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The Official "Stablon is a smart drug" thread

Hyperfluxe said:
Has anyone noticed an ill effect on their training from tianeptine? I've been using 50mg of tianeptine sulfate once daily in the morning with an empty stomach. It's been 17 days now, and although it has noticeable mood brightening, antidepressant and anxiolitic effects, it seems to tank my recovery and ability to handle volume. Maybe it's just the training stress though.

Apart from the positive effects noted above, the negative effects so far are constant lethargy, reduced libido and appetite, and constipation.

The analgesic effects were very notable during the first week, I felt great in the gym but I suspect that is an easy way to hurt yourself. It went away after the first week.

At this point, I don't think I want to take it chronically but I would like to acquire its long-term benefits of normalizing your HPA axis, promoting BDNF, repairing neuronal damage due to stress and increasing synaptic plasticity. Does anyone know how long I need to keep taking it for? The original Server literature states that the sodium salt needs 6-8 weeks to work well, so I'd bet it's even longer for the sulfate salt but I'm not sure I want to be lethargic for that long.
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Have you tried splitting the dose and taking 25 mg in the morning and afternoon? For me, tianeptine sulfate has increased my energy (much better workouts), libido and appetite...basically the opposite of what you experience. However, if I take 50 mg at once then it's much more calming. Currently I'm taking 25 mg in the morning and afternoon along with 300 mg of ksm-66 ashwagandha. The ashwagandha seems to help a lot at reducing the overstimulation I experience with tianeptine sulfate alone.

edit: forgot to add that I also experience constipation with tianeptine. Taking 400-600 mg of magnesium throughout the day has helped with that.
 
Trying that today. That's interesting how a single 25mg dose can be stimulating while a double dose is sedating. Reminds me of curcumin.
 
jswain34 said:
No bud. He was taking "300 12.5mg caps as a single dose with MULTIPLE DOSES daily". As in 1 dose would be 3.75g and he was doing this multiple times a day. Seemed crazy to me, but who the ef knows lol.
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I can verify the guy must've definitely been trolling or something, taking very large doses causes EXTREME nausea. I've experimented with some big doses recently in the hopes for increased productivity, larger than I've tried in the past. Definitely not a good feeling. And so I'd say addiction to this stuff shouldn't be a problem between the heavy nausea and receptor-downregulation.
 
A single 25mg sulfate dose in the AM was great. It maintained all the positive benefits but no fatigue this time. I took another 25mg cap at lunch, it made me slightly sedated. I think I'll stick to 25 once in the morning.

Since ashwaganda was mentioned in this topic... There is a night and day difference better Sensoril and KSM-66 for me. 600mg KSM for months did absolutely nothing subjectively, but when I take a single 125mg dose of Sensoril it feels like a low dose benzo. Sleep quality increases as per sleep cycle on my phone.
 
So I'm still feeling lethargy, brain fog and fatigue from a single 25mg sulfate dose. It's been 23 days, I think I'll stop. It looks like quite a few people have this issue on Reddit and Longecity, the sulfate salt being more prevalent than the sodium. I just don't do well with anxiolitics, they just make me sleepy and sap my drive. Looks like Semax is what I need.

Also I swear that tianeptine hurts my training. Joints have never felt worse and I have not increased training load.
 
Hyperfluxe said:
So I'm still feeling lethargy, brain fog and fatigue from a single 25mg sulfate dose. It's been 23 days, I think I'll stop. It looks like quite a few people have this issue on Reddit and Longecity, the sulfate salt being more prevalent than the sodium. I just don't do well with anxiolitics, they just make me sleepy and sap my drive. Looks like Semax is what I need.

Also I swear that tianeptine hurts my training. Joints have never felt worse and I have not increased training load.
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Which brand sulfate are you using?
 
GreenMachineX said:
Which brand sulfate are you using?
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Nootropics depot capsules. MisterYouAreSoDumb told me that a few customers reported my issues, they're just not as vocal about it as the ones who've had a positive experience. I am going to give the rest of my caps to a highly anxious friend, I'll report back if anyone's curious.
 
