epstaneman said:LIVER TEST RESULTS
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Well, I'm going to have to do some more reading/researching and then make my decision.
It's between going one more week to finish up one complete bottle of ep-stane, or call it quits after today to save my liver for the damage Nolvadex is going to do to it. In the mean time, if anyone has anything to chime in, please do.
I'ma go do some more reading....
I expect my liver values to be elevated due to using a methylated compound. I also have seen other peoples levels much higher and they seem to have turned out fine. As far as the elevation combined with a swollen gland, it's got my attention more so. If I do have to end the cycle I won't be one to complain. I've made some pretty sweet a*s gains in these 3 weeks off epistane. More then I thought I would. I thought I was going to have to run this for 8 weeks to be 'happy' so to speak. Looks like if anything, I'll have the second bottle saved for next cycle.
How bad are you to your liver off cycle if you don't my asking, also do you think pre loading with milk thistle would've helped or did you do that? Im bummed for you bro but I'm glad you have enjoyed it this far
loafy777 said:First off, sorry to hear about this man. I know that you were enjoying it.
Secondly, Dr. Plunk? That's a pretty sweet name.
...and finally, here is an excerpt from Livestrong containing a few things that may help mitigate the elevated levels (they are pretty straight forward, but whatever):
[*]Take diuretics as prescribed by your physician. Diuretics remove excess fluid from the body. Your physician might prescribe antibiotics if you have cirrhosis or a liver problem caused by an infection.
[*]Stop drinking alcohol immediately. Alcohol use can cause liver diseases, like cirrhosis and alcoholic hepatitis. Do not drink alcohol after you have recovered.
[*]Eat a special diet. A low-protein diet will reduce the risk of toxins building up in the body due to the liver's inability to process protein correctly. You should eat a high-carbohydrate diet. Avoid salt, as sodium causes swelling and fluid build-up in the liver. Your doctor might suggest vitamins and supplements to make up for those lost by liver dysfunction. Avoid eating shellfish if you have cirrhosis of the liver, as shellfish can contain bacterium that can cause serious infection.
Hopefully the test was just done so closely to you hitting the gym that everything was still elevated from the workout. In either case, good luck man. Keep us posted.
First off, sorry to hear about this man. I know that you were enjoying it.
Secondly, Dr. Plunk? That's a pretty sweet name.
...and finally, here is an excerpt from Livestrong containing a few things that may help mitigate the elevated levels (they are pretty straight forward, but whatever):
- Take diuretics as prescribed by your physician. Diuretics remove excess fluid from the body. Your physician might prescribe antibiotics if you have cirrhosis or a liver problem caused by an infection.
- Stop drinking alcohol immediately. Alcohol use can cause liver diseases, like cirrhosis and alcoholic hepatitis. Do not drink alcohol after you have recovered.
- Eat a special diet. A low-protein diet will reduce the risk of toxins building up in the body due to the liver's inability to process protein correctly. You should eat a high-carbohydrate diet. Avoid salt, as sodium causes swelling and fluid build-up in the liver. Your doctor might suggest vitamins and supplements to make up for those lost by liver dysfunction. Avoid eating shellfish if you have cirrhosis of the liver, as shellfish can contain bacterium that can cause serious infection.
Hopefully the test was just done so closely to you hitting the gym that everything was still elevated from the workout. In either case, good luck man. Keep us posted.
Red9 said:Looks like loafy777 took your avatar Cokeholio ! Yikes
Man I'm sorry to hear that. Thats a real tough decision. Maybe lower the dosage a little, tweak your diet to a very liver friendly one and go get another test next week? This has defintely prompted myself to go get my levels checked out.
Very interesting stuff man, thanks for the great log. I was actually running about the same thing (LGI epi instead up to 40mg). I ended up 'bailing' on Epi at week three as well due to GI issues. I believe it was something to due with the bonded sulfur in epi (possibly minor intolerance/allergy). Finishing up week 4 myself (Bridged to Dimethazine at week 3) and will have bloods done for the change.
In comparsion my AST=22 ALT=22 pre-cycle. Still making all kindz of gainz, here.
Good luck in PCT!
epstaneman said:Stupid sulfur.
This whole thing has thrown up a red flag for me. I remember having a severe allergic reaction to "sulfa-antibiotics" and was out of work for a couple days. After thinking about this, I thought well $hit I hope since Epi is a sulfur compound that I'm not allergic to this. It appears that there IS a difference though in NON antibiotic sulfa compared to prescribed antibiotics. I think I will be fine. Question though: did you experience any sort of skin rash at any time? And yes you might want to check for the self-induced Hepatitis because it shows that sulfa may cause liver failure and Hep. Here's two of the links I've been reading:
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You could still run the Epistane anyway. Just make the most of your cycle by training hard, smart, and eating loads of food. This way in case you have to stop the cycle, you'll make some pretty decent gains while on.
If you don't have signs like pale stools, dark urine, yellow skin/eyes, then your liver isn't damaged to a state of jaundice. However my HEP-C test I'm getting will help me know for sure how damaged it is. This will help sway my judgement on my Nolvadex dosing, as Nolvadex plays a toll on the liver too.
Try a different liver supplement then just milk thistle. Which most supports include. Try a superior alternative. I should of used Live.52 which I know is awesome. Just didn't get it this cycle. Figured the AI life support and milk thistle would be enough. Definitly recommend live.52, drinking plenty of water, and make the most of your cycle every day in case you do experience any sides due to the sulfur.
I didn't get any rash's or anything of that nature. What I got was a swollen node/gland. On my left side under my ear. Painful only to the touch. This means my body is reacting to some type of infection. Could be something even as little as flue or a allergy infection. The one thing it can be at worst is liver damage to a bad degree. So in this respect it's the one I did bloods concerning. The fact it's methyl or the sulfar....either way my liver was getting stressed too much.
Well phuck, now you have me worrying. I had a minor sore throat and a couple swollen nodes in my neck a week ago but everything went away within 12 hours. I woke up this morning feeling achy all over as well.
I wouldn't worry too much. A swollen node just means your body is under attack. It obviously was from the sore throat. Ph's weaken the immune system so you can even catch a fever easily. It's just your body reacting. I just get bloods done because it's safe to know I can cross 'liver toxicity' off the list. During the process figured it was stressing my liver pretty good.
I'm happy with the results I got though. Definitely bigger then when I started.
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You're hilarious man. Good luck with pct.
For all your bloods, did you keep going to your regular doc and request what to screen for? Or did you tell him what you're up to?
READING AST/ALT ON LIVER BLOOD WORK
How is it used?
The alanine aminotransferase (ALT) blood test is typically used to detect liver injury. It is often ordered in conjunction with aspartate aminotransferase (AST) or as part of a liver panel to screen for and/or help diagnose liver disease. AST and ALT are considered to be two of the most important tests to detect liver injury, although ALT is more specific than AST. Sometimes AST is compared directly to ALT and an AST/ALT ratio is calculated. This ratio may be used to distinguish between different causes of liver damage.
ALT values are often compared to the results of other tests such as alkaline phosphatase (ALP), total protein, and bilirubin to help determine which form of liver disease is present.
ALT is often used to monitor the treatment of persons who have liver disease, to see if the treatment is working, and may be ordered either by itself or along with other tests for this purpose.
When is it ordered?
A doctor usually orders an ALT test (and several others) to evaluate a person who has symptoms of a liver disorder. Some of these symptoms include:
Weakness, fatigue
Loss of appetite
Nausea, vomiting
Abdominal swelling and/or pain
Jaundice
Dark urine, light colored stool
Itching (pruritus)
ALT may also be ordered, either by itself or with other tests, for people who are at an increased risk for liver disease. Some examples include:
Persons who have a history of known or possible exposure to hepatitis viruses
Those who are heavy drinkers
Individuals whose families have a history of liver disease
Persons who take drugs that might occasionally damage the liver
Persons who are overweight and/or have diabetes
In persons with mild symptoms, such as fatigue or loss of energy, ALT may be tested to make sure they do not have chronic liver disease.
When ALT is used to monitor the treatment of persons who have liver disease, it may be ordered on a regular basis during the course of treatment to determine whether the therapy is effective.
What does the test result mean?
Normally, levels of ALT in the blood are low.
Very high levels of ALT (more than 10 times the highest normal level) are usually due to acute hepatitis, often due to a virus infection. In acute hepatitis, ALT levels usually stay high for about 1–2 months but can take as long as 3–6 months to return to normal. Levels of ALT may also be markedly elevated as a result of exposure to drugs or other substances that are toxic to the liver as well as in conditions that cause decreased blood flow (ischemia) to the liver.
ALT levels are usually not as high in chronic hepatitis, often less than 4 times the highest normal level. In this case, ALT levels often vary between normal and slightly increased, so doctors typically will order the test frequently to see if there is a pattern. Other causes of moderate increases in ALT include obstruction of bile ducts, cirrhosis (usually the result of chronic hepatitis or bile duct obstruction), and with tumors in the liver.
In most types of liver diseases, the ALT level is higher than AST, and the AST/ALT ratio will be low. There are a few exceptions. The AST/ALT ratio is usually increased in alcoholic hepatitis, cirrhosis, and with muscle injury.
ALT is often performed together with a test for AST or as part of a liver panel. For more about ALT results in relation to other liver tests, see the Liver Panel article.
Is there anything else I should know?
A shot or injection of medicine into the muscle tissue, or strenuous exercise, may increase ALT levels.
Many drugs may raise ALT levels by causing liver damage in a very small percentage of patients taking the drug. This is true of both prescription drugs and some "natural" health products. Be sure to tell your doctor about all the drugs and health supplements you are taking. Eating too much fast food can also cause mild increases in ALT by causing liver damage; this typically will return to normal when a normal diet is resumed.
Any idea why taking a ph makes us sore all over again? On my day 2 I did a normal workout considering it was only day 2 yet that body part is feeling sore on day 3-4. Not complaining, instead I like it, but does anyone know why? Sorry epstaneman I didn't mean to hijack ur thread but there's a lot of knowledgeable members in here including your self
Picking up a 180 ct bottle tomm thanks. Follow the bottle dosing?
Would you run liv 52 if you ram epi again? Bro you gots me all kinds of worried about my upcoming run
epstaneman said:All kinds of worried? What do you think methylated compounds are? They're designed to BEAT UP the liver and resist break down. Damage is to be expected and if I ran Epi again, which I plan too, I will be using liv52 and probably one other product like tudca on top of it. I'd shoot for a full 4 week run at 45mg ED and eat my ass off.
me too, you got some amazing results bro , especially in just 3 weeks! please keep us updated (also with pics would be awesome) throughout and after your pct
Epstane man, I can't wait to see your post pct results and bloods
Good to hear that things are [mostly] going well.
When you hit the epistane again, you mentioned using the same 45mg dosing. You also planning to stick with the same brand then?
Yeah good to hear so far man,
My AST=33 ALT=28, up from 22/22 btw. This is at week 5 of 6 after switching from EPI to DMZ.
Taking TUDCA however-wont ever run without it probably.
Curious why yours skyrocketed, seems strange.