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Resveratrol bioavailibility, bad or maybe not?

These guys (purists) would recommend Nutra's resV (99% purity) over Stoked (50% purity). Not sure why - but they've the experience.
 
matthias7 said:
These guys (purists) would recommend Nutra's resV (99% purity) over Stoked (50% purity). Not sure why - but they've the experience.
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True, especially if you want to reduce any conflicts for absorption.
 
yeah what about the reservatrol in sustain alpha?

but i think the benzoflavone is the main ingrediant
 
Purity is pretty important in my experience, low emodin content, and micronization are the other factors affecting absorbtion and bioavailability. I have had best results and less sides with this type of oral product. Some people cant tolerate Resveratrol in any form.
 
Maybe if you apply Sustain Alfa on the scrotum which a lot of people do, including me ;)

I just read a study TD test is absorbed 40 times better through the scrotal skin then on the chest/shoulders/abs. 2nd best site is cheeks.

Still I think the most effective part of SA is the 7,8 benzoflavone.

Trisorbagen (bioperine) would only take care of the glucuronication part which as in my first post might not be a good thing to inhibit.

Therefore, it is likely that at least a portion of resveratrol is unzipped from its protective carrier by the glucuronidase enzyme and could be converted back to free resveratrol. Since tissue or serum beta-glucuronidase enzyme activity is elevated in certain diseased tissues, such as cancer, liver diseases, and AIDS, resveratrol would be targeted and released more so in these tissues than in healthy ones. Researchers state that “these observations… raise the possibility that glucuronidation of resveratrol may have a role in detoxification, disposition, and prolongation of the effectiveness of resveratrol in humans.”
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Quercetin (like in stoked) takes care of the sulfanation in the liver. I would be enclined to go that route before targeting resv glucuronication..
 
I use alot of supplements. ALOT.

I'm not really impressed by much these days.

But Primordial, and specifically Sustain Alpha, gets the RR thumbs up, for sure.

They really surprised me with that product.
 
RenegadeRows said:
agreed. other products with resveratrol didnt get me like SA did. the combo of the two is killer.
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Well I'm not so convinced about the resveratrol in SA producing any results. I like SA very much myself, its actually really working and a great product, but I suspect the benzoflavone is doing all of that ;)
 
i was planning on running an act X and stoked stack but now im thinking i might drop the stoked and get glycobol instead. do you think getting NOW resveratrol would be a good addition in place of the stoked?
 
As of yesterday I added Quercetin, Curcumin, IP6 and bioperine (AX Trisorbagen) to my morning 500mg 99% Resveratrol serving (empty stomach and atleast 2 hours before taking in food). Will report back if I notice a difference or not.
 
My Achilles heal tendinitis has finally gone away after reducing my intake from once a day to once a week. Took about 6 weeks to disappear. Sleep has improved too.
 
edvanp said:
My Achilles heal tendinitis has finally gone away after reducing my intake from once a day to once a week. Took about 6 weeks to disappear. Sleep has improved too.
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Did you try increasing your copper intake? Do you supplement with zinc? Both Resv and zinc have been reported to deplete copper which can cause your "tendinitis". So they say anyway ;)
 
Often thats a transient side> What kind of RSV are you taking? It could be from a compounded, low purity, high emodin content, non-micronized type, after I switched to pure, I had no problems.
 
I was taking Anabolic Innovations Post Cycle Support. I did read that Copper can be depleted, causing the tendinitis. I decided to back it off to once a week and the symptoms finally disappeared.
 
Yeah high zinc will deplete copper, without copper being around. ZMA should contain copper to maintain the zinc IMO. Then again since I've never taken it (and never will) I can't comment.

resV deplete copper is a bit worrying. Just started mine BTW using Nutra's for the time being.
 
matthias7 said:
Yeah high zinc will deplete copper, without copper being around. ZMA should contain copper to maintain the zinc IMO. Then again since I've never taken it (and never will) I can't comment.

resV deplete copper is a bit worrying. Just started mine BTW using Nutra's for the time being.
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I'm taking MST ZMK and eat nuts every day.. I get enough copper in ;)
 
I also eat a lot of nuts and I try to sneak in some dark chocolate too, which apparently is also a good source of copper. Like most supplements, they likely have different effects on each individual. I'm just glad I figured it out!
 
i heard that taking resv with wine is great cause ethanol seems to aid with the absorption ,and it makes sense since red wine was one of the first talked efficient resv foods out there
 
I think that taking a pure, micronized, emulsified RSV is the way to go, anything else seems to give sides, for me anyway. Other people dont seem to have any problems with less than pure, compounded, non-micronized supps.
 
Feedback Ive read is positive, I prefer my RSV to be straight though. Anyone shut-down is bound to benefit from RSV in probably any form.
 
edvanp said:
I also eat a lot of nuts and I try to sneak in some dark chocolate too, which apparently is also a good source of copper. Like most supplements, they likely have different effects on each individual. I'm just glad I figured it out!
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Calf's liver and sesame seeds are also excellent sources if you're low in copper ;)
 
matthias7 said:
What sort of nuts ? Brazil, almond and walnuts were what I was recommended.

All nuts are equal, but some nuts are more equal than others...
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I take 100 grams walnuts, almonds, cashews mainly 2:1:1 with 6 grams of fishoil. My O3 : O6 is 1:4 then on average. Sometimes I exchange some nuts, take some hazelnuts/macadamia's etc.. Walnuts have 1 : 4 O3 : O6 by themselves..
 
