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The best Home made GDA

kbayne said:
Me too!!

I need to find a legit source for bulk berberine.
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Not sure if they are still a board sponsor, but SHP sells bulk berberine hcl capped. 400mg x 60 caps per bottle. If you sign up for their mailing list, and time it right, they occasionally have it 30% of regular price plus you can take another 10-20% off with whatever discount code is active during that time. That is when I stock up on the stuff. Comes out to under $6 or less for 24g capped. Pretty good deal and convenient. I order a lot of my basic staples from there as well. Good prices when on sale and e****lent customer service.
 
AKM007 said:
I believe Metformin reduces test in diabetic men....not sure of its effects on the healthy though...
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Metformin can lower IGF-1 levels though, but from what most say.. the benefits outweigh the risk. It has not dropped my igf levels yet.
 
hsk said:
Not sure if they are still a board sponsor, but SHP sells bulk berberine hcl capped. 400mg x 60 caps per bottle. If you sign up for their mailing list, and time it right, they occasionally have it 30% of regular price plus you can take another 10-20% off with whatever discount code is active during that time. That is when I stock up on the stuff. Comes out to under $6 or less for 24g capped. Pretty good deal and convenient. I order a lot of my basic staples from there as well. Good prices when on sale and e****lent customer service.
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Good to know, thanks
 
booneman77 said:
In which case it's chromium, iodine and brown seaweed... I'm not terribly familiar with the last one, but that being the case I have a hard time believing it's anything amazing if none of us have really used it or even seen it in anything else.
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The Brown Seaweed is probably Fucoxanthin - actually has some good data on it for fat loss, and also mediates glucose metabolism in musle tissue. Check Examine. Analyzed had it in Lipovate. It has to be taken continuously for a long time though (5-16 weeks) before benefits are realized.
 
The_Old_Guy said:
The Brown Seaweed is probably Fucoxanthin - actually has some good data on it for fat loss, and also mediates glucose metabolism in musle tissue. Check Examine. Analyzed had it in Lipovate. It has to be taken continuously for a long time though (5-16 weeks) before benefits are realized.
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EBF had it in AAv2 as well I think
 
Good thread!

OP, I just want to say that I think it's e****lent you've found something (particularly with some basic ingredients you're able to assemble on your own for a reasonable price) that has had such an impact for you.

My dad is type 1.5 diabetic (weird auto-immune disorder version that hangs out between the two), so I may try to work on something similar with him.
 
Is Berberine worth adding to my home made GDA?

Using right now with my first meal of the day:

300mg Na-R-ALA
1g Agmatine
2g ALCAR
 
Pec.Major said:
Is Berberine worth adding to my home made GDA?

Using right now with my first meal of the day:

300mg Na-R-ALA
1g Agmatine
2g ALCAR
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Should work very well but I wouldn't dose the Berberine any higher than 400-500mg. Berberine and N R ALA is a potent combo.
 
SlinMax we dose 250mg Na-R-ALA, 750mg Agmatine and 200mg Berberine + Corsolic Acid/4-Hydroxyisoluecine and its very strong GDA, we found with that combo berberine was more then enough at 200mg. As a standalone 500mg may be necessary but with well dosed Na-R-ALA/Agmatine it doesn't seem necessary.
 
MidwestBeast said:
Good thread!

OP, I just want to say that I think it's e****lent you've found something (particularly with some basic ingredients you're able to assemble on your own for a reasonable price) that has had such an impact for you.

My dad is type 1.5 diabetic (weird auto-immune disorder version that hangs out between the two), so I may try to work on something similar with him.
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Problem with **** on these boards? Haha

Edit: guess so
 
Pec.Major said:
Is Berberine worth adding to my home made GDA?

Using right now with my first meal of the day:

300mg Na-R-ALA
1g Agmatine
2g ALCAR
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I personally would only use Berberine a few times a week.

Also, have you thought about splitting up the Agmatine and ALCAR into two 500mg Agmatine and 1000mg ALCAR dosing?
 
kbayne said:
I personally would only use Berberine a few times a week.

Also, have you thought about splitting up the Agmatine and ALCAR into two 500mg Agmatine and 1000mg ALCAR dosing?
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How come, may I ask?

No, I have not thought about it. I am dosing as Mr.Cooper suggest in this thread: Invalid Link Removed

But I do take 1g Agmatine with my post workout meal. So 2g Agmatine ED.
 
Pec.Major said:
How come, may I ask?

No, I have not thought about it. I am dosing as Mr.Cooper suggest in this thread: Invalid Link Removed

But I do take 1g Agmatine with my post workout meal. So 2g Agmatine ED.
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Simply because of Berberine and its effects on AMPK. Also, not personally, but a few well known coaches in the industry have experimented with Berberine and dosing, many of them came back talking how they did not like the way their physique changed from daily dosing of Berberine. They noticed much better body composition by only dosing a few times a week.

But, you could try daily dosing and see if you notice any negatives.

And my bad, I meant splitting the Agmatine and ALCAR up if using another Na-R-ALA dose.
 
The_Old_Guy said:
Cool post. Have you experimented with Apple Cider Vinegar and Cinnamon? The ACV oddly only works when taken before a complex carb meal according to the research. I stopped taking Cinnamon because of the Coumarin and I wasn't going to pay for Ceylon, so I haven't kept up on that research. I'm surprised you haven't looked at Berberine? (There are downsides though with cAMP and Hypertrophy).
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ceylon isnt even that much money, i go through a pound every 2 months its like 16 bucks U cant even by the chit stuff for that cheap in the supermarket
 
carmaf said:
I can attest to this personally, as I have found through my experience with Burn24. The great thing is a few times a week is still enough to see results. Truly a great ingredient/product.



I definitely noticed exactly this. A halting of gains, or even a bit of a step backwards. Regardless, Burn24 was a game changer for me in terms of fat loss, so depends on what your goals are. Nothing good in life comes easy or cheap lol.
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Worst sheeple buzz phrase in recent history. Life was so much better 7-8 years ago when no one was using it for every other sentence.
 
fightnews said:
Worst sheeple buzz phrase in recent history. Life was so much better 7-8 years ago when no one was using it for every other sentence.
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Haha sheeple, that word was a game changer for me during highschool
 
The anti-hypertrophy effects people claim to experience from berberine are more likely to be nocebo
 
Jiigzz said:
Haha sheeple, that word was a game changer for me during highschool
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"make no mistake" is another annoying one everybody had to start saying after Bush said it, they all have to say it with the thumb pointing too
 
Chefdeez said:
Actually berberine has been shown to decrease protein synthesis.
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There comes a time when one must wonder by how much these things occur and to what extent. Especially in humans.

I had read a bit about berberine a long time ago, may need to refresh my memory
 
I've stated this before, but if only using Berberine 1-3 times per week, I wouldn't worry about its negative impact on hypertrophy or body composition via activation of AMPK as long as one is lifting heavy.

If dosing Berberine daily for a longer period of time, it will have a negative impact on body composition. Been listening to quite a few podcasts on some well respected individuals thoughts on Berberine and their anecdotal feedback -- all come back stating once they dropped the frequency of dosing, they noticed much better body composition and performance in the gym.
 
Making chicken ziti with the wife. In the oven now, so I just had some Defuse, Slintensity, NaRALA, and agmatine.

Not home made, but was just going through my subscriptions and seemed appropriate :)

nom nom nom
 
kbayne said:
I've stated this before, but if only using Berberine 1-3 times per week, I wouldn't worry about its negative impact on hypertrophy or body composition via activation of AMPK as long as one is lifting heavy.

If dosing Berberine daily for a longer period of time, it will have a negative impact on body composition. Been listening to quite a few podcasts on some well respected individuals thoughts on Berberine and their anecdotal feedback -- all come back stating once they dropped the frequency of dosing, they noticed much better body composition and performance in the gym.
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Correct. Definitely not something you NEED daily rather than pre cheat meals, etc.
 
so the general consensus is that Berberine is bad for hypertrophy so shouldn't be dosed anywhere near training, and also shouldn't be used daily?

a question for the group but to help the OP...

would it be beneficial to add Gymnema Sylvestre to his current stack of

Na-R-ALA
ALCAR
Agmatine or

would that not be necessary? advantages / disadvantages to doing so? Ill admit Im curious for myself as well.
 
Darkhorse192 said:
so the general consensus is that Berberine is bad for hypertrophy so shouldn't be dosed anywhere near training, and also shouldn't be used daily?

a question for the group but to help the OP...

would it be beneficial to add Gymnema Sylvestre to his current stack of

Na-R-ALA
ALCAR
Agmatine or

would that not be necessary? advantages / disadvantages to doing so? Ill admit Im curious for myself as well.
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I personally would keep Berberine away from training as well as using sparingly throughout the week.

