TheDarkHalf said:
Yeah man I'd roll with mdrol/epi with transaderm....would provide some nice gains if your diet is right
What exactly are you trying to prove with this study?
If you actually read it throughout you'll find it only validates my concerns.
You probably only read to the second page and checked out the charts.... That's only the first 6 days.
Continue on to page 3 where they continue to discuss the results of blood tests 5 weeks out (after only 6 days of use they tested then again 5weeks out to see if things "normalize") and although test was increased 50% estrogen was increased 3 fold or in other words 300%.
This coupled with the fact dhea can have a direct interaction with the ER without ANY conversion and this was only a 6 day supplementation routine (not 4-8 weeks like oral ph cycles) I'd be worried considerably about estrogen related side effects from topical dhea supplementation.
This also means even 5 weeks after cessation, after pct, your still going to have the downstream cascade of hormone conversions to estrogen and the like, likely at an even higher rate then in the study cause of compounded use beyond that of the 6 days of supplementation in the study.
4-dhea and 1-dhea do not suffer from these problems as they either can't aromatize directly to estrogen or have to reach the target hormone, testosterone, to even be effected (1-test can't aromatize).
Supplementation with 4-dhea would be a valid and wiser option during a cycle, but unless your WANTING estrogen increases, I wouldn't touch dhea without an AI.... Even then the metabolite 5-androstenediol can directly interact with the ER and effects dhea can have on the thyroid should be considered before use...
So, again, what was the point of posting that study? Cause only a link tells me nothing regarding what you were trying to prove.