FatalFunnel
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Hey guys, I haven't seen anything TOO informative about Anavar yet on this site and I stumbled across it on one of Scarz's posts over at Steroidology. I thought I'd post it for everyone to see.
"First, id like to get a few things straight about var.
MYTHS
Myth #1 - Anavar will not suppress the HPTA.
False. Anavar, used in adequate dosages, will shut you down. To what degree you experience side effects of suppression (loss of libido, lethargy) is entirely dependent upon the individual and the dosages used.
Myth #2 - Var is a weak anabolic, and is not effective unless stacked with a more androgenic compound.
This could not be further from the truth. At dosages of 40mg a day and higher, anavar is incredibly effective at adding water free LBM. At around day 6-7, increased vascularity should become apparent (assuming your oxandrolone is legitimate in its dosing), and strength gains should start appearing around day 14.
If used during a clean bulk, gains of 10-20 pounds are possible. If cutting, you will maintain weight, or even put on 5-10 pounds (depending on the rate of fat loss/severity of diet). You will keep all of your gains with proper PCT.
Myth #3 - Anavar will not require any type of PCT.
This is one ive never understood. It's a pretty commonly known fact now that var is a suppressive compound. So why is it that some individuals still refuse to make a small investment in some clomid/nolva....this is your testicular function we're talking about. That said, PCT required for var is not as "heavy" as PCT for, say, a test/eq cycle. 15-20 days @ 50mg clomid should be sufficient.
LIBIDO
The only real issue of concern that i have found when running anavar alone is slight libido suppression. Anavar is suppressive enough to where you WILL feel a difference in your sex drive (and not for the better ) when using 40+mg a day. There are three options to counteract this.
#1 - Tribulus + Avena Sativa - Trib at 4-7g a day and Avena Sativa at 3-4g a day tend to help prevent any loss in performance or ability to get it up. However, using effective dosages is going to end up being as or more expensive than options 2 or 3...but its your call.
#2 - Proviron - If hairloss is an issue in your choice to use anavar, then you may want to avoid this one. But 25mg ED proviron, starting after week 2, will keep you rock hard. And it will help to harden up your muscles too .
#3 - Maintenance Test Dosage - Finally, you could choose to use testosterone to keep your willy in shape. At a dosage of around 200mg, split bi weekly, everything should keep running smoothly. Also, this will contribute to your gains much moreso than than options 1 or 2. I would keep nolva onhand on the off chance that you are severely gyno prone. Bloating should not be an issue at this dosage.
BENEFITS
Anavar is a badass drug. This is why.
#1 - Vascularity
Oxandrolone will make you veiny as all hell. And quickly. Look out for brand new bulging forearms veins by around day 6. If you are following a cutting regimen, expect new spider webs in your chest, shoulders and quads by around day 21.
#2 - Pumps
When on var, the pumps are constant. Bored sitting in class/at work? Do some unweighted calf raises. After about three minutes, your calves will be ready to pop. Youll be doing something like drinking a cup of water, and after a minute of holding it, your bi will be completely full and pumped. You may have to cut some sets short in the gym due to the painful pumpage.
#3 - Strength
Even when cutting, you can expect new strength gains every workout after about day 14-21.
#4 - Fat Loss
Anavar has been shown to contribute to accelerated fat loss in both subcutaneous and visceral fat, concentrated effects in the abdomen and thigh area. And if youve used the drug, you can attest to this...if you cant sport the 6-8 pack look on var, its not gonna happen .
CYCLE
Anavar should be run @ at least 40mg a day to see all of the benefits it offers. Dosages upwards of 80mg have been shown to exhibit diminishing returns. Also, i cant imagine the intensity of the pumps at that kind of dosage.
Cycle #1
Anavar 40-50mg ED Weeks 1-8
Tribulus 5-8g ED Weeks 1-12
Avena Sativa 2-4g ED Weeks 1-12
Clomid 50mg ED Weeks 9-11
Cycle #2
Anavar 40-50mg ED Weeks 1-8
Proviron 25mg ED Weeks 3-8
Clomid 50mg ED Weeks 9-11
Cycle #3
Anavar 40-50mg ED Weeks 1-8
Test Prop 50mg EOD Weeks 1-8
Clomid 50mg ED Weeks 9-11
If bulking, Test Enanthate could be substituted for prop, and 100mg could be injected every 3-4 days...however, this could cause more bloating, and complicate PCT timing.
LIVER PROTECTION
Anavar is a 17 Alpha Alkylated steroid, and is toxic. It has been shown to be less toxic than other orals, and is even used as liver treatment for recovering alcoholics. Still, i would limit my time using it to 8 weeks, 10 at the most.
It would be beneficial to you liver to use several different OTC supplements during, and perhaps after your cycle. A few preventive measures never hurt anyone .
1 - Milk Thistle
The classic liver protectant herb.supposedly works by blocking the entrance of harmful substances to liver cells, and hastening their expulsion. Make sure there is a high standardization of Silymarin
2 - R ALA
A powerful antioxidant
3 - NAC
Supports liver function and production of l-glutathione
4 - Vitamin C and E
Antioxidants
5 - LOADS of water
Helps to flush out your entire system
LIPID PROTECTION
Anavar isnt going to kill your cholesterol levels like some drugs (winny being one of the worst), but it may put your LDL/HDL profiles outside of the normal range. There are a few things that help, but as long as your not using 60+mg daily or running it for more than 10 weeks, i would just use flax...
1 - Flax Oil
Consuming lots of omega fatty acids promotes overall health, as well as helping to keep your lipid profile from becoming too bad.
2 - Policosanol
Used at 20mg daily to keep your HDL (good cholesterol) levels from crashing, and your LDL from becoming too high.
3 - Niacin
Preferably the flush free variety. If you wish, niacin can be used at 1-2g ED for a short period post-cycle to normalize HDL levels. Do not use for more than 7-14 days, as liver toxicity can be an issue when using those dosages of niacin for long periods of time.
-------------
Anavar's Anabolic Effects and Liver Safety...
The anabolic androgenic steroid oxandrolone in the treatment of wasting and catabolic disorders: review of efficacy and safety.
Orr R, Fiatarone Singh M.
School of Exercise and Sport Science, Faculty of Health Sciences, The University of Sydney, Sydney, Australia. [email protected]
There has been increasing interest in the development of effective agents that can be safely used to promote anabolism in the clinical setting for patients with chronic wasting conditions as well as in the prevention and treatment of frailty associated with loss of muscle tissue in aging (sarcopenia).One such agent is the anabolic androgenic steroid (AAS) oxandrolone, which has been used in such clinical situations as HIV-related muscle wasting, severe burn injury, trauma following major surgery, neuromuscular disorders and alcoholic hepatitis for over 30 years. In the US, oxandrolone is the only AAS that is US FDA-approved for restitution of weight loss after severe trauma, major surgery or infections, malnutrition due to alcoholic cirrhosis, and Duchenne's or Becker's muscular dystrophy.Our review of the use of oxandrolone in the treatment of catabolic disorders, HIV and AIDS-related wasting, neuromuscular and other disorders provides strong evidence of its clinical efficacy. Improvements in body composition, muscle strength and function, status of underlying disease or recovery from acute catabolic injury and nutritional status are significant in the vast majority of well designed trials. However, oxandrolone has not yet been studied in sarcopenia.Unlike other orally administered C17alpha-alkylated AASs, the novel chemical configuration of oxandrolone confers a resistance to liver metabolism as well as marked anabolic activity. In addition, oxandrolone appears not to exhibit the serious hepatotoxic effects (jaundice, cholestatic hepatitis, peliosis hepatis, hyperplasias and neoplasms) attributed to the C17alpha-alkylated AASs. Oxandrolone is reported to be generally well tolerated and the most commonly documented adverse effects are transient elevations in transaminase levels and reductions in high density lipoprotein cholesterol level.However, optimal risk:benefit ratios for oxandrolone and other agents in its class will need to be refined before widespread clinical acceptance of AASs as a therapeutic option in sarcopenia and other chronic wasting conditions.
---------------------
Oxandrolone(anavar) and Keeping Gains
Oxandrolone induced lean mass gain during recovery from severe burns is maintained after discontinuation of the anabolic steroid.
Demling RH, DeSanti L.
Department of Surgery, Trauma and Burn Center, Brigham & Women's Hospital, 75 Francis Street, Boston, MA 02115, USA. [email protected]
Weight loss and lean mass loss from burn induced catabolism can be more rapidly restored when the anabolic steroid oxandrolone is added to optimum nutrition compared to nutrition alone. Our purpose in this study was to determine whether the regained lean body mass (LBM) is retained 6 months after stopping oxandrolone. Forty-five severe burn patients, entering the recovery phase were randomized into a nutrition group alone or with the addition of oxandrolone, 20mg per day upon admission to the acute burn rehabilitation (RH) unit. Oxandrolone was discontinued after at least 80% of the involuntary weight loss occurring in the acute burn period, was restored. Body composition was measured using bioelectric impedence analysis (BIA). We found that patients receiving oxandrolone, in the rehabilitation unit, regained weight and lean mass two to three times faster than with nutrition alone. The difference was statistically significant (P<0.05). All patients were discharged from RH on a nutrition and exercise program and monitored in the outpatient burn center. After 6 months, body weight and body composition were again measured. We found that the body weight and lean mass which was restored during RH, was maintained 6 months after discontinuation of oxandrolone. Lost lean mass was not yet restored in the nutrition alone group. We can conclude that body weight and lean mass which is lost, due to burn induced catabolism, can be effectively restored in the post-burn recovery period with oxandrolone. The body weight and lost lean mass which is regained, is maintained 6 months after stopping the drug.
-----------------
Anavar is indeed suppressive...the famous study
Effect of low dose oxandrolone and testosterone treatment on the pituitary-testicular and GH axes in boys with constitutional delay of growth and puberty.
Crowne EC, Wallace WH, Moore C, Mitchell R, Robertson WH, Holly JM, Shalet SM.
Department of Endocrinology, Christie Hospital Trust, Manchester, UK.
OBJECTIVE: To investigate the effect of low dose oxandrolone and testosterone on the pituitary-testicular and GH-IGF-I axes. DESIGN: Prospective double-blind placebo-controlled trial. PATIENTS: Sixteen boys with constitutional delay of growth and puberty (CDGP) with testicular volumes 4-6 ml were randomized to 3 months treatment: Group 1 (n = 5), daily placebo: Group 2 (n = 5), 2.5 mg oxandrolone daily or Group 3 (n = 6), 50 mg testosterone monthly intramuscular injections with assessment (growth, pubertal development and overnight hormone profiles) at 0, 3, 6 and 12 months. MAIN OUTCOME MEASURES: LH and GH profiles (15-minute samples) were analysed by peak detection (Pulsar), Fourier transformation and autocorrelation. Testosterone levels were measured hourly and insulin, SHBG, IGF-I, and IGFBP-3 levels at 0800 h. Statistical analysis was by multivariate analysis of variance for repeated measures. RESULTS: LH and testosterone parameters increased significantly with time in all 16 (LH AUC, P < 0.001; peak amplitude, P = 0.02; number of peaks, P = 0.02; testosterone AUC, P = 0.02; morning testosterone, P = 0.002). In Group 2, however, LH and testosterone parameters decreased at 3 months followed by a rebound increase at 6 and 12 months. SHBG levels were markedly reduced at 3 months (P = 0.006) and a wider range of dominant GH frequencies was present although GH AUC was not increased until 6 months, with an increase in GH pulse frequency but not amplitude. IGF-I levels were increased at both 3 and 12 months. In Group 3, pituitary-testicular suppression was not apparent, but GH levels increased with an increase in GH amplitude at 3 and 12 months. CONCLUSION: Oxandrolone transiently suppressed the pituitary-testicular axis and altered GH pulsatility. Testosterone increased GH via amplitude modulation.
ENJOY
:booty:
"First, id like to get a few things straight about var.
MYTHS
Myth #1 - Anavar will not suppress the HPTA.
False. Anavar, used in adequate dosages, will shut you down. To what degree you experience side effects of suppression (loss of libido, lethargy) is entirely dependent upon the individual and the dosages used.
Myth #2 - Var is a weak anabolic, and is not effective unless stacked with a more androgenic compound.
This could not be further from the truth. At dosages of 40mg a day and higher, anavar is incredibly effective at adding water free LBM. At around day 6-7, increased vascularity should become apparent (assuming your oxandrolone is legitimate in its dosing), and strength gains should start appearing around day 14.
If used during a clean bulk, gains of 10-20 pounds are possible. If cutting, you will maintain weight, or even put on 5-10 pounds (depending on the rate of fat loss/severity of diet). You will keep all of your gains with proper PCT.
Myth #3 - Anavar will not require any type of PCT.
This is one ive never understood. It's a pretty commonly known fact now that var is a suppressive compound. So why is it that some individuals still refuse to make a small investment in some clomid/nolva....this is your testicular function we're talking about. That said, PCT required for var is not as "heavy" as PCT for, say, a test/eq cycle. 15-20 days @ 50mg clomid should be sufficient.
LIBIDO
The only real issue of concern that i have found when running anavar alone is slight libido suppression. Anavar is suppressive enough to where you WILL feel a difference in your sex drive (and not for the better ) when using 40+mg a day. There are three options to counteract this.
#1 - Tribulus + Avena Sativa - Trib at 4-7g a day and Avena Sativa at 3-4g a day tend to help prevent any loss in performance or ability to get it up. However, using effective dosages is going to end up being as or more expensive than options 2 or 3...but its your call.
#2 - Proviron - If hairloss is an issue in your choice to use anavar, then you may want to avoid this one. But 25mg ED proviron, starting after week 2, will keep you rock hard. And it will help to harden up your muscles too .
#3 - Maintenance Test Dosage - Finally, you could choose to use testosterone to keep your willy in shape. At a dosage of around 200mg, split bi weekly, everything should keep running smoothly. Also, this will contribute to your gains much moreso than than options 1 or 2. I would keep nolva onhand on the off chance that you are severely gyno prone. Bloating should not be an issue at this dosage.
BENEFITS
Anavar is a badass drug. This is why.
#1 - Vascularity
Oxandrolone will make you veiny as all hell. And quickly. Look out for brand new bulging forearms veins by around day 6. If you are following a cutting regimen, expect new spider webs in your chest, shoulders and quads by around day 21.
#2 - Pumps
When on var, the pumps are constant. Bored sitting in class/at work? Do some unweighted calf raises. After about three minutes, your calves will be ready to pop. Youll be doing something like drinking a cup of water, and after a minute of holding it, your bi will be completely full and pumped. You may have to cut some sets short in the gym due to the painful pumpage.
#3 - Strength
Even when cutting, you can expect new strength gains every workout after about day 14-21.
#4 - Fat Loss
Anavar has been shown to contribute to accelerated fat loss in both subcutaneous and visceral fat, concentrated effects in the abdomen and thigh area. And if youve used the drug, you can attest to this...if you cant sport the 6-8 pack look on var, its not gonna happen .
CYCLE
Anavar should be run @ at least 40mg a day to see all of the benefits it offers. Dosages upwards of 80mg have been shown to exhibit diminishing returns. Also, i cant imagine the intensity of the pumps at that kind of dosage.
Cycle #1
Anavar 40-50mg ED Weeks 1-8
Tribulus 5-8g ED Weeks 1-12
Avena Sativa 2-4g ED Weeks 1-12
Clomid 50mg ED Weeks 9-11
Cycle #2
Anavar 40-50mg ED Weeks 1-8
Proviron 25mg ED Weeks 3-8
Clomid 50mg ED Weeks 9-11
Cycle #3
Anavar 40-50mg ED Weeks 1-8
Test Prop 50mg EOD Weeks 1-8
Clomid 50mg ED Weeks 9-11
If bulking, Test Enanthate could be substituted for prop, and 100mg could be injected every 3-4 days...however, this could cause more bloating, and complicate PCT timing.
LIVER PROTECTION
Anavar is a 17 Alpha Alkylated steroid, and is toxic. It has been shown to be less toxic than other orals, and is even used as liver treatment for recovering alcoholics. Still, i would limit my time using it to 8 weeks, 10 at the most.
It would be beneficial to you liver to use several different OTC supplements during, and perhaps after your cycle. A few preventive measures never hurt anyone .
1 - Milk Thistle
The classic liver protectant herb.supposedly works by blocking the entrance of harmful substances to liver cells, and hastening their expulsion. Make sure there is a high standardization of Silymarin
2 - R ALA
A powerful antioxidant
3 - NAC
Supports liver function and production of l-glutathione
4 - Vitamin C and E
Antioxidants
5 - LOADS of water
Helps to flush out your entire system
LIPID PROTECTION
Anavar isnt going to kill your cholesterol levels like some drugs (winny being one of the worst), but it may put your LDL/HDL profiles outside of the normal range. There are a few things that help, but as long as your not using 60+mg daily or running it for more than 10 weeks, i would just use flax...
1 - Flax Oil
Consuming lots of omega fatty acids promotes overall health, as well as helping to keep your lipid profile from becoming too bad.
2 - Policosanol
Used at 20mg daily to keep your HDL (good cholesterol) levels from crashing, and your LDL from becoming too high.
3 - Niacin
Preferably the flush free variety. If you wish, niacin can be used at 1-2g ED for a short period post-cycle to normalize HDL levels. Do not use for more than 7-14 days, as liver toxicity can be an issue when using those dosages of niacin for long periods of time.
-------------
Anavar's Anabolic Effects and Liver Safety...
The anabolic androgenic steroid oxandrolone in the treatment of wasting and catabolic disorders: review of efficacy and safety.
Orr R, Fiatarone Singh M.
School of Exercise and Sport Science, Faculty of Health Sciences, The University of Sydney, Sydney, Australia. [email protected]
There has been increasing interest in the development of effective agents that can be safely used to promote anabolism in the clinical setting for patients with chronic wasting conditions as well as in the prevention and treatment of frailty associated with loss of muscle tissue in aging (sarcopenia).One such agent is the anabolic androgenic steroid (AAS) oxandrolone, which has been used in such clinical situations as HIV-related muscle wasting, severe burn injury, trauma following major surgery, neuromuscular disorders and alcoholic hepatitis for over 30 years. In the US, oxandrolone is the only AAS that is US FDA-approved for restitution of weight loss after severe trauma, major surgery or infections, malnutrition due to alcoholic cirrhosis, and Duchenne's or Becker's muscular dystrophy.Our review of the use of oxandrolone in the treatment of catabolic disorders, HIV and AIDS-related wasting, neuromuscular and other disorders provides strong evidence of its clinical efficacy. Improvements in body composition, muscle strength and function, status of underlying disease or recovery from acute catabolic injury and nutritional status are significant in the vast majority of well designed trials. However, oxandrolone has not yet been studied in sarcopenia.Unlike other orally administered C17alpha-alkylated AASs, the novel chemical configuration of oxandrolone confers a resistance to liver metabolism as well as marked anabolic activity. In addition, oxandrolone appears not to exhibit the serious hepatotoxic effects (jaundice, cholestatic hepatitis, peliosis hepatis, hyperplasias and neoplasms) attributed to the C17alpha-alkylated AASs. Oxandrolone is reported to be generally well tolerated and the most commonly documented adverse effects are transient elevations in transaminase levels and reductions in high density lipoprotein cholesterol level.However, optimal risk:benefit ratios for oxandrolone and other agents in its class will need to be refined before widespread clinical acceptance of AASs as a therapeutic option in sarcopenia and other chronic wasting conditions.
---------------------
Oxandrolone(anavar) and Keeping Gains
Oxandrolone induced lean mass gain during recovery from severe burns is maintained after discontinuation of the anabolic steroid.
Demling RH, DeSanti L.
Department of Surgery, Trauma and Burn Center, Brigham & Women's Hospital, 75 Francis Street, Boston, MA 02115, USA. [email protected]
Weight loss and lean mass loss from burn induced catabolism can be more rapidly restored when the anabolic steroid oxandrolone is added to optimum nutrition compared to nutrition alone. Our purpose in this study was to determine whether the regained lean body mass (LBM) is retained 6 months after stopping oxandrolone. Forty-five severe burn patients, entering the recovery phase were randomized into a nutrition group alone or with the addition of oxandrolone, 20mg per day upon admission to the acute burn rehabilitation (RH) unit. Oxandrolone was discontinued after at least 80% of the involuntary weight loss occurring in the acute burn period, was restored. Body composition was measured using bioelectric impedence analysis (BIA). We found that patients receiving oxandrolone, in the rehabilitation unit, regained weight and lean mass two to three times faster than with nutrition alone. The difference was statistically significant (P<0.05). All patients were discharged from RH on a nutrition and exercise program and monitored in the outpatient burn center. After 6 months, body weight and body composition were again measured. We found that the body weight and lean mass which was restored during RH, was maintained 6 months after discontinuation of oxandrolone. Lost lean mass was not yet restored in the nutrition alone group. We can conclude that body weight and lean mass which is lost, due to burn induced catabolism, can be effectively restored in the post-burn recovery period with oxandrolone. The body weight and lost lean mass which is regained, is maintained 6 months after stopping the drug.
-----------------
Anavar is indeed suppressive...the famous study
Effect of low dose oxandrolone and testosterone treatment on the pituitary-testicular and GH axes in boys with constitutional delay of growth and puberty.
Crowne EC, Wallace WH, Moore C, Mitchell R, Robertson WH, Holly JM, Shalet SM.
Department of Endocrinology, Christie Hospital Trust, Manchester, UK.
OBJECTIVE: To investigate the effect of low dose oxandrolone and testosterone on the pituitary-testicular and GH-IGF-I axes. DESIGN: Prospective double-blind placebo-controlled trial. PATIENTS: Sixteen boys with constitutional delay of growth and puberty (CDGP) with testicular volumes 4-6 ml were randomized to 3 months treatment: Group 1 (n = 5), daily placebo: Group 2 (n = 5), 2.5 mg oxandrolone daily or Group 3 (n = 6), 50 mg testosterone monthly intramuscular injections with assessment (growth, pubertal development and overnight hormone profiles) at 0, 3, 6 and 12 months. MAIN OUTCOME MEASURES: LH and GH profiles (15-minute samples) were analysed by peak detection (Pulsar), Fourier transformation and autocorrelation. Testosterone levels were measured hourly and insulin, SHBG, IGF-I, and IGFBP-3 levels at 0800 h. Statistical analysis was by multivariate analysis of variance for repeated measures. RESULTS: LH and testosterone parameters increased significantly with time in all 16 (LH AUC, P < 0.001; peak amplitude, P = 0.02; number of peaks, P = 0.02; testosterone AUC, P = 0.02; morning testosterone, P = 0.002). In Group 2, however, LH and testosterone parameters decreased at 3 months followed by a rebound increase at 6 and 12 months. SHBG levels were markedly reduced at 3 months (P = 0.006) and a wider range of dominant GH frequencies was present although GH AUC was not increased until 6 months, with an increase in GH pulse frequency but not amplitude. IGF-I levels were increased at both 3 and 12 months. In Group 3, pituitary-testicular suppression was not apparent, but GH levels increased with an increase in GH amplitude at 3 and 12 months. CONCLUSION: Oxandrolone transiently suppressed the pituitary-testicular axis and altered GH pulsatility. Testosterone increased GH via amplitude modulation.
ENJOY
:booty:
