i know plenty of kids who cant handle this at 20-24yrs .. and then know 30-50yrs old who love it

Yes inflmmation have to happen inorder for it to work .. if you want to get rid of all of ARA you would have to be a Vegan
Click to expand...

Was this in response to something I said lol? Or just a general statement? I’m aware of everything you said.
 
Hyde said:
Well said. ARA destroyed me when I was around only 22 years old as I recall. Like, crippling effects on joints and recovery. At 29 now, with 7 more years of strength training under my belt... I would probably just die
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I first used ArA when I was 22 or 23 with no issues. Just ran 2 bottles of it recently at 28 and my knees were achy lol. Great results, but first time noticing joint pain.
 
Hyde said:
Well said. ARA destroyed me when I was around only 22 years old as I recall. Like, crippling effects on joints and recovery. At 29 now, with 7 more years of strength training under my belt... I would probably just die
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I first used ArA when I was 22 or 23 with no issues. Just ran 2 bottles of it recently at 28 and my knees were achy lol. Great results, but first time noticing joint pain.
 
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