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7-KETO or NA-R-ALA?

The beta hydroxyisomer does appear to be the one correlated with the thyroid and cognative boosting effects

I'll look more into it.

Anabeta e. contains just the 7 beta isomer
 
jbryand101b said:
Not sure, maybe some brighter minds than I can point out studies with benifits of 7b hydroxyl dhea
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Still teaching me plenty man, thanks ;) . So ABE has 7-beta-hydroxy-dhea? And 7-alpha-hydroxy-dhea is a different compound that does convert to 7-beta-hydroxy-dhea but also to 7-oxo?
 
tyrub42 said:
Still teaching me plenty man, thanks ;) . So ABE has 7-beta-hydroxy-dhea? And 7-alpha-hydroxy-dhea is a different compound that does convert to 7-beta-hydroxy-dhea but also to 7-oxo?
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yes, but conversion is more so useful for competitive inhibition of the enzyme that converts cortisone to cortisol.
 
7b hydroxy dhea is the strongest inhibitor of 11-hsd1 actually (ic50 data). The guys who you quoted, jbry (ds I presume), are quite incorrect.

As for ephedrine, repeated human trials all show an increase in net weight loss, with more weight coming from fat and less coming from muscle. This is indeed the definition of a muscle sparing effect. I'm not comparing it to hormones by any means, but the effect is real. B2 agonism results in triglyceride catabolism in adipose tissue and a protein-sparing effect in skeletal muscle. A more extreme example would be clen, which people regularly use for its anti catabolic properties while cutting.
 
mr.cooper69 said:
7b hydroxy dhea is the strongest inhibitor of 11-hsd1 actually (ic50 data). The guys who you quoted, jbry (ds I presume), are quite incorrect.

.
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That is who I quoted I think can't see digs on my phone, so don't know if it was a rep or not.

Searching studies, I wasn't able to find anything specifically on beta version.
If you know of them, I would appreciate a link so I can read.
 
jbryand101b said:
That is who I quoted I think can't see digs on my phone, so don't know if it was a rep or not.

Searching studies, I wasn't able to find anything specifically on beta version.
If you know of them, I would appreciate a link so I can read.
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Epimerase activity of the human 11-hydroxysteroid dehydrogenase type 1 on
7-hydroxylated C19-steroids

If you read the full text, the 7 beta isoform is the most potent and biologically valuable of the hydroxylated derivatives.
 
6 caps of reduce xt a day? Jesus that would get expensive. Can't believe that would really be necessary
 
mr.cooper69 said:
They all interconvert FYI. It is in fact the original 7-keto that promotes thyroid function:

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Thanks, Coop! So if I am understanding this correctly, the alpha and beta versions both do pretty much the same thing, as they both convert to each other (and 7-keto) in the body?

And please confirm whether or not ABE uses the beta version of 7-oh.

Oh, since you are a PES rep, can you comment on what dosage of Reduce XT would be roughly equivalent to 4 ABE?

Thanks!
Tyler
 
tyrub42 said:
Thanks, Coop! So if I am understanding this correctly, the alpha and beta versions both do pretty much the same thing, as they both convert to each other (and 7-keto) in the body?

And please confirm whether or not ABE uses the beta version of 7-oh.

Oh, since you are a PES rep, can you comment on what dosage of Reduce XT would be roughly equivalent to 4 ABE?

Thanks!
Tyler
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ABE uses the beta form. I will not comment on the latter because that would be utilizing info from my days at SNS, which is unethical to say the least.
 
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7b-hydroxy dhea can convert into 7b-hydroxy dhea? mind=blown

/endanalassh0lemode
 
mr.cooper69 said:
ABE uses the beta form. I will not comment on the latter because that would be utilizing info from my days at SNS, which is unethical to say the least.
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Sorry for bumping an old thread. However, does anybody know whether the absence of 7 BETA-HYDROXY DHEA in the new ABE formula is because this substance brought no real advantage?
 
jbryand101b said:
ephedrine, ephinephrine, methamphetamines, all cause a catabolic response within the body. they are not anabolic.

I understand the science and technical of what you are saying. but in reality, I am pretty set on believing ephedrine to be a catabolic hormone when all is said and done, as it's catabolic effects in my opinion out weigh any anti catabolic properties it might show.
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Ive never noitced muscle loss from e/c/a. Ive used it to recomp numerous times. Now t3 on the otherhand is catabolic at large doeses and It did make me lose strenght quicker than normal.
 
MaXopA said:
Sorry for bumping an old thread. However, does anybody know whether the absence of 7 BETA-HYDROXY DHEA in the new ABE formula is because this substance brought no real advantage?
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I do know, and no, that isn't the reason. It's because we had too much cortisol control appearing in too many places and wanted to streamline the lineup. 7-b-OH does work and can still be found in Reduce XT
 
mr.cooper69 said:
I do know, and no, that isn't the reason. It's because we had too much cortisol control appearing in too many places and wanted to streamline the lineup. 7-b-OH does work and can still be found in Reduce XT
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Indeed with Abe being stacked with erase all the time, you were killing cortisol. And cortisol gets a bad wrap but its a vital hormone.
 
EatMoar said:
Indeed with Abe being stacked with erase all the time, you were killing cortisol. And cortisol gets a bad wrap but its a vital hormone.
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so your suggestion would be not to take them together? I have planned to stack ABE (old version) / EP / DAA. The latter is said to raise estrogen levels, so maybe it could increase cortisol too?
 
MaXopA said:
so your suggestion would be not to take them together? I have planned to stack ABE (old version) / EP / DAA. The latter is said to raise estrogen levels, so maybe it could increase cortisol too?
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You can certainly stack them. Plenty of people have stacked them with great results. The two combined are not going to kill cortisol to such a bad level.
 
kbayne said:
You can certainly stack them. Plenty of people have stacked them with great results. The two combined are not going to kill cortisol to such a bad level.
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well, we all know that cortisol is actually not such a catastrophic hormone, as it brings along not only catabolism in terms of muscle, but also of fat. so if we you're slashing it, you will probably cause a slowdown of fatty oxidation too.
 
MaXopA said:
well, we all know that cortisol is actually not such a catastrophic hormone, as it brings along not only catabolism in terms of muscle, but also of fat. so if we you're slashing it, you will probably cause a slowdown of fatty oxidation too.
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11b-hsd1 inhibition is not the same as lowering systemic cortisol
 
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