Sceletium is a good but often subtle nootropic that I, and others, find actually goes well with other more "stimulating" or "energizing" nootropics/stims. It is good for reducing stress/anxiety and improving mood, but I would NOT expect actual "euphoria" from it. I've been using it daily in NootropiMax for a long time now, as well as using various bulk sources prior to NootropiMax's release (which means that NootropiMax contains seletium, of course). If you just want bulk sceletium to try as opposed to just bulk powder, but prefer an extract that is essentially identical to Zembrin for a fraction of the price of Zembrin, PM me.
It's actually this extract, which is made by Afrigetics (which confuses me a little bit, as their bottle says it's a registered trademark of Afrigetics, which it is, but their writeup on their website says that they, OL, trademarked it).
I’m fully aware of the cognitive and mood benefits of sceletium, I was asking if there was any actual research showing increased endurance, which it seems there is not. And don’t go thinking I’m knocking the ingredient; I’ve used it for years and included it in NootropiMax as well. I was genuinely curious if there was some new research I haven’t seen showing increased endurance. Either way, it’s worth using just for its mood benefits anyway IMO.
I know I’m probably beating a dead horse at this point, but I figured since you’re the one making the claims, you’d be able to provide at least one study to support your claims instead of telling me to look it up.
No need to get hostle.
I’m not being hostile, I’m stating the universal fact/rule in scientific literature that the burden of proof rests with the person making the claim; if you’re making the claim, you should also provide the evidence, not simply tell other people to look it up. I’d assume you agree with this, or why even have a write-up in the first place? I read through your write-up and it didn’t provide any answers, which is why I asked here. That’s hostile? Also, there are a few significant assumptions here. We know that sceletium is an effective PDE4 (not PED4, I assume that’s just your autocorrect though) inhibitor, but can we inherently conclude that this PDE 4 inhibition will increase cAMP to such a degree that it will in turn increase endurance via the other MoAs proposed? I’d say the best we can say is that sceletium may increase endurance, and that we have a proposed MoA for it, but to state that it DOES increase endurance without so much as a rodent study on the topic, or even a study measuring increases in cAMP (we need to know the magnitude of the effects, not just the effect itself) in humans, is disingenuous.
