Strong P-slin Alternative?

[dertynasty]

A pretty smart guy over on another bb'ing forum was making custom capsule creations and i found this post of his to be quite interesting. I feel that since i don't respond to AP or yellow gold, i need a new food transporting supplement to take its place and this formula looked quite beneficial. It has ingredients in p-slin as well as a bunch of other synergistic things that provide efficient regulation of blood sugar levels. I was going to make this capsule so tell me what you guys think.

"The Dream Custom Capsule:
InsuDream, Anabolic Insulin, Glucocell, InsuFlex, Hyper-slin are a few names I just came up with. With custom capsule, you can name your own product.

Take 5 capsules ideally with breakfast and another 5 post-workout or with largest meal of the day.
Or take 3 before every meal and 3-4 post-workout.
Food may reduce absorption of Na-RLA so it can be taken around 30mins before meals if low-blood sugar problems are not an issue.

Aim for 10-12 caps/day.

Pills Per Serving: 10
Servings Per Batch: 30
Pills Per Batch: 300

Ingredients:

Banaba Leaf PE 1% 500 MG
Biotin 2000 MCG 667%
Bitter Melon Ext. 300 MG
Chromium 200 MCG 167%
Cinnamon Bark Extract 900mg
Na R-Alpha Lipoic Acid 250mg
Naringin 25 MG
Resveratrol 70 MG
Green Tea Extract 400 MG
Magnesium 200 MG 50%
Vitamin C 100 MG 167%
Vitamin D3 500 IU 125%
Quercetin 590 MG

Total:44.04

If you go with more batches you get a better deal and they now offer an awesome 20% off until the end of this month.

Believe me, every nutrient has a reason for being included, some are very syngergistic with others like the biotin/chromium, Quercetin/Resveratrol and the naringin offers a powerful uptake mechanism for nutrient absorption. Bioperine would be nice but naringin has been reported to work well.
There was even a product formulated for blood sugar control based on the studies showing synergism of high dose biotin and chromium. Just two ingredients I have in my custom cap.

Magnesium is a commonly deficient nutrient in western society and offers powerful benefits in insulin resistence situations. The aspartate form is highly bioavailable and in elemental form so 200mg/day would go a long way for most people and a nice amount for those also not deficient.

Vitamin D and its benefits to insulin function is a growing area of research. It is not hard to find studies showing both deficiencies and the negative results on blood sugar and insulin resistance. D3 is the form you want and CC offers this. I think 500iu is a nice level for anyone and would go well with those getting between 400-1000iu from their multi's and other supps. Many are now recommending aiming for at least 1000iu and up to 5000iu with no worries of overdose. Many think 2000iu is the sweet spot here. The benefits of this amazing vitamin a too numerous to mention, but I'm sure many here have been hearing more about this vitamin."

 

[Tkenshin]

wow this is interesting, how was his feed back on this, looks like it could get expensive.

 

[EasyEJL]

not bad, i would drop the resveratrol + quercetin tho. its not enough resveratrol to matter, and the quercetin without enough offsetting resveratrol can cause libido issues over time. plus that would drop the caps to more like 6-7 per serving I think. I've taken the resveratrol/quercetin combo to as high as 2g/1.6g which is awesome, but less than 500mg of resveratrol has virtually no effect other than placebo.

 

[strategicmove]

...
Aim for 10-12 caps/day.

Pills Per Serving: 10
Servings Per Batch: 30
Pills Per Batch: 300

Ingredients:

Banaba Leaf PE 1% 500 MG
Biotin 2000 MCG 667%
Bitter Melon Ext. 300 MG
Chromium 200 MCG 167%
Cinnamon Bark Extract 900mg
Na R-Alpha Lipoic Acid 250mg
Naringin 25 MG
Resveratrol 70 MG
Green Tea Extract 400 MG
Magnesium 200 MG 50%
Vitamin C 100 MG 167%
Vitamin D3 500 IU 125%
Quercetin 590 MG

Total:44.04

If you go with more batches you get a better deal and they now offer an awesome 20% off until the end of this month.

