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Applied Nutriceuticals wants a few Neovar Logs

johnyq said:
:lol:

I was about to mention I might pick up a corgi soon, but it sounds like even that would swallow your dogs. Small dogs are cool though, I grew up with lasso apsos, no idea how I ended up with big dogs.


anyways, thanks for considering me :afro:
Click to expand...

I grew up with Dobermans.... so I have love on both ends of the spectrum...
 
I've read alot of mixed reviews of CEE on this board.

Here's a link copied that I read:

Creatine Ethyl Ester (CEE)
--------------------------------------------------------------------------------

Here's a mail I recently received from some friends (PhDs) in the Ex Sci/Nut Biochem community. It discusses the potential dangers and (flawed marketing picture) associated with the use of Creatine Ethly Ester:


1) CEE is a true covalently bonded ester and is absorbed into blood and
tissues as the intact molecule. This is the picture that the
manufacturers would have us believe and is the basis for why they claim
CEE is superior to creatine monohydrate. However, inside cells CEE
will be unreactive with creatine kinase and may be a potential
competitive or non-competitive inhibitor to the enzyme. This would
make it toxic to brain, heart, testes, muscle and all other CK
containing tissues. People by now should be dying, but clearly are not
and this means 2) and 3) are the more likely. Nonethess, CEE should be
treated as a potentially toxic phrarmaceutical and in the US should be
treated as a drug, which requires multi species studies
to estimate LD50's and potential sites of tissue damage etc. However, recently I have been told that CEE did get new dietary ingredient status (scary).

2) CEE is hydrolysed to creatine on absorption from the gut. In this
case CEE offers no advantage over creatine monohydrate which has a
bioavilability of 100%. Indeed if hydrolysis of CEE is less than 100%
then it will be inferior to the monohydate. But in the case of
hydrolysis there are no circumstances in which it could be better than
the monohydrate in increasing tissue creatine levels. Obviously CEE
manufacturers would prefer 1) except that they then shoot themselves in
the foot over the issue of potential toxicity.

3) CEE is not a true covalently bonded ester. The whole of this is a scam
with the compound ionising in solution to free creatine, as does the
monohydrate and all salts of creatine. In this case CEE would again
represent no advantage over creatine monohydrate, except to the seller
who can double the price.

The failure of the US sports nutrition community (industry and the
universities) to call for closer examination of CEE seriously questions its
credibility in the eyes of many scientist in this country and the world. A simple water solvation test would answer 3), i.e. whether or not it was a covalent or ionisable derivative of creatine. The work time would be about one hour. Investigation of whether CEE is a competitive or non-competitive inhibitor of creatine kinase would take 2-3 hours. If either of these occured then clearly CEE must be investigated in at least two species to investigate lethality and potential organ damage. If on the other hand CEE is ionisable then I see no reason why a bioavailability study should not be undertaken comparing this, on a molar/molar basis, with
creatine monohydrate. My guess is that plasma AUC would be identical.
Again a very simple study.

None of this is rocket science but could spare a few lives, if the
manufacturers claims on the absorption of CEE are to believed.
Invalid Link Removed


Here's an interesting thread "CEE is Crap"
Invalid Link Removed

Originally found in this thread:

http://anabolicminds.com/forum/supplements/72225-creatine-ethyl-ester.html


The above thread on anabolicminds basically concludes that CEE is junk.

Why is Neovar any better?

I'd like to see someone JUST DO NEOVAR and show results. No PH or PS or Gear or any other natty test. Just NeoVar or some other CEE.
 
edwards said:
I've read alot of mixed reviews of CEE on this board.

Here's a link copied that I read:

Creatine Ethyl Ester (CEE)
--------------------------------------------------------------------------------

Here's a mail I recently received from some friends (PhDs) in the Ex Sci/Nut Biochem community. It discusses the potential dangers and (flawed marketing picture) associated with the use of Creatine Ethly Ester:


1) CEE is a true covalently bonded ester and is absorbed into blood and
tissues as the intact molecule. This is the picture that the
manufacturers would have us believe and is the basis for why they claim
CEE is superior to creatine monohydrate. However, inside cells CEE
will be unreactive with creatine kinase and may be a potential
competitive or non-competitive inhibitor to the enzyme. This would
make it toxic to brain, heart, testes, muscle and all other CK
containing tissues. People by now should be dying, but clearly are not
and this means 2) and 3) are the more likely. Nonethess, CEE should be
treated as a potentially toxic phrarmaceutical and in the US should be
treated as a drug, which requires multi species studies
to estimate LD50's and potential sites of tissue damage etc. However, recently I have been told that CEE did get new dietary ingredient status (scary).

2) CEE is hydrolysed to creatine on absorption from the gut. In this
case CEE offers no advantage over creatine monohydrate which has a
bioavilability of 100%. Indeed if hydrolysis of CEE is less than 100%
then it will be inferior to the monohydate. But in the case of
hydrolysis there are no circumstances in which it could be better than
the monohydrate in increasing tissue creatine levels. Obviously CEE
manufacturers would prefer 1) except that they then shoot themselves in
the foot over the issue of potential toxicity.

3) CEE is not a true covalently bonded ester. The whole of this is a scam
with the compound ionising in solution to free creatine, as does the
monohydrate and all salts of creatine. In this case CEE would again
represent no advantage over creatine monohydrate, except to the seller
who can double the price.

