Blew my knee out when I was 19 (am 22 now), and have periodic pain in both knees. Left knee has a surgically repaired medial meniscus and ACL (Torn meniscus, grade 2 shredding on ACL). Right knee pains from overcompensation over the last couple years. Super-Cissus completely eliminated any pain I had. Fantastic product. I did not take Glucosamine/Chondroiton/MSM either, just the SCRx. When I can afford another bottle I'll be purchasing as the pains have been slowly coming back. Well done guys. Great product.