Believe me, every nutrient has a reason for being included, some are very syngergistic with others like the biotin/chromium, Quercetin/Resveratrol and the naringin offers a powerful uptake mechanism for nutrient absorption. Bioperine would be nice but naringin has been reported to work well.
There was even a product formulated for blood sugar control based on the studies showing synergism of high dose biotin and chromium. Just two ingredients I have in my custom cap.

Magnesium is a commonly deficient nutrient in western society and offers powerful benefits in insulin resistence situations. The aspartate form is highly bioavailable and in elemental form so 200mg/day would go a long way for most people and a nice amount for those also not deficient.

Vitamin D and its benefits to insulin function is a growing area of research. It is not hard to find studies showing both deficiencies and the negative results on blood sugar and insulin resistance. D3 is the form you want and CC offers this. I think 500iu is a nice level for anyone and would go well with those getting between 400-1000iu from their multi's and other supps. Many are now recommending aiming for at least 1000iu and up to 5000iu with no worries of overdose. Many think 2000iu is the sweet spot here. The benefits of this amazing vitamin a too numerous to mention, but I'm sure many here have been hearing more about this vitamin."[/I]

Altogether a good blend. First of all, I would tend to agree with Easy. If you cannot get Resveratrol (read "Trans-Resveratrol") to at least 200mg daily, you might not get the desired benefits.

Quercetin has many nice benefits of its own, apart from ensuring better trans-resveratrol bioavailability. The more trans-resveratrol you have in your blend, the better the overall resveratrol-quercetin synergy.

Apart from cAMP elevation and related benefits, Naringin has desirable property of improving the bioavailability of many other compounds and extending their half-lives. (Because Naringin is non-discriminating in this area, it can also potentiate the sides from some compounds). Yet, I miss Bioperine, the classic nutrient and supplement delivery compound. Given the complexity of the blend you have, 5mg of Bioperine per dose may help.

The amount of vitamin C in your blend is low. I would drop it entirely and supplement it stand-alone at about 1 000mg per dose.

I suppose the amount of Green Tea Extract of 400mg refers to Green Tea's main polyphenol and catechin, epigallocatechin gallate (EGCG). If you are not supplementing Green Tea Extract from anywhere else, you might want to consider a daily EGCG dose of at least 500mg.

Be sure of how much magnesium you are getting from other sources (multivitamin/mineral products, ZMA-type products, ZMK, and so on). If you are taking these, you may not need additional magnesium in your blend.

Vitamin D3 has many useful benefits. Yet, it is easy to forget is is a hormone (cholecalciferol), and the intake should be watched. Furthermore, only sedentary individuals (or those in cold areas of Europe close to the North Pole) that lack exposure to sunlight are at a risk of D3 deficiency. If you get about 15 minutes exposure to the sun daily, you should not need more than 1 000IU daily (from all sources).

Something else I miss is Gymnema Sylvestre. This is one of the best compounds for insulin synthesis. It should be in a blend like yours.

 

[CROWLER]

I agree on the Resveratrol, just not enough to do much if any good.


CROWLER

 

[jmh80]

Something else I miss is Gymnema Sylvestre. This is one of the best compounds for insulin synthesis. It should be in a blend like yours.

Agree. CustomCap may not have gymnema though.

I do like that supp. I used to stock up at Vitamin World on their brand of it - till the store shut-down.

 

[strategicmove]

Agree...

I do like that supp. I used to stock up at Vitamin World on their brand of it - till the store shut-down.

You probably know NutraPlanet stocks the same thing from NOW Foods: Invalid Link Removed

 

[jmh80]

I found a bottle of it cheaper off Ebay.

Am going to be out soon though. I'll get some at NP.

 

[EasyEJL]

The amount of vitamin C in your blend is low. I would drop it entirely and supplement it stand-alone at about 1 000mg per dose.

Actually the 100mg is ok if you take these caps 1 at at time, like 90 min apart. 1000mg at once of c is only useful if its time released. the body doesn't use much more than 50-60mg/hr, and half life in plasma is about 60 min as well.

I worked for hoffman la roche in the 80s in their vitamin product R&D lab, and recall the studies done. we were formulating the sunkist vitamin c chewables that came in the lifesaver type rolls. I got to try all sorts of flavors that never hit the market

 

[strategicmove]

Actually the 100mg is ok if you take these caps 1 at at time, like 90 min apart. 1000mg at once of c is only useful if its time released. the body doesn't use much more than 50-60mg/hr, and half life in plasma is about 60 min as well...