The failure of the US sports nutrition community (industry and the
universities) to call for closer examination of CEE seriously questions its
credibility in the eyes of many scientist in this country and the world. A simple water solvation test would answer 3), i.e. whether or not it was a covalent or ionisable derivative of creatine. The work time would be about one hour. Investigation of whether CEE is a competitive or non-competitive inhibitor of creatine kinase would take 2-3 hours. If either of these occured then clearly CEE must be investigated in at least two species to investigate lethality and potential organ damage. If on the other hand CEE is ionisable then I see no reason why a bioavailability study should not be undertaken comparing this, on a molar/molar basis, with
creatine monohydrate. My guess is that plasma AUC would be identical.
Again a very simple study.

None of this is rocket science but could spare a few lives, if the
manufacturers claims on the absorption of CEE are to believed.
Invalid Link Removed


Here's an interesting thread "CEE is Crap"
Invalid Link Removed

Originally found in this thread:

http://anabolicminds.com/forum/supplements/72225-creatine-ethyl-ester.html


The above thread on anabolicminds basically concludes that CEE is junk.

Why is Neovar any better?

I'd like to see someone JUST DO NEOVAR and show results. No PH or PS or Gear or any other natty test. Just NeoVar or some other CEE.
Click to expand...

That's exactly what I suggested if I was to do a log on the product. This actually applies to any product testing in my opinion. If you are taking multiple products how can you ever know what is doing what.
 
Lanbane said:
bioman and theninja, you guys are in there like swimwear. PM me shipping info. I'll reply to PM's with more in-depth discussion.


Standby list (No guarantees at this point):
imprezivr6
johnyQ
devil

.
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Imprezivr, johnyQ, devil, and distilled water... PM me your shipping info. I'll discuss further with you after this.
 
Nice picks, Lanbane. Looking forward to the logs.
 
Lanbane; said:
Thank you, sir. I think these guys will do a great job of reviewing the product, and I truly hope they enjoy it and see some benefit from it's use. Pretty confident this will be the case. :head:
Click to expand...
No doubt. Keep the ball rolling!
 
Lanbane said:
Imprezivr, johnyQ, devil, and distilled water... PM me your shipping info. I'll discuss further with you after this.
Click to expand...

I'm pretty sure I sent a PM last night, let me know if I didn't. Thanks for the opportunity :cheers:
 
they haven't diminished... I am just jacked up on RPM. Makes me very alert. I sensed displacement of a few air particles when your screen name appeared.
 
Lanbane said:
they haven't diminished... I am just jacked up on RPM. Makes me very alert. I sensed displacement of a few air particles when your screen name appeared.
Click to expand...

lol - add that to the list of RPM benefits. It could be a huge seller among pirates.
 
RPM is what caused the Philidelphia Experiment, if you guys didn't know. It was classified top secret. The crew took the RPM, and vanished into thin air, only to re-appear 40 seconds later out of no where with their bodies and the ship displaced together! Luckily Dirk perfected the formula and now you don't have to worry about that!
 
Selected individuals, please post any questions you have here in this thread, or PM me. I'd appreciate a PM or post here to confirm when the goods arrive as well. Thanks!
 
Oh calm down, I gotch yer PM. Lay off the RPM :dance:

lol

Apparently, you haven't taken enough RPM to receive my telepathic messages so I will post my questions here;

1. Do I actually have to go to the gym and work out while using NeoVar or will it add muscle to me while I sit here and type?

2. How many female fitness models come with each bottle to help me to remember to take my dose?

3. Should I eat food while cycling NeoVar or should it be avoid for the entire 4 weeks?

4. How much wood could a woodchuck chuck if a woodchuck could chuck wood?

5. Would NeoVar help said woodchuck chuck wood or would that represent a waste of product given that woodchucks can't chuck wood in any appreciable manner?

6. Will NeoVar help me and my goat with our "intimacy" issues?
 
bioman said:
Oh calm down, I gotch yer PM. Lay off the RPM :dance:

lol

Apparently, you haven't taken enough RPM to receive my telepathic messages so I will post my questions here;

1. Do I actually have to go to the gym and work out while using NeoVar or will it add muscle to me while I sit here and type?

Only Drive does that, sorry​

2. How many female fitness models come with each bottle to help me to remember to take my dose?

3, but they were all born as boys​

3. Should I eat food while cycling NeoVar or should it be avoid for the entire 4 weeks?

It works best with just eating 16 oz of dextrose each meal instead of anything else​

4. How much wood could a woodchuck chuck if a woodchuck could chuck wood?

None, because they don't have Drive​

5. Would NeoVar help said woodchuck chuck wood or would that represent a waste of product given that woodchucks can't chuck wood in any appreciable manner?

Yes​

6. Will NeoVar help me and my goat with our "intimacy" issues?

Sorry, perhaps you are just the wrong species yourself (see my avatar)​
Click to expand...
;) :D
 
I have restarted training with some cardio and lighter, higher rep work in anticipation.

It hurrrrrts, oh how it hurrrrts! lol
 
Id log it. I wanted to try a new creatine product anyway. I would put my stats, take pics, log everyday. Whatever you want. Let me know if you are interested.
 
Received the neovar today, I guess I'll take my first dose tomorrow, and open the log tomorrow as well! Thanks :)
 
Lanbane said:
hahaha.... Imprezivr, you aren't going anywhere!
Click to expand...

Neovar has arrived. I will start log tonight or sometime tomorrow. I will start posting results Monday evening after my first workout using neovar. I don't train on the weekends.
 
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