Gutterpump said:
I can verify the guy must've definitely been trolling or something, taking very large doses causes EXTREME nausea. I've experimented with some big doses recently in the hopes for increased productivity, larger than I've tried in the past. Definitely not a good feeling. And so I'd say addiction to this stuff shouldn't be a problem between the heavy nausea and receptor-downregulation.
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Invalid Link Removed

12.5mg x 300 caps tid

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7-800mg a day (a lot less than the above guy, but still a lot). Then after coming off Zoloft, 500mg 7-8x a day. Then 420mg every 2-3 hours later on.

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"I started taking Tianeptine in March, in powder form. I would mix it with water and drink it. I started off with taking about 250 mg per day and got up to about a gram a day by May as the desired effects became harder to achieve. In early June I ran out of Tianeptine and was unable to quickly obtain more. I did a cold turkey withdrawal from it and almost had to check myself into the hospital. I actually had someone drive me to the 24/7 med center but left before a doctor saw me because the office was very crowded and I was unable to sit and felt extremely uncomfortable."



So, it seems like these people went way above and beyond anything close to what is being recommended ITT. I suppose that as long as one realizes it's potential for addiction (especially if you have a history of addiction to antidepressants, opiates, other street drugs, or alcohol) then you should be able to stop yourself and taper down before ever reaching this point. I just wanted to show you and anyone who reads this that there seems to be a very real possibility of addiction and subsequent abuse with Tianeptine.
 
jarrellt67 said:
Well, I'm an idiot. My thinking was way off. This link gives a good description comparing the sodium and sulfate forms - Invalid Link Removed. I don't know if it's completely correct but has good numbers and reasoning to back it up.
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I'm not so sure about his molar estimates, I'm getting that the "sulfate" is only about 91.477% equivalent to the sodium by my calculations. That would make a standard 12.5mg amount of the sodium form equal to ~13.7mg of the "sulfate" (which is likely the hemisulfate dihydrate, but who knows with RCs.) It could easily be tested if a reference std were available.

He and the other commenters at the link you provided do suggest some practical considerations about possible pharmacokinetic differences though, and that's probably the more practical issue for those interested in this compound.
 
Gutterpump said:
Do any of you see an issue with taking a dose of Lithium Orotate at night, while taking tianeptine during the day?
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Did you end up trying lithium with tianeptine? I ordered some lithium orotate to see if it helps reduce the overstimulation/irritability from tianeptine sulfate (ashwagandha worked for that but after a few days ended up making me too tired if taken during the daytime).
 
jarrellt67 said:
Did you end up trying lithium with tianeptine? I ordered some lithium orotate to see if it helps reduce the overstimulation/irritability from tianeptine sulfate (ashwagandha worked for that but after a few days ended up making me too tired if taken during the daytime).
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I've had great success with lemon balm recently. Maybe a dose of that with your tianeptine doses?
 
GreenMachineX said:
I've had great success with lemon balm recently. Maybe a dose of that with your tianeptine doses?
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I'm actually trying to grow some Melissa from a cutting. The lady who gave it to me said be careful because it's quite invasive, but it spreads slow so it seems quite manageable. Just the smell relaxes me. :)

Jarrellt67,
I'd be careful with lithium. The orotate works well for many indeed, but the inevitable tendency toward diminished thyroid output precludes long-term application IMO.
 
The Official "Stablon is a smart drug" thread

jarrellt67 said:
Did you end up trying lithium with tianeptine? I ordered some lithium orotate to see if it helps reduce the overstimulation/irritability from tianeptine sulfate (ashwagandha worked for that but after a few days ended up making me too tired if taken during the daytime).
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I've used lithium orotate a few times here n there (in evenings) while using Tianeptine during the day, and had no problems.

I'm a bit nervous to try it on a daily basis though. I might give it a shot soon with about 150mg of Tianeptine daily. I've been using about 2-300mg of Tianeptine sodium daily for the past couple weeks.
 
Gutterpump said:
I've used lithium orotate a few times here n there (in evenings) while using Tianeptine during the day, and had no problems.

I'm a bit nervous to try it on a daily basis though. I might give it a shot soon with about 150mg of Tianeptine daily. I've been using about 2-300mg of Tianeptine sodium daily for the past couple weeks.
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Are you still taking tianeptine three times a day? Any noticeable comedown if you miss a dose? That's one thing I like about the sulfate version...no major drop in effects later in the day (just a little less energy).

Yeah, lithium orotate has been both good and bad for me in the past. On it's own I find it to be very calming (not sedating) but it also seemed to flatten my mood (no highs or lows). I'm hoping the tianeptine will overcome the mood flattening of lithium while the lithium will overcome the overstimulation of tianeptine. Who knows...worth a shot. I see lithium recommended often to help those that have strong reactions (anger, mood swings, etc) to other antidepressants...so I figured why not try it with tianeptine. Besides, I'd only be taking 5 mg/day so I wouldn't think that would have any longterm negative consequences since the dose is significantly lower than prescription lithium.
 
jarrellt67 said:
Are you still taking tianeptine three times a day? Any noticeable comedown if you miss a dose? That's one thing I like about the sulfate version...no major drop in effects later in the day (just a little less energy).

Yeah, lithium orotate has been both good and bad for me in the past. On it's own I find it to be very calming (not sedating) but it also seemed to flatten my mood (no highs or lows). I'm hoping the tianeptine will overcome the mood flattening of lithium while the lithium will overcome the overstimulation of tianeptine. Who knows...worth a shot. I see lithium recommended often to help those that have strong reactions (anger, mood swings, etc) to other antidepressants...so I figured why not try it with tianeptine. Besides, I'd only be taking 5 mg/day so I wouldn't think that would have any longterm negative consequences since the dose is significantly lower than prescription lithium.
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To be honest, I've been using Tianeptine as a crutch because work has been crazy the past two weeks. I'm using 100mg 3-4 times a day in a non-therapeutic way. Been using it to function. It's bad, I know, but I plan on taking a week's break then running it properly, mixed and measured properly with a solvent. Tolerance builds up quick with this stuff.
 
Gutterpump said:
To be honest, I've been using Tianeptine as a crutch because work has been crazy the past two weeks. I'm using 100mg 3-4 times a day in a non-therapeutic way. Been using it to function. It's bad, I know, but I plan on taking a week's break then running it properly, mixed and measured properly with a solvent. Tolerance builds up quick with this stuff.
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Can understand needing to use something as a crunch when things get bad at work. I use low doses of phenibut during those times (used it daily for months when things were at their worst). At least you're strong, and disciplined, enough to taper the dose back down when things improve. Based on reviews online, not many are when they get to taking doses that high (not sure I would be...which is why I haven't tried).
 
I ended up getting some and love it. Great for focus and overall since of well being. My question is regarding it for drug test? Does it show as a TCA?
My test are sent to the lab (government). I know it's legal so shouldn't be an issue but I'm still weighing the pro and cons of taking it.
 
So far, stacking tianeptine sulfate with lithium orotate is going very well. I'm currently taking 25 mg of tianeptine with 2.5 mg of lithium (1/2 tablet), twice each day. I did try one day to take 5 mg of lithium at the same time as the tianeptine but it was too sedating. The lower dose seems to be taking the edge off the tianeptine and also seems to boost the mood benefits a bit. Hopefully this keeps up.
 
Chiefsnation23 said:
I ended up getting some and love it. Great for focus and overall since of well being. My question is regarding it for drug test? Does it show as a TCA?
My test are sent to the lab (government). I know it's legal so shouldn't be an issue but I'm still weighing the pro and cons of taking it.
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I'm not sure, but I don't believe it would show as a false positive. Let us know what you find out.
 
jarrellt67 said:
Can understand needing to use something as a crunch when things get bad at work. I use low doses of phenibut during those times (used it daily for months when things were at their worst). At least you're strong, and disciplined, enough to taper the dose back down when things improve. Based on reviews online, not many are when they get to taking doses that high (not sure I would be...which is why I haven't tried).
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Starting to ramp my dose down as of last weekend. Only taking 1 x 200mg dose each day, instead of 3x daily. Will likely give it a break before starting it at the recommended dosing protocols. It is hardly working anymore for me, but helped me in time of need.
 
I've heard of deprenyl showing up as a false positive (amphetamine), but not tianeptine. What are you worried it will show up as? An amphetamine or opiate? I'm not sure what TCA stands for.
 
The Official "Stablon is a smart drug" thread

Just an update, I managed to ween off of super high doses of Tianeptine in less than a week. No withdrawals. Went from 800mg (roughly) to 0.
 
