Looks like we should be all bottled up by Wednesday. I'll have some overnighted to cover orders, so you can get started ASAP, and before Christmas.
Presale will be ending tonight.
Presale will be ending tonight.
Product page hasn't been updated yet. Correct, no capsaicin.The new version doesn’t have capsaicin correct? Capsaicin isn’t listed on the label but is in the ingredients list on the product page.
I was able to make a pretty incredible Capsaicin solution, and I've taken 50mg and had zero side effects....but that's in a water solution.In for 6 bottles. The previous version was great, but the capsaicin was rough on my stomach. Looking forward to giving the new version a whirl this spring
Excellent. Now on to MyoSnergy please!DCP is done. We are 2 for 2 with this new production company and I am thrilled! Now we wait for it to get here, plenty of time to get your order in before Christmas/New Year.
Epitome will be ready to go first.Excellent. Now on to MyoSnergy please!
Whats the difference in the new Epitome? I have two bottles of the old and was wondering if I should upgrade. | ||||
In which case you might want to ask dsade about his supersaturated liquid capsaicin concoction.Another question. How important was the capsaicin? Any negatives with taking it out? Added anything in its place? Well thats 3 questions lol. I have gerd but for some reason can tolerate the capsaicin in DCP quite well. Just wondering if I should add some to my stack if capsaicin has a lot of benefit. I need every metabolism boost I can get!!!
You should see my latest monstrosity. I'm terrified to even try it. I got about 3 grams into 75ml, using a hydroxypropyl-cyclodextrin in an alcohol and CARBONATED water carrier, closed up in a sealed container for 2 weeks.Matt has been working on some capsaicin concoctions that are incredible. I haven't tried the liquid stuff, but he had a compound that allowed me to take up to 200 mg of capsaicin with no discomfort. I think it was just too complicated and unreliable to produce.
DCP was brutal on me sometimes with the capsaicin...and I tolerate it fairly well. He had a strong dose in there.
There will be a little less thermogenic effect, but at the same time I've made two improvements. The new Hibiscus Extract is an extemely potent PPAR-delta agonist. As well, DCP is gonna be the first to get the Mucoadhesive treatment.Another question. How important was the capsaicin? Any negatives with taking it out? Added anything in its place? Well thats 3 questions lol. I have gerd but for some reason can tolerate the capsaicin in DCP quite well. Just wondering if I should add some to my stack if capsaicin has a lot of benefit. I need every metabolism boost I can get!!!
One of the main ingredients in Epitome is the Birch Bark - more specifically Betulinic Acid. Oral absorption is HORRIBLE for many reasons - main one being that it resists being passively absorbed and transits VERY rapidly through the gut. It also has incredibly crappy solubility.Can you discuss the Epitome upgrade or not until near release? You explained you cant feel Epitome but I really love it. I do calorie restriction/low carb during the weekdays 800 to 1200 and maintenance/slightly above during weekend. It keeps the weight coming off. Before Epitome it was a lot slower.
Noted I also use DCP and Brite but started with Epitome. I'm 39 and lost 43 pounds this year. Took some time off from diet multiple times because of injury and gained a little back. If anyone hasnt tried it I recommend it for ongoing fat loss.
Like I said I only consume 800 to 1200 during weekdays and no slow down in weight loss while using Epitome.
Back to orginally question. Care to discuss Epitome upgrade or gotta wait unfortunately. Great products
I want to pre reserve some presales bottles of the small batch lol. Will bribeOne of the main ingredients in Epitome is the Birch Bark - more specifically Betulinic Acid. Oral absorption is HORRIBLE for many reasons - main one being that it resists being passively absorbed and transits VERY rapidly through the gut. It also has incredibly crappy solubility.
I was able to perfect the process for making a cocrystal with Vitamin C which improves solubility, and therefore absorption, 27-fold.
ALso see the above post re: Mucoadhesive. Using Chitosan again for this purpose, which will also help absorption of the Orthsiphon alcohol extract.
I'm also swapping out the Queen Bee Acid for Gypenosides, which in addition to still potently activating AMPK, has other (blood sugar, BRITE fat conversion) beneficial properties.
Finally, I am adding in Stem Bromelain - which is a potent PDE-3b inhibitor (something I've been itching to tackle since 2005). PDE-3b is a phosphodiesterase enzyme activated by Insulin (among other things) that is responsible for crippling Lipolysis during periods of elevated insulin (post meal, etc.). The combination of the Gypenosides and Bromelain will increase fat burning rate dramatically, most especially in the context of what Epitome is designed for - specifically, those more in the overweight category.
From PDE3B to the regulation of energy homeostasis
The incidence of obesity in the developed world is increasing at an alarming rate. Concurrent with the increase in the incidence of obesity is an increase in the incidence of type 2 diabetes. Cyclic AMP (cAMP) and cGMP are key second messengers in all ...www.ncbi.nlm.nih.gov
The Role of PDE3B Phosphorylation in the Inhibition of Lipolysis by Insulin - PubMed
Inhibition of adipocyte lipolysis by insulin is important for whole-body energy homeostasis; its disruption has been implicated as contributing to the development of insulin resistance and type 2 diabetes mellitus. The main target of the antilipolytic action of insulin is believed to be...www.ncbi.nlm.nih.gov
Anyway, for this first batch I only have the resources to "spike" the birch bark extract with the BA/AA cocrystals. Future batches will be using pure cocrystals as we are able to scale up. I'm SO extremely excited for this upgrade, and will be able to keep the price close to the same.
Wow can't wait. Well I can cause I have old version but sounds like I need this.One of the main ingredients in Epitome is the Birch Bark - more specifically Betulinic Acid. Oral absorption is HORRIBLE for many reasons - main one being that it resists being passively absorbed and transits VERY rapidly through the gut. It also has incredibly crappy solubility.
I was able to perfect the process for making a cocrystal with Vitamin C which improves solubility, and therefore absorption, 27-fold.
ALso see the above post re: Mucoadhesive. Using Chitosan again for this purpose, which will also help absorption of the Orthsiphon alcohol extract.
I'm also swapping out the Queen Bee Acid for Gypenosides, which in addition to still potently activating AMPK, has other (blood sugar, BRITE fat conversion) beneficial properties.
Finally, I am adding in Stem Bromelain - which is a potent PDE-3b inhibitor (something I've been itching to tackle since 2005). PDE-3b is a phosphodiesterase enzyme activated by Insulin (among other things) that is responsible for crippling Lipolysis during periods of elevated insulin (post meal, etc.). The combination of the Gypenosides and Bromelain will increase fat burning rate dramatically, most especially in the context of what Epitome is designed for - specifically, those more in the overweight category.
From PDE3B to the regulation of energy homeostasis
The incidence of obesity in the developed world is increasing at an alarming rate. Concurrent with the increase in the incidence of obesity is an increase in the incidence of type 2 diabetes. Cyclic AMP (cAMP) and cGMP are key second messengers in all ...www.ncbi.nlm.nih.gov
The Role of PDE3B Phosphorylation in the Inhibition of Lipolysis by Insulin - PubMed
Inhibition of adipocyte lipolysis by insulin is important for whole-body energy homeostasis; its disruption has been implicated as contributing to the development of insulin resistance and type 2 diabetes mellitus. The main target of the antilipolytic action of insulin is believed to be...www.ncbi.nlm.nih.gov
Anyway, for this first batch I only have the resources to "spike" the birch bark extract with the BA/AA cocrystals. Future batches will be using pure cocrystals as we are able to scale up. I'm SO extremely excited for this upgrade, and will be able to keep the price close to the same.
Giiiiive ussss the Skyn Fyrm!!!!For those following my Skyn Fyrm updates, this will interest you. IF you have loose skin from pregnancy or massive fat loss, then this will interest you.
If none of this interests you....then why are you reading it? Go play Xbox.
PPARβ/δ: Linking Metabolism to Regeneration
In contrast to the general belief that regeneration is a rare event, mainly occurring in simple organisms, the ability of regeneration is widely distributed in the animal kingdom. Yet, the efficiency and extent of regeneration varies greatly. Humans can ...www.ncbi.nlm.nih.gov
I 2nd thisGiiiiive ussss the Skyn Fyrm!!!!
Depasi10Ahhh shoot I missed the pre sale... any coupon codes available?
Could this mucoadhesive effect affect other things we’re taking?There will be a little less thermogenic effect, but at the same time I've made two improvements. The new Hibiscus Extract is an extemely potent PPAR-delta agonist. As well, DCP is gonna be the first to get the Mucoadhesive treatment.
Mucoadhesive - A mucoadhesive is something which, when it hits the bile-rich environment (as opposed to highly acidic) of the small intestine, forms a sticky matrix. This matrix not only encases ALL of the less water soluble ingredients (most of the ingredients from DCP are either ethanol or dichloromethane extracts, which SUCK at absorbing), but sticks to the walls of the intestines while it slowly transits through the GI Tract. The result is that our active ingredients are in contact with the intestinal cells for a ,much longer period, and absorption is enhanced markedly.
Chitosan. Chitosan is a de-acetylated form of Chitin, which is a protein that comprises things like shrimp shells*. When it's deacetylated to Chitosan, it forms a very nice free flowing powder. When it hits the acetic acid, secreted by gut bacteria, it is reacetylated into Chitin, which is a BEAUTIFUL mucoadhesive with bioactive properties of its own.
The end result is a ,much more potent formula in terms of PPAR activation - meaning enhanced liver fatty acid oxidation (From PPAR Alpha activation) and a much more enhanced PPAR-delta activation (enhanced fatty acid oxidation in muscle, heart, etc) as well as a noticeable boost in endurance.
*there is zero evidence that Chitin/Chitosan are allergens. We have put a Shellfish allergy warning on the label for liability, but I was unable to find any case studies on allergic reactions to Chitosan. As always, consult your physician.
Or would it effect things only taken at the same time if so?Could this mucoadhesive effect affect other things we’re taking?
Only if you take it at the same time, and even then probably not much. I experimented around to find the perfect amount of Chitosan to be able to enhance the absorption of the rest of the formula, but the "matrix" will travel through the gut as kind of a unit.Or would it effect things only taken at the same time if so?
Excellent. Thanks man.Only if you take it at the same time, and even then probably not much. I experimented around to find the perfect amount of Chitosan to be able to enhance the absorption of the rest of the formula, but the "matrix" will travel through the gut as kind of a unit.
THe surface area of the gut is enough to accomodate DCP and other supplements/meds.
You know, I got 6 bottles the other day. They came late afternoon so I took 4 pills as my first dose around dinner time. I wound up having to go do some stuff and spent about 2 hours before I could eat and I was getting hangry. I didn't confirm either, but at the time I really felt my blood sugar had tanked pretty hard. I find this hard to believe because no other product I have tried, including large doses of berberine and even metformin itself, has even come close to making my blood sugar tank.Has anyone else tried the new DCP update yet? I’m keto, but I think it’s taking my blood sugar really low; haven’t verified with blood monitor yet but I will when I can. Also making me hungry oddly enough.
Matt puts his heart and soul into this stuff. He is a good person and good friend and he is definately doing this out of passion and is an anomaly in the industry.I never really looked much into Evomuse before, but I like this guy (the owner) a lot. He is my kind of formulator. Most company owners have little to nothing to do with the formulation of their products...and if they do, they just copy what everyone else is doing. You have to really love what you do (rather than just care about money) to put his kind of time and thought into making something unique and effective. He has my respect.
Matt is an "OG" he was formulating formulas before formulating was coolI never really looked much into Evomuse before, but I like this guy (the owner) a lot. He is my kind of formulator. Most company owners have little to nothing to do with the formulation of their products...and if they do, they just copy what everyone else is doing. You have to really love what you do (rather than just care about money) to put his kind of time and thought into making something unique and effective. He has my respect.
Got 1 message from a new user who's down 12 pounds in about 14 days, but against advice she's doing a starvation diet too.whats everyone's initial thoughts on this so far? Haven't started my bottles just yet.
Zoe Labs? I think you might be confused. DCP has been my exclusive design/property since 2006.Is there an article someone can point me to for a crash course on DCP? I know zoe labs made it and its supposed to be good stuff, but i had no idea what it does.
Here is the write up to the previous version:Is there an article someone can point me to for a crash course on DCP? I know zoe labs made it and its supposed to be good stuff, but i had no idea what it does.
the shipment was updated today… it seems like its on its way.@dsade, got my shipping notification, can you please put on hold? and ship when its possible with bmp stuff?
order number is #7498
Any updates on Skyn Fyrm @dsade ?For those following my Skyn Fyrm updates, this will interest you. IF you have loose skin from pregnancy or massive fat loss, then this will interest you.
If none of this interests you....then why are you reading it? Go play Xbox.
PPARβ/δ: Linking Metabolism to Regeneration
In contrast to the general belief that regeneration is a rare event, mainly occurring in simple organisms, the ability of regeneration is widely distributed in the animal kingdom. Yet, the efficiency and extent of regeneration varies greatly. Humans can ...www.ncbi.nlm.nih.gov
I’d love to know the same. Especially if the ingredients have any synergy.Anyone taking DCP and Brite stacked? Taking them at the same time? Apart? Super curious as to how/when everyone is doing this.
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