I just got my LEF lab work. -labcorp
98mg test cyp per week as 28mg IM EOD, (#29 .5" .5ml)
250iu HCG SQ EOD, (#29 .5" .5ml)
1mg/wk of anastrozole in EOD doses
FT 36.1 (3.5%)
DHEA-s 668 (70-310)
Thyroid: -looks good
TSH 1.303 (.35-5.500)
T4 5.4 (4.5-12.0)
T3 3.2 (2.3-12.0) would report as 320 at some labs
Free T4 1.32 (0.61-1.76)
Iron is high 239 (40-155), was low 3.5 years ago
hematocrit is 46%, was 44% before TRT, so no significant change
Anyone ever hear of TRT pushing up iron?
I had been sick a month before, lost 5 pounds and 103.6 fever. Does tissue/muscle loss release iron?
I had an elevated serum iron reading 2-3 years ago. My doc had me look at the labels of my supps. It turns out my multi-vit contained iron and I was also taking a separate multi-mineral that also contained iron. I stopped taking both and retested in 3 mos. Serum iron had returned to normal.
While TRT can cause polycythemia, I haven't heard that it can cause elevated iron levels.
You need to get to the bottom of this. Iron overload is a serious thing.
My doc screened me for hemochromatosis - I think the tests he ran were serum ferritin and total iron binding capacity, in addition to serum iron.
Ksman, iron like alot of minerals are metabolized by the liver - maybe something is going on there.
Maybe your liver is a little overtaxed with all the supplementation you have going on? I know you take alot of other supps other than TRT drugs.
Alot of other things as well can cause a sluggish liver. Environmental toxins, prior AAS and/or alcohol use, extended prescription drug use(painkillers are notorious for this), metal fillings in teeth, etc.
You better have your ferritin checked!!
It sounds like you VERY may have Hereditary hemochormatosis.
I have it and Its is EXTREMELY comman and extremely undiagnosed, leading to very low T, heart disease, liver cancer.etc etc etc, your rusting from the inside out.
AND since its hereditary 4 out of 5 of my family were tested and HAVE it.
treatment is simple, phlebotomies. Hemocromatosis is what caused my secondary hypogonadism (alcohol didnt help either)
But Dr. John is treating my hormones
A LEF Doc reviewed my BW today. Liver and kidney markers are great. I ordered some iron-free lactoferrin and donated blood this afternoon. So I am off to a good start. Note that most lactoferrin that you will find already has a high load of iron. LEF was the only place that I could find that had de-ironed lactoferrin. LEF is selling that at a large discount now.
I was not able to give blood for a bit over a year after travelling to Mexico in a 'yellow book' malaria risk area. So I do have the relative advantage of getting back onto regular blood donations. BTW, the blood bank does not see any issues with self injