best nutrient part without na-r-ala

WARBIRDWS6 said:
thats the "combination" I was talking about :D (also slinsane and Na-Rala to be fair).......

Please elaborate
 
WARBIRDWS6 said:
I was saying earlier that when using the right combinations of these type products, they are very effective....you mentioned the duo I was using....

Excellent.
If na r ala was more cost effective I would use it
 
Excellent.
If na r ala was more cost effective I would use it

If you get the 25gram container at NP, its not that bad....since you only use 300mg per day or maybe 450mg on a super carb/calorie day...its lasts quite a while....I really feel its more effective than the other ALA's....
 
AaronJP1 said:
Thx for the support. I'm sure every1 is trying to save money.

I do know where SLINshot can be had for $13 though. ;)

Me too brother, wonder why? Lol
 
Please...list 10 supplements that are more worthwhile than Na-R-ALA.

I eat Na-R-ALA like skittles but let's not pretend we're taking it for nutrient partitioning, you'd say that yourself. That's just a good ingredient that happens to be in nutrient partitioning products
 
I eat Na-R-ALA like skittles but let's not pretend we're taking it for nutrient partitioning, you'd say that yourself. That's just a good ingredient that happens to be in nutrient partitioning products

Nutrient partitioning may not be real, but I consider it synonymous with improved insulin sensitivity, as all the forum bros use the two terms interchangeably.
 
sidoious said:
Me too brother, wonder why? Lol

Cause youre a good man. ;)
 
these things are creating some sort of environment that is conducive to burning fat, sparing muscle, causing pumps etc (talking GDAs ALA AI's)....whether its "repartitioning" or any other term you like to use....its creating the desired effect.....whether by decreasing estrogen, burning fat, decreasing cortisol, impacting insulin sensitivity etc they are working.
 
Nutrient partitioning may not be real, but I consider it synonymous with improved insulin sensitivity, as all the forum bros use the two terms interchangeably.

Is there no product that only activates GLUT-4 in muscles or priorities delivery of nutrients to muscles. I thought AP did this...no?
 
saggy321 said:
Is there no product that only activates GLUT-4 in muscles or priorities delivery of nutrients to muscles. I thought AP did this...no?

Yes anabolic pump.

High % of corosolic acid

Other GDAs or anything that prevents a rise in blood glucose and disposes of glucose away from fat will help you lose fat and prevent glucose tolerance and diabetes.

I use them for cheat meals while cutting.

AP I enjoy all year round. Bulking cutting recomp

Or you can just limit your carb intake.
 
People seem to really dig Anabolic Pump. :D
 
Yes anabolic pump.

High % of corosolic acid

Other GDAs or anything that prevents a rise in blood glucose and disposes of glucose away from fat will help you lose fat and prevent glucose tolerance and diabetes.

I use them for cheat meals while cutting.

AP I enjoy all year round. Bulking cutting recomp

Or you can just limit your carb intake.

That's what I use and have been doing for a month, hence my question. So shouldn't AP be considered a nutrient partitioner in the true sense because it selectively partitions nutrients.
 
saggy321 said:
That's what I use and have been doing for a month, hence my question. So shouldn't AP be considered a nutrient partitioner in the true sense because it selectively partitions nutrients.

None of them are really " selective to muscle tissue" they just repress genes associated with increased adipose mass while enhancing insulin sensitivity in peripheral tissues.

You can say the same about recompadrol and products alike that modulate the PPARy nuclear receptor.

I have been doing some research and from what I have seen I know of 1 ingredient thy is selective. And I will be using it In the near future as a new mimetic product
 
None of them are really " selective to muscle tissue" they just repress genes associated with increased adipose mass while enhancing insulin sensitivity in peripheral tissues.

You can say the same about recompadrol and products alike that modulate the PPARy nuclear receptor.

I have been doing some research and from what I have seen I know of 1 ingredient thy is selective. And I will be using it In the near future as a new mimetic product

Oh snap!
 
None of them are really " selective to muscle tissue" they just repress genes associated with increased adipose mass while enhancing insulin sensitivity in peripheral tissues.

You can say the same about recompadrol and products alike that modulate the PPARy nuclear receptor.

I have been doing some research and from what I have seen I know of 1 ingredient thy is selective. And I will be using it In the near future as a new mimetic product

OK.....so I'm understanding this correctly. AP and others don't activate GLUT-4 in muscles only thereby preferentially funneling nutrients to specific tissues, but rather they repress fat accretion.
 
Speaking of this, I went into my local sup shop just now (I'm on my iPhone) picked up some AP just looking @ it, saw it was expired... (expires Apr 2012) he was like I'll just give it to you (for super cheap)... Don't know what to do with it...
 
saggy321 said:
OK.....so I'm understanding this correctly. AP and others don't activate GLUT-4 in muscles only thereby preferentially funneling nutrients to specific tissues, but rather they repress fat accretion.

In a nutshell yes.

Glut 4 is in muscle and adipose tissue. Just to be clear.
 
AaronJP1 said:
Speaking of this, I went into my local sup shop just now (I'm on my iPhone) picked up some AP just looking @ it, saw it was expired... (expires Apr 2012) he was like I'll just give it to you (for super cheap)... Don't know what to do with it...

Use 4-6 caps a day. Way back when that's when I had best results with it
 
AaronJP1 said:
Speaking of this, I went into my local sup shop just now (I'm on my iPhone) picked up some AP just looking @ it, saw it was expired... (expires Apr 2012) he was like I'll just give it to you (for super cheap)... Don't know what to do with it...

I hear this happening all the time (finding ridiculous deals on clearance or expired items) but its never happened to me... where did you go?
 
uvawahoowa said:
I hear this happening all the time (finding ridiculous deals on clearance or expired items) but its never happened to me... where did you go?

PM me I'll tell u...
 
uvawahoowa said:
I hear this happening all the time (finding ridiculous deals on clearance or expired items) but its never happened to me... where did you go?

Vitamin shoppe usually has a clearance section.

Alternatively you can look at all bottles they have and check expiration dates and fine the one that's going to expire. This way you just tell them it's going to expire and see if they can reduce the price
 
EBF Inc said:
Vitamin shoppe usually has a clearance section.

Alternatively you can look at all bottles they have and check expiration dates and fine the one that's going to expire. This way you just tell them it's going to expire and see if they can reduce the price

Good strategy...will give it a shot next time I'm out there
 
uvawahoowa said:
Good strategy...will give it a shot next time I'm out there

My bottle was a deal I could not pass up. My run it not sure yet as I didn't go in there looking for AP.
 
Royd The Noyd said:
It's predominantly expressed in muscle (something like 90%).

And I'd assume your body fat levels in general would play a role.

Do you have a journal to show that. I've yet to see that ratio. It would be quite interesting
 
Do you have a journal to show that. I've yet to see that ratio. It would be quite interesting

Current understanding of increased insulin sensitivity after exercise - emerging candidates.

Maarbjerg SJ, et al. Show all

Acta Physiol (Oxf). 2011 Jul;202(3):323-35. doi: 10.1111/j.1748-1716.2011.02267.x. Epub 2011 Apr 19.

Molecular Physiology Group, Department of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark.

Abstract Exercise counteracts insulin resistance and improves glucose homeostasis in many ways. Apart from increasing muscle glucose uptake quickly, exercise also clearly increases muscle insulin sensitivity in the post-exercise period. This review will focus on the mechanisms responsible for this increased insulin sensitivity. It is believed that increased sarcolemmal content of the glucose transporter GLUT4 can explain the phenomenon to some extent. Surprisingly no improvement in the proximal insulin signalling pathway is observed at the level of the insulin receptor, IRS1, PI3K or Akt. Recently more distal signalling component in the insulin signalling pathway such as aPKC, Rac1, TBC1D4 and TBC1D1 have been described. These are all affected by both insulin and exercise which means that they are likely converging points in promoting GLUT4 translocation and therefore possible candidates for regulating insulin sensitivity after exercise. Whereas TBC1D1 does not appear to regulate insulin sensitivity after exercise, correlative evidence in contrast suggests TBC1D4 to be a relevant candidate. Little is known about aPKC and Rac1 in relation to insulin sensitivity after exercise. Besides mechanisms involved in signalling to GLUT4 translocation, factors influencing the trans-sarcolemmal glucose concentration gradient might also be important. With regard to the interstitial glucose concentration microvascular perfusion is particular relevant as correlative evidence supports a connection between insulin sensitivity and microvascular perfusion. Thus, there are new candidates at several levels which collectively might explain the phenomenon.
 
i see where your going with this. but this is in exercised individuals. The expression of Glut4 is in high aboundance in muscle and fat.

Exercise is truely specific to muscle tissue because muscle contraction increases Glut4 expression and translocation in muscle cells.
 
I think our discussion is centered around exercise independent effects of GDAs upon nutrient uptake. That would be the real test of a GDA....whether it alone can funnel nutrients to specific tissue.
 
what was being discussed was muscle specificity of the products in regards to glucose uptake. The post workout window is not included in this.
 
what was being discussed was muscle specificity of the products in regards to glucose uptake. The post workout window is not included in this.

Yes, but you are trying to achieve the same action one would get from exercise. You're essentially talking about the benefits of exercise without exercising...
 
The muscle facilitative
glucose transporter isoform 4 (GLUT4) translocation from low-density microsomal membrane to plasma membrane
was significantly increased in the orally CA-treated mice when compared with that of the controls
(p0.05). These results suggest that the hypoglycemic effect of CA is derived, at least in part, from an increase in
GLUT4 translocation in muscle.

Invalid Link Removed
 
I want to be the rep for Na-Rala......who do I talk to? NP people? Maybe I will rep some GDA's too, not sure. But definitely want to rep Na-Rala. Not just to get some free either, although I want some for free.
 
WARBIRDWS6 said:
I want to be the rep for Na-Rala......who do I talk to? NP people? Maybe I will rep some GDA's too, not sure. But definitely want to rep Na-Rala. Not just to get some free either, although I want some for free.

Lol. What?
 
mr.cooper69 said:
In summary, exercise is the best nutrient partitioner you can find

Per the title of this thread. But is exercise a supplement. :P
 
so exercise is the the best nutrient partitioner and diet is the best supplement? Why do we have these damn supplement and anabolic sections? SHUT THEM DOWN! training and diet/nutrition forums are the only ones we need :D

("partitioner" got a red squiggly line, apparently this is NOT a word)
 
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