The Arachidonic Acid Help Guide

It's a fat soluble vitamin that inhibits nitrosation
 
Spaniard said:
Hey buddy, quick Q for you or @Invalid Link Removed @Invalid Link Removed. Any worries of taking this or GMS (frequently stacked with ArA) with a Nitrate product containing vitamin C? I've read multiple recommendations for doing so but wouldn't that encourage nitrosation due to the presence of lipids? It seems like ascorbic acid benefits to halt nitrosation are completely reversed in the presence of lipids. Not only reversed but carcinogenic. I called a few pharmacies but as usual they had no clue what I was talking about lol

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If this is dependent upon the ascorbic acid, which many companies add to their nitrate product, would pomegranate be able to be used as an antioxidant in the place of vitamin C?
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I would just use your nitrate product at a different time, or try your best to find a nitrate product without vitamin C if you're worried, although IMO it won't be an issue at the doses usually involved. No point in using pomegranate. I would advise against using vitamin E if you don't need it as well.
 
Synapsin said:
I would just use your nitrate product at a different time, or try your best to find a nitrate product without vitamin C if you're worried, although IMO it won't be an issue at the doses usually involved. No point in using pomegranate. I would advise against using vitamin E if you don't need it as well.
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Thank you, sir. After I looked a little deeper I started to question vitamin E. Do you mind briefly explaining why you don't advise the use of it?
 
Spaniard said:
Thank you, sir. After I looked a little deeper I started to question vitamin E. Do you mind briefly explaining why you don't advise the use of it?
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Research on it is generally mixed but the latest studies (as of this year) indicate excessive vitamin e may be a cancer risk in men. There is no danger of toxicity or anything like that though.
 
Spaniard said:
Thank you, sir. After I looked a little deeper I started to question vitamin E. Do you mind briefly explaining why you don't advise the use of it?
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Did he or she talk back to you?. Did you slam him around a bit to get to the truth?. Maybe turn up the heat and leave the room for a bit. Bring in a big tall glass of ice water and drink it in front of him or her. That'd get to the truth.
 
Going to throw in my stupid questions in restated form here, given that I'm getting itchier and itchier to stack in my ArA into my old-formula-ABE run (loving that anacyclus so far!):

  1. Ignoring glycerol's standalone benefits, would soy lecithin (or another emulsifier) serve the same purpose as GMS in enhancing ArA availability?
  2. Given that amentoflavone has putative anti-inflammatory properties, should it be avoided alongside ArA, or is this of little concern?
  3. Any easy alternatives to lodhra for lipoxygenase inhibition, given I'm on old ABE? Compound 20 is the only standalone I can find that isn't straight out of India, and it's practically as expensive as a brand spankin' new bottle of ABE.

Thanks!
 
Nyrin said:
Going to throw in my stupid questions in restated form here, given that I'm getting itchier and itchier to stack in my ArA into my old-formula-ABE run (loving that anacyclus so far!):

  1. Ignoring glycerol's standalone benefits, would soy lecithin (or another emulsifier) serve the same purpose as GMS in enhancing ArA availability?
  2. Given that amentoflavone has putative anti-inflammatory properties, should it be avoided alongside ArA, or is this of little concern?
  3. Any easy alternatives to lodhra for lipoxygenase inhibition, given I'm on old ABE? Compound 20 is the only standalone I can find that isn't straight out of India, and it's practically as expensive as a brand spankin' new bottle of ABE.

Thanks!
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1. It can, but it will be inferior for this purpose.
2. No issue there
3. There's silymarin but it has poor bioavailability. Boswellia also his anti-LOX activity but also has mild COX inhibition
 
mr.cooper69 said:
1. It can, but it will be inferior for this purpose.
2. No issue there
3. There's silymarin but it has poor bioavailability. Boswellia also his anti-LOX activity but also has mild COX inhibition
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Thanks for the quick reply, Coop. I'll try to snag some GMS, not shy away from stacking the amento, and consider boswellia while I try to scrounge up some lodhra. I'm sure it's all sweating the small stuff anyhow, but hey, why not?
 
Synapsin said:
Research on it is generally mixed but the latest studies (as of this year) indicate excessive vitamin e may be a cancer risk in men. There is no danger of toxicity or anything like that though.
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Thanks again
T-Bone said:
Did he or she talk back to you?. Did you slam him around a bit to get to the truth?. Maybe turn up the heat and leave the room for a bit. Bring in a big tall glass of ice water and drink it in front of him or her. That'd get to the truth.
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I did good cop, bad cop. Works every time :p
 
Quick question:

About how long would it take to see if x gels gives me inflammatory side effects? I have a mild arthritic condition that is pretty well in check. Like would I be able to tell in a couple doses If I can or can't tolerate the stuff? I really wanna try it due to all the great results and science behind it... At least see how it treats me before I say " I CAN'T take this.." Ideas?
 
chedapalooza said:
Quick question:

About how long would it take to see if x gels gives me inflammatory side effects? I have a mild arthritic condition that is pretty well in check. Like would I be able to tell in a couple doses If I can or can't tolerate the stuff? I really wanna try it due to all the great results and science behind it... At least see how it treats me before I say " I CAN'T take this.." Ideas?
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Really?

chedapalooza said:
Doctor told me to steer clear bc of inflammatory medical conditions i have. Wanted to give them a run but he said it would be a horrible mistake.. So selling or trading. Pm me
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chedapalooza said:
Quick question:

About how long would it take to see if x gels gives me inflammatory side effects? I have a mild arthritic condition that is pretty well in check. Like would I be able to tell in a couple doses If I can or can't tolerate the stuff? I really wanna try it due to all the great results and science behind it... At least see how it treats me before I say " I CAN'T take this.." Ideas?
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2 weeks although I wouldn't advice doing it just in case.
 
chedapalooza said:
Quick question:

About how long would it take to see if x gels gives me inflammatory side effects? I have a mild arthritic condition that is pretty well in check. Like would I be able to tell in a couple doses If I can or can't tolerate the stuff? I really wanna try it due to all the great results and science behind it... At least see how it treats me before I say " I CAN'T take this.." Ideas?
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That's a really bad approach to this dude. Try it and stop if you get a flareup? This is your health man, you know, the most important thing in your life, and you really need to start prioritizing it my friend
 
chedapalooza said:
Yea really. Doctors misdiagnose and cover their asses all the time without actually knowing wtf they r taking about. I've seen enough to know some of them are pretty fckin lazy and stupid
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Stereotyping is ignorant. Don't be ignorant. If you really feel your doctor is such a POS, why do you see him? You have a whole world of doctors to choose from
 
mr.cooper69 said:
Stereotyping is ignorant. Don't be ignorant. If you really feel your doctor is such a POS, why do you see him? You have a whole world of doctors to choose from
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Im not stereotyping, just speaking from what i have experienced. I've gone to several doctors with symptoms and they all say its nothing, they do nothing, then the symptoms get progressively worse. Four years later, I am layed out with a pinched nerve and pelvis and joint alignment issues all over the place... Why? Bc no one could take the damn time to figure out what I was spoon feeding them for symptoms

I have seen probably 10 doctors over the last 8 years for a variety of things. They've all been essentially useless except for one, who, in the end, prescribed me a dangerous combination of antibiotics (quinolone class) and NSAID (meloxicam) which have been proven to be quite dangerous when combined- the kicker? He didn't even test me for an infection... Just prescribed a heavy duty Antiobiotic on a whim.

It must just be me! How many threads on this forum are about doctors using outdated methods and practices and information? Especially regarding fitness, diet, and HRT? I'm not the only one.

Unfortunately this whole place has become overrun with people who think they know everything, when only a few do. Criticism from you is one thing, bc we have an extensive relationship on here which I am thankful for. But in general... Too many people here trying to pass their own anecdotal observations off as fact.

I take my health very seriously which is why I get very frustrated when I present a problem to a professional and they brush It off bc I am young and "healthy looking"
 
But whatever I'm not gonna derail the thread anymore. No one gives a **** in real life and I don't expect it to be any different here. Ill just observe and keep my delusional thoughts and opinions to myself
 
chedapalooza said:
Im not stereotyping, just speaking from what i have experienced. I've gone to several doctors with symptoms and they all say its nothing, they do nothing, then the symptoms get progressively worse. Four years later, I am layed out with a pinched nerve and pelvis and joint alignment issues all over the place... Why? Bc no one could take the damn time to figure out what I was spoon feeding them for symptoms

I have seen probably 10 doctors over the last 8 years for a variety of things. They've all been essentially useless except for one, who, in the end, prescribed me a dangerous combination of antibiotics (quinolone class) and NSAID (meloxicam) which have been proven to be quite dangerous when combined- the kicker? He didn't even test me for an infection... Just prescribed a heavy duty Antiobiotic on a whim.

It must just be me! How many threads on this forum are about doctors using outdated methods and practices and information? Especially regarding fitness, diet, and HRT? I'm not the only one.

Unfortunately this whole place has become overrun with people who think they know everything, when only a few do. Criticism from you is one thing, bc we have an extensive relationship on here which I am thankful for. But in general... Too many people here trying to pass their own anecdotal observations off as fact.

I take my health very seriously which is why I get very frustrated when I present a problem to a professional and they brush It off bc I am young and "healthy looking"
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Well just so ya know. I've had similar experiences with doctors. One doctor I had..made a decision to put me on something that altered the course of my life. Everything was great in my life until he did this and it still (a)effects me to this day. For awhile people were calling me crazy until I got 2nd, 3rd, 4th opinions then finally someone said "wow is your doctor a ****ing moron" then things got gradually better
 
I just got braces and my teeth are hurting like a motherfckr. Would the x-factor cause my soreness to last longer? I love x-factor but when I can't even eat, I'm not getting all the gains I need
 
chedapalooza said:
But whatever I'm not gonna derail the thread anymore. No one gives a **** in real life and I don't expect it to be any different here. Ill just observe and keep my delusional thoughts and opinions to myself
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I would just take a few deep breaths, ched. In general, i've seen you over the past few years struggling with different issues, which can be frustrating, understandably so.

I recommend that you try to be more assertive with your doctor. If you aren't happy with that doc, find another. Remember, these guys work for you, bro. If they give you an abx without something that you think is necessary ask them about it. A lot of your frustrations can be solved by speaking up and being a little more inquisitive. I realize physicians can be a little hurried during the exams but they're trying to see a bunch of people, which doesn't make it right. That's where you have to try to control the conversation to make sure you are satisfied when you walkout of there. Treat it like buying a car. Are you going to let them sell you a VW beetle for 200 k? No, you would speak up. Who knows maybe they got a little complacent, no one is in entirely immune to complacency.

The next time you have an issue, speak up. If they recommend something, ask why. Ask why they are deciding to forego a test and just prescribe something. A lot of times with abx they are prescribing something that will take care of what it might be (with little to no worry of side effects) vs sending you to get labs drawn, then getting the results, then having you come back and finally treating the problem, which could've just been handled with an Rx in the first place. If you prefer to go through the process, tell them you'd rather skip just taking the pill and have some tests done.

Yes, some practitioners prescribe a little too frequently. Yes, some practitioners are using archaic methods for TRT. Yes, a lot of docs don't know **** about supps. This does not mean that we dismiss the knowledge of the medical community entirely. Nor do we go around continuing the spread of distrust in our practitioners. What this ultimately boils down to is if you are not getting the care you desire after seeing 8 docs you see 9, 10, 11 or 15. Don't give up its your health. Once you get to 30 though I think it's safe to say you're a pain in the ass ;)

Good luck bro, like Coop said, it's your health. You only go around once, it's not worth the risk for a few pounds of muscle.
 
chedapalooza said:
Im not stereotyping, just speaking from what i have experienced. I've gone to several doctors with symptoms and they all say its nothing, they do nothing, then the symptoms get progressively worse. Four years later, I am layed out with a pinched nerve and pelvis and joint alignment issues all over the place... Why? Bc no one could take the damn time to figure out what I was spoon feeding them for symptoms

I have seen probably 10 doctors over the last 8 years for a variety of things. They've all been essentially useless except for one, who, in the end, prescribed me a dangerous combination of antibiotics (quinolone class) and NSAID (meloxicam) which have been proven to be quite dangerous when combined- the kicker? He didn't even test me for an infection... Just prescribed a heavy duty Antiobiotic on a whim.

It must just be me! How many threads on this forum are about doctors using outdated methods and practices and information? Especially regarding fitness, diet, and HRT? I'm not the only one.

Unfortunately this whole place has become overrun with people who think they know everything, when only a few do. Criticism from you is one thing, bc we have an extensive relationship on here which I am thankful for. But in general... Too many people here trying to pass their own anecdotal observations off as fact.

I take my health very seriously which is why I get very frustrated when I present a problem to a professional and they brush It off bc I am young and "healthy looking"
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I'm sorry for your situation, but you've seen 10 doctors. That's a very low sample size. I'm not even done my education and I've interacted at length with maybe 200 physicians + another hundred interns and residents. There are DEFINITELY some of those doctors who I'd never want taking care of my health, but there are also many others who I've observed going the extra mile and beyond to make sure a patient is satisified.

So yes, calling all doctors misdiagnosing idiots is absolutely stereotyping. The 10 you have worked with may fall in that category, but to call everyone who basically sacrifices a large portion of their lives to go into this field a bunch of morons is very, very ignorant.
 
mr.cooper69 said:
I'm sorry for your situation, but you've seen 10 doctors. That's a very low sample size. I'm not even done my education and I've interacted at length with maybe 200 physicians + another hundred interns and residents. There are DEFINITELY some of those doctors who I'd never want taking care of my health, but there are also many others who I've observed going the extra mile and beyond to make sure a patient is satisified.

So yes, calling all doctors misdiagnosing idiots is absolutely stereotyping. The 10 you have worked with may fall in that category, but to call everyone who basically sacrifices a large portion of their lives to go into this field a bunch of morons is very, very ignorant.
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Fair enough. I'm not an ignorant person and I wouldn't say that ALL doctors are morons; that is clearly a moronic and ignorant statement. If my initial comments came across as encompassing the entire medical professional field, then that wasnt my intention
 
chedapalooza said:
Fair enough. I'm not an ignorant person and I wouldn't say that ALL doctors are morons; that is clearly a moronic and ignorant statement. If my initial comments came across as encompassing the entire medical professional field, then that wasnt my intention
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Yeah I didn't say you were ignorant; rather, I was saying you're not an ignorant person so don't let your experiences lead you to make statements that are out of character. I mean I'm not the biggest fan of police officers in my experience, but there are plenty who are good people and I'd never put them down as a whole.

Back on topic, I don't think you should chance ArA bro
 
Hey Coop did you see my mention from a few pages back in regards to the studies I posted on ARA and ulcers? Just looking for your opinion, thanks!
 
mr.cooper69 said:
Yeah I didn't say you were ignorant; rather, I was saying you're not an ignorant person so don't let your experiences lead you to make statements that are out of character. I mean I'm not the biggest fan of police officers in my experience, but there are plenty who are good people and I'd never put them down as a whole.

Back on topic, I don't think you should chance ArA bro
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Then I think you should formulate something to give me the gains everybody else is getting with x ara!!
 
Just did some quick reading about ara in foods. I eat a lot of gluten free rolled oats and gluten free steel cut oats - do these forms still contain ara and inflammatory properties?
 
chedapalooza said:
Just did some quick reading about ara in foods. I eat a lot of gluten free rolled oats and gluten free steel cut oats - do these forms still contain ara and inflammatory properties?
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unfortunately I'm in the same boat as you. Have two bottles of X factor and anabeta sitting in my drawer. Doc said I have costochondritis so I guess I won't be using either :( not worth the health risk bro. I'll be posting mine up on the traders thread as well shortly.
 
Afi140 said:
unfortunately I'm in the same boat as you. Have two bottles of X factor and anabeta sitting in my drawer. Doc said I have costochondritis so I guess I won't be using either :( not worth the health risk bro. I'll be posting mine up on the traders thread as well shortly.
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feel free to send them my way. ;)

In all seriousness, hit me up for trade info
 
Afi140 said:
unfortunately I'm in the same boat as you. Have two bottles of X factor and anabeta sitting in my drawer. Doc said I have costochondritis so I guess I won't be using either :( not worth the health risk bro. I'll be posting mine up on the traders thread as well shortly.
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What does the Anabeta do to that?
 
chedapalooza said:
What does the Anabeta do to that?
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should have clarified. Not using either of my X factor bottles. Lo Siento. Bummed too but just gonna look more into pa or follidrone
 
For ulcers, run this by your physician but the primary causes of ulcers are severe stress (i.e. burns), NSAIDs, excessive acid production, and most importantly, H. pylori infection. Prostaglandins are actually PROTECTIVE against ulcers and the reason that NSAIDs cause ulcers is by blocking prostaglandin formation. ArA is the precursor to the protective prostaglandins. So I personally see no issue, but run it by your doctor.

ArA can, however, absolutely cause diarrhea
 
mechka_grizli said:
The dose of Omega 3's in XFA is very small compared to the dose on woukd take on a daily basis. However, it has been shown that the added omega 3's actually syngerize with ARA as it displaces ARA and allows more to circulate through the system. (In simplified terms)
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This is a very bad thing. You do not want to displace ArA from the membrane. The whole point of all of this is to deliver it to the muscle cell, not send it to the cell then kick it back out into circulation.
 
mr.cooper69 said:
For ulcers, run this by your physician but the primary causes of ulcers are severe stress (i.e. burns), NSAIDs, excessive acid production, and most importantly, H. pylori infection. Prostaglandins are actually PROTECTIVE against ulcers and the reason that NSAIDs cause ulcers is by blocking prostaglandin formation. ArA is the precursor to the protective prostaglandins. So I personally see no issue, but run it by your doctor.

ArA can, however, absolutely cause diarrhea
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Thank you very much for clarifying that.

Now ArA causing diarrhea is that because I do in fact have an ulcer or is diarrhea simply a side effect of ArA for some people, and would lowering the dosage help?
 
mr.cooper69 said:
This is a very bad thing. You do not want to displace ArA from the membrane. The whole point of all of this is to deliver it to the muscle cell, not send it to the cell then kick it back out into circulation.
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That's why I remain confused. The great results were from studies using the original XFactor, correct? Did I make a mistake going with the Advanced formula?

PS--As a physician myself, I appreciate the well reasoned replies that you and Spaniard gave earlier. Thanks.
 
mr.cooper69 said:
That's a really bad approach to this dude. Try it and stop if you get a flareup? This is your health man, you know, the most important thing in your life, and you really need to start prioritizing it my friend
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Hey Coop, remember when all the lazy idiots breezed through med school easily and went on to be doctors?

Me either.
 
mechka_grizli said:
The dose of Omega 3's in XFA is very small compared to the dose on woukd take on a daily basis. However, it has been shown that the added omega 3's actually syngerize with ARA as it displaces ARA and allows more to circulate through the system. (In simplified terms)
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SheddingSkin said:
Thank you very much for clarifying that.

Now ArA causing diarrhea is that because I do in fact have an ulcer or is diarrhea simply a side effect of ArA for some people, and would lowering the dosage help?
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Ulcers don't cause diarrhea; the effect is independent

jacksonian said:
That's why I remain confused. The great results were from studies using the original XFactor, correct? Did I make a mistake going with the Advanced formula?

PS--As a physician myself, I appreciate the well reasoned replies that you and Spaniard gave earlier. Thanks.
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The original is undoubtedly superior, but you aren't losing too hard with XFA, it should be only mildly less potent

De__eB said:
Hey Coop, remember when all the lazy idiots breezed through med school easily and went on to be doctors?

Me either.
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chedapalooza said:
;) I'm sure med school is hard. But complacency is the issue, not intelligence.
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I'd argue that hard work gets you through moreso than intelligence ;)
 
Been on X-gels and ABE for a little over 2 weeks now at 1g ArA doses, with an increase in kcal of about 200, but have not really noticed much. Should I increase to 1.5g doses? This is my first time on both products. I am 22, weight fluctuates around 176-180, and 5'9". My nutrition is on point, total kcals range from 3500-3700 (250-270g PRO, 350-400g CHO, and 125-150g FAT). Haven't really noticed any changes in weight either, should I increase CHO further?

Other supplementation includes:
- vitamin D3
- Hemavol
- Agmatine
- PN
- caffeine
- ALCAR
- GlycerGrow
- TMG
- protein + leucine
- Core ABC intra
- beta alanine
- creatine mono
- ZMA

Stopped taking fish oil and Flexible (has Cissus), so I don't see any contraindications with anything else.

I began dosing as directed, 45 min pre with pre about 15 mins later, but I tried both at the same time about 20-30 mins pre and prefer that better.

Strength gains have been minimal at best (I do a linear periodized scheme, and then stay at higher weights and do a week or two of pyramids at low RMs before jumping back up) maybe I'm expecting too much too quick. Any suggestions are appreciated.
 
Being it's only been about 2 weeks, give it more time.
 
ArA was worthless to me at less than 2g. Not that I want to think of the price/dose, but are there diminishing returns at more than 2g or something?

GMS: Are you cats parachuting this? How are you choking this back?
 
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