Chiefsnation23 said:
Nice dude. Congrats. How long were you dosing prior to weening off?
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I was using Tianeptine again for about a month. I went through a whole 10g container but I was dealing with insane stress at home and work. It definitely helped but I'll never high dose just for energy/productivity anymore.

I've been going through a breakup with a girl I live with, it's been intense, and pretty horrible at home. I hadn't been sleeping and my workload at the office has been crazy, which is why I started using Tianeptine like this.
 
Gutterpump said:
I need to look into other nootropics for anxiety, stress, focus and energy
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What have you tried so far? I never delved into anything like Tianeptine for stress, but I did find that KSM-66 and Kava helped with stress/anxiety when I was going through a rough-patch and break-up a month ago.
 
muscleupcrohn said:
What have you tried so far? I never delved into anything like Tianeptine for stress, but I did find that KSM-66 and Kava helped with stress/anxiety when I was going through a rough-patch and break-up a month ago.
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I've used neurobalance (special form of phenibut) but that's about all for stress / sleep.

I've tried all sorts of forms of choline with piracitam, never did much for me for focus, etc. I've used deprenyl as well, was ok.

Ativan was amazing for stress / short term anxiety but it's a drug too.
 
jarrellt67 said:
I'm going to initially try it without choline. For some reason, I never reacted well to cdp-choline or alpha gpc (made me very depressed). I eat a lot of eggs though, so I really shouldn't need extra.
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Do you think Phenyl-Piracetam is another good option? I was thinking of trying that one out as well for other reasons.
 
Gutterpump said:
Do you think Phenyl-Piracetam is another good option? I was thinking of trying that one out as well for other reasons.
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It's been a few years since I last tried that one. If I remember correctly it provided energy and improved mood. It didn't really decrease anxiety or anything. I also developed a tolerance to it after a week or two of taking it continuously (have seen read that is common and it shouldn't be taken every day). I can see how it would be a good one to take on weekends before heading out for a hike or ride.
 
jarrellt67 said:
It's been a few years since I last tried that one. If I remember correctly it provided energy and improved mood. It didn't really decrease anxiety or anything. I also developed a tolerance to it after a week or two of taking it continuously (have seen read that is common and it shouldn't be taken every day). I can see how it would be a good one to take on weekends before heading out for a hike or ride.
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I've read it can be good for people who've down regulated their dopamine receptors through usage of caber/prami, which was why I was wanting to give it a try. Supposedly it can help increase receptor density.
 
Gutterpump said:
I've read it can be good for people who've down regulated their dopamine receptors through usage of caber/prami, which was why I was wanting to give it a try. Supposedly it can help increase receptor density.
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If you decide to try it, please post your results. I'm thinking about trying it again (after aniracetam). I took it with to many other things before (like biotest brain candy) that may have affected the experience.
 
Phenyl-piracetam is awesome i did some tests on how L-dopa effected me prior to Phenyl-Piracetam dosage and post usage and noticed a huge difference in L-Dopa effectiveness, im a big fan of Phenyl-Piracetam but it needs to be cycled.
 
YoungBodyBuil said:
Phenyl-piracetam is awesome i did some tests on how L-dopa effected me prior to Phenyl-Piracetam dosage and post usage and noticed a huge difference in L-Dopa effectiveness, im a big fan of Phenyl-Piracetam but it needs to be cycled.
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Have you tried aniracetam too? If so, how would you compare the two? I liked phenylpiracetam when I tried it before but don't remember everything about how it felt (I have a crappy memory) and was taking other things at the same time.
 
jarrellt67 said:
Have you tried aniracetam too? If so, how would you compare the two? I liked phenylpiracetam when I tried it before but don't remember everything about how it felt (I have a crappy memory) and was taking other things at the same time.
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Yep I do 2 weeks Phenyl Piracetam then 2 weeks aniracetam and do that cycle for 2 months, aniracetem effects dopamine receptor density too im pretty sure
 
Gutterpump said:
Man this is all great info. Thanks guys. Ordering some of both next week
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I'm interested in your experience as I've been looking for something to replace tianeptine, something I can't abuse though (i.e. Ativan), but can use more often than twice a week (i.e. Phenibut).
 
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