Ohh .... do you precisely regulate your O3 to O6 in your total diet? Wow that is a precise diet if so. Really precise.

Also why cashews - that is news to me? I wasn't aware there was anything special in them. Well thats what I was told. Also would you grind your walnut/etc.... ratio to maximize the absorption? (I was going to write do you grind your nuts - but I thought given the hijacks on this thread - it wasn't a good idea)
 
matthias7 said:
Ohh .... do you precisely regulate your O3 to O6 in your total diet? Wow that is a precise diet if so. Really precise.

Also why cashews - that is news to me? I wasn't aware there was anything special in them. Well thats what I was told. Also would you grind your walnut/etc.... ratio to maximize the absorption? (I was going to write do you grind your nuts - but I thought given the hijacks on this thread - it wasn't a good idea)
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Yeah I do indeed.

Nothing especially special about cashews but I like their taste, walnuts and almonds are probably a better choice on a 1 to 1 basis ;)

I input all I take in Invalid Link Removed and try to balance mineral and omega intake. I also take MST ZMK for mineral content.

It just works out right for me when I take these nuts in these ratio's with added fish oil.

BTW I only eat nuts and use ZMK 5 days a week. On weekends I lower my mineral intake. I also do some minreal chelating, take IP6, resveratrol, vitmain D3/K2 etc to remove excess minerals as this should theoratically aid in longetivity.
 
to remove excess minerals as this should theoratically aid in longetivity.
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Wow never heard that, do you have a source or could you explain a bit more about that?
BTW which multi do you use 1HP? (sorry for the off topic question)
 
E J said:
Wow never heard that, do you have a source or could you explain a bit more about that?
BTW which multi do you use 1HP? (sorry for the off topic question)
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There's a lot of information on that subject on imminst.org.

A short summary of things that spring to mind on that subject:

Excess calcium hardens/clogs up the arteries.
Excess Iron oxidizes (rusts) and does damage to cell membrames, organs like the liver etc.

Do a search on Iron chelation, heavy metal chelation and calcium chelation on imminst.org or google, loads of information there.

IP6 for metal chelation. D3/K2 for calcium chelation.

Ofcourse there's always a catch, if you remove too much iron/calcium from your body you run into trouble aswell ;)
 
E J said:
Wow never heard that, do you have a source or could you explain a bit more about that?
BTW which multi do you use 1HP? (sorry for the off topic question)
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Found a nice link for you explaining it all:

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Scroll down to the bit about Iron overload and calcification.
 
1HP said:
Yeah I do indeed......
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Well I expect to see you posting on here for the next 100 years or so ;)
The sources of copper are good to know; I should have been told this 'cause I pay to have someone tell me this stuff and I've raised this issue with them before. Actually scrub that by implication ... well you know ... I owe you money! :nervous:

1HP said:
I also do some minreal chelating, take IP6, resveratrol, vitmain D3/K2 etc to remove excess minerals as this should theoratically aid in longetivity.
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Do you do mineral hair analysis? The idea is that the true mineral composition of your body is locked in your hair. Plus all the pollution stuff. I was going to do this but haven't yet got around to having my hair cut. Its reasonably priced, cheaper than saliva hormone screens.

IP6.. I dunno what this is.
 
IP6.. I dunno what this is.
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I didn't know what this is either, after a quick search I found that it is also known as Inositol Hexaphosphate, it chelates heavy metals, and impedes their oxidation.

Please correct me if I'm wrong 1HP
 
matthias7 said:
Well I expect to see you posting on here for the next 100 years or so ;)
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Hmm I wonder ;) I'm also doing/have done some less good things to myself, I enjoy life too much sometimes, I hope to atleast make it to a decent age in decent health ;)

matthias7 said:
Do you do mineral hair analysis? The idea is that the true mineral composition of your body is locked in your hair. Plus all the pollution stuff. I was going to do this but haven't yet got around to having my hair cut. Its reasonably priced, cheaper than saliva hormone screens.

IP6.. I dunno what this is.
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No but it sounds interesting, I'm planning on running all of this for ~3 months and then get a complete checkup, bloodwork for everything etc. This sounds like a good addition. Then adjust from there.

E J said:
I didn't know what this is either, after a quick search I found that it is also known as Inositol Hexaphosphate, it chelates heavy metals, and impedes their oxidation.

Please correct me if I'm wrong 1HP
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Thats 100% correct :) I take it mainly for Iron chelating. I also take in a decent amount of Iron from nuts/cacao beans/goji berries so I dont think I will have low iron issues. But I'll get it checked in a few months to be on the safe side.

If you're thinking on taking IP6 remember to not take it with any minerals since it will bind to them..
 
Found this too:

"Iron can also be removed by intravenous EDTA chelation therapy, or more conveniently and economically by the use of IP6 rice bran extract, available at health food stores or online (brands: Jarrow, Source Naturals, Purity Products). The consumption of IP6 rice bran extract on an empty stomach with water will chelate (remove) excess iron and other heavy metals from the liver, kidneys, gallbladder, brain, heart and other organs. IP6 does not remove iron from red blood cells. If IP6 is used excessively for long periods of time it could induce anemia, which would cause symptoms of fatigue, paleness, craving of acidic foods (tomatoes) and cold hands and feet."
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There are MD's that specialize in this chelation therapy, one of the foremost in located in a small ohio town. Its alternative medicine but if the person is an MD it might be worth a try. IP6 doesnt seem to agree with me, its a part of a popular RSV product that I quit taking, the straight emulsified RSV seems to be better for my system. JMO
 
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