Yes, you would probably agree that the advantage of the time-release concept is to ensure stable cellular concentrations of vitamin C, as it is water-soluble. So, either you use the time-release technology, or you dose vitamin c several times daily, preferably with cofactors such as citrus flavonoids, and the potent vitamin-c recharger, dihydroquercetin. I take about 5 000mg of vitamin c daily, in about 5 doses

 

[dertynasty]

Good imput guys. I agree with you when you say that some of the doses are too low, however the products main function should be coming from the Na-r-ala as well as the bitter melon, cinnamon extract, and banaba leaf extract.
My original formulation was just going to have these compounds in it alone at much higher doses for the use of strictly nutrient partitioning before a meal. However, after reading this guys post, It seemed like like there could be much of an upgrade to it, so i figured i would guy your guys' opinions on it.

If you WERE to remake this pill strictly for the purposes AP/ Pslin has on food, how would you do it exactly?

 

[Guest]

A pretty smart guy over on another bb'ing forum was making custom capsule creations and i found this post of his to be quite interesting. I feel that since i don't respond to AP or yellow gold, i need a new food transporting supplement to take its place and this formula looked quite beneficial. It has ingredients in p-slin as well as a bunch of other synergistic things that provide efficient regulation of blood sugar levels. I was going to make this capsule so tell me what you guys think.

"The Dream Custom Capsule:
InsuDream, Anabolic Insulin, Glucocell, InsuFlex, Hyper-slin are a few names I just came up with. With custom capsule, you can name your own product.

Take 5 capsules ideally with breakfast and another 5 post-workout or with largest meal of the day.
Or take 3 before every meal and 3-4 post-workout.
Food may reduce absorption of Na-RLA so it can be taken around 30mins before meals if low-blood sugar problems are not an issue.

Aim for 10-12 caps/day.

Pills Per Serving: 10
Servings Per Batch: 30
Pills Per Batch: 300

Ingredients:

Banaba Leaf PE 1% 500 MG
Biotin 2000 MCG 667%
Bitter Melon Ext. 300 MG
Chromium 200 MCG 167%
Cinnamon Bark Extract 900mg
Na R-Alpha Lipoic Acid 250mg
Naringin 25 MG
Resveratrol 70 MG
Green Tea Extract 400 MG
Magnesium 200 MG 50%
Vitamin C 100 MG 167%
Vitamin D3 500 IU 125%
Quercetin 590 MG

Total:44.04

If you go with more batches you get a better deal and they now offer an awesome 20% off until the end of this month.

Believe me, every nutrient has a reason for being included, some are very syngergistic with others like the biotin/chromium, Quercetin/Resveratrol and the naringin offers a powerful uptake mechanism for nutrient absorption. Bioperine would be nice but naringin has been reported to work well.
There was even a product formulated for blood sugar control based on the studies showing synergism of high dose biotin and chromium. Just two ingredients I have in my custom cap.

Magnesium is a commonly deficient nutrient in western society and offers powerful benefits in insulin resistence situations. The aspartate form is highly bioavailable and in elemental form so 200mg/day would go a long way for most people and a nice amount for those also not deficient.

Vitamin D and its benefits to insulin function is a growing area of research. It is not hard to find studies showing both deficiencies and the negative results on blood sugar and insulin resistance. D3 is the form you want and CC offers this. I think 500iu is a nice level for anyone and would go well with those getting between 400-1000iu from their multi's and other supps. Many are now recommending aiming for at least 1000iu and up to 5000iu with no worries of overdose. Many think 2000iu is the sweet spot here. The benefits of this amazing vitamin a too numerous to mention, but I'm sure many here have been hearing more about this vitamin."

This formula will cause extra insulin secretion. Pslin works indepenendent of insulin.

If you are sensitive to fat gain, I would avoid compounds that force insulin secretion.

Quercertin and narginin are not needed. For one, the insulin like compounds do not have absorption issuess and Two, if it did prolong the half life of the formula that would be a bad scenario in this case. You do not want to prolong insulin secretion.