As for Gymnema Sylvester, personally wouldn't add it unless I was looking for something to slow/block absorption of carbohydrates (so maybe during a cut it could play benefit).
 
Jiigzz said:
There comes a time when one must wonder by how much these things occur and to what extent. Especially in humans.
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I feel that way about "GDA"s in general for 9x% of the lifting population. Carbs to Fat is not an easy, efficient process that the body likes to undertake - it much prefers to just store excess dietary fat for the upcoming famine. Large surplus' aside (and forget about deficits/maintenance combined with heavy lifting/cardio), I think the *fear* of De Novo Lipogenesis is greater than the reality.
 
The_Old_Guy said:
I feel that way about "GDA"s in general for 9x% of the lifting population. Carbs to Fat is not an easy, efficient process that the body likes to undertake - it much prefers to just store excess dietary fat for the upcoming famine. Large surplus' aside (and forget about deficits/maintenance combined with heavy lifting/cardio), I think the *fear* of De Novo Lipogenesis is greater than the reality.
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Agreed. Definitely. Sounds like a lyle thing ;)

but then I dont like excess CHO floating in my blood stream constantly, with lipoprotein interaction and all
 
Jiigzz said:
Agreed. Definitely. Sounds like a lyle thing ;)

but then I dont like excess CHO floating in my blood stream constantly, with lipoprotein interaction and all
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Nah, I agree there about constant CHO. I admit it, I'm a research zealot and I'll try out anything that was reasonably conducted. A few months ago I read a pretty good one on Skewed CHO in the AM/Noon and ZERO after that - in reference to the bodies utilization of stored fat. So I've been doing that with success (ie. no performance loss - no idea on fat, what with the 20 other "fat loss" things I take). I also do Apple Cider Vinegar with the AM/Noon (complex) carbs, so I can't say I'm 100% against some sort of "GDA" - just not much more $'s than a bottle of Vinegar and maybe some Ceylon per month :)
 
The_Old_Guy said:
Nah, I agree there about constant CHO. I admit it, I'm a research zealot and I'll try out anything that was reasonably conducted. A few months ago I read a pretty good one on Skewed CHO in the AM/Noon and ZERO after that - in reference to the bodies utilization of stored fat. So I've been doing that with success (ie. no performance loss - no idea on fat, what with the 20 other "fat loss" things I take). I also do Apple Cider Vinegar with the AM/Noon (complex) carbs, so I can't say I'm 100% against some sort of "GDA" - just not much more $'s than a bottle of Vinegar and maybe some Ceylon per month :)
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I see your point though, and im with you on it as well. A CHOs least likely pathway is to be converted into a triglyceride, under normal circumstances. There are caveats, but they arnt ones you'll typically stumble across accidentally.

I do like GDAs on a cut and pre bed though, but I dont consider them something ill spend a lot of money on
 
People like to read studies and talk about protein synthesis that and protein synthesis this - but usually they are focusing on small portions of time and not the big picture. Look at leucine spikes...first you learn how great leucine is because it spikes protein synthesis and then you start taking it multiple times a day, and then you find out that if it's overdone, the spike becomes less and less....so it's better to have infrequent dosing. I wonder if berberine could be used to enhance this effect - i.e. - create more of a deficit so you can create a leucine spike more often.

Note that everything I just said is just me thinking out loud and not based on research....
 
hsk said:
Not sure if they are still a board sponsor, but SHP sells bulk berberine hcl capped. 400mg x 60 caps per bottle. If you sign up for their mailing list, and time it right, they occasionally have it 30% of regular price plus you can take another 10-20% off with whatever discount code is active during that time. That is when I stock up on the stuff. Comes out to under $6 or less for 24g capped. Pretty good deal and convenient. I order a lot of my basic staples from there as well. Good prices when on sale and e****lent customer service.
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Just a heads up... was browsing Swansons. Looks like Berberine is on sale with an additional 15% off right now. Might pull the trigger on these.
 
ronnycjc said:
Just a heads up... was browsing Swansons. Looks like Berberine is on sale with an additional 15% off right now. Might pull the trigger on these.
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Is there a code for the extra 15%?
 
booneman77 said:
Is there a code for the extra 15%?
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Oh if you signed up for their newsletter, they will give you that additional 10-20% discount (not a code, but a special web link sent via email), where it automatically applies the discount to your cart. It's not a code I believe.
 
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