Not the same, no, lol, but I have a genetic mutation of MTHFR so I speak from experience.
However, it takes a few grams of betaine HCL to feel a little burn with 8oz of meat down the hatch so it is likely that I don't make any stomach acid at all. I do take NOW SuperEnzymes in addition to the above. Now solid protein food at least gets worked over some before travelling further down but I doubt liquid protein mess gets the same treatment, especially because I don't take HCL with those to lessen the burn.
If you read up on Poliquin's piece on HCL he claims that 1 or 2 out 250 guys he sees pass the HCL test (with one of them being a writer, lower stress I would imagine). I prefer not to have opinions when I have some data to work with so here is that.
Now back to the subject of body composition, I can't get really lean without doing intervals. Back then I was buying whey isolate and complete milk dairy isolate in bulk to drink plain and I found it did not make much difference where is mattered most: recovery, strength and lastly mass. I even went up to 3g per lb for a while and that resulted in unexpected strength gains (training DC) and weight and fat loss. Not a good idea long term but even short term all that poorly digested protein inflames the gut and my body can't seem to keep up with fixing the damage from exercise and from nutritional intake. Maybe I am a descendant of a tribe of emaciated vegans, lol. Anyway, I would lose strength and muscle from the intervals and it wasn't pretty.
Fast forward to today, I can do intervals 3 times a week and train legs 3 times in 2 weeks and add 10lbs for 10 on squats every 6-week training rotation. And that's mainly from taking a serving or two of a naturally bitter predigested mess after each training and interval session. Yes, I have read the study where the peptides from the hydro whey were mainly taken up by the splanchnic bed and not muscle in stark contrast with whey isolate which favored muscle over organ uptake. But as Mark Wahlberg said in The Gambler "Physiology doesn't lie" and the hydro stuff works for me much better than the good plain powder (and better than single aminos) in spite of what the study says and in spite of what everyone, including me, thinks should work better.
Regards