Toxicity of liquid orals vs. tabs/pills
- Thread starter boggs67ss
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boggs67ss
Member
I figured since the structure is still the same, just seems less harsh since liquid gets disolved under your tongue, where as a tab is physically broken down inside.
UnrealMachine
Well-known member
Easy is right, 50mg of compound X is the same toxicity whether its solid in a pill or in solution. The only difference is pills have binders holding the solid compound together into a shape, and liquids have solvents holding the compound in solution.
Boggs, liquid orals are ORAL, you drink them... When you say under your tongue that's sublingual, that's a different delivery system, and that would not negate the harshness of oral steroids! I don't know what solvent they're in but if they're like research chems, they taste far too horrible for the sublingual method anyway
Boggs, liquid orals are ORAL, you drink them... When you say under your tongue that's sublingual, that's a different delivery system, and that would not negate the harshness of oral steroids! I don't know what solvent they're in but if they're like research chems, they taste far too horrible for the sublingual method anyway
EasyEJL
Never enough
generally the liquid ones are in PEG 300 or 400, sometimes with alcohol added.
Sublingual is different, but in the end not that different sadly. What sublingual does for some compounds is make them more bioavailable. But 17a steriods are already as bioavailable as they can be so making them sublingual doesn't do much. Now taking something like 1-T or 1AD or even Testosterone without an ester and making it sublingual will make it a lot more available than orally
Sublingual is different, but in the end not that different sadly. What sublingual does for some compounds is make them more bioavailable. But 17a steriods are already as bioavailable as they can be so making them sublingual doesn't do much. Now taking something like 1-T or 1AD or even Testosterone without an ester and making it sublingual will make it a lot more available than orally
EasyEJL
Never enough
It shouldn't make a huge difference either way.
For true sublinguals they are made with cyclodextrin, a compound that has a similar molecular shape to flattened buckyballs
this is what they look like Invalid Link Removed
so the idea is that the chemical you want to deliver ends up with a molecule of it going into the donut hole of the cyclodextrin, and the cyclodextrin transports it across the lining of the mouth and then falls apart leaving the active molecule to roam free in your bloodstream.
For true sublinguals they are made with cyclodextrin, a compound that has a similar molecular shape to flattened buckyballs
this is what they look like Invalid Link Removedso the idea is that the chemical you want to deliver ends up with a molecule of it going into the donut hole of the cyclodextrin, and the cyclodextrin transports it across the lining of the mouth and then falls apart leaving the active molecule to roam free in your bloodstream.
texastweeter
Active member
I have heard of sublinguals being sprayed up the nasal cavity too. heard it was pretty harsh on the lining though. I read somewhere that liquid win bound better when it was taken orally than when it was pinned...but f course that never stopped me from pinning it. someone correct me if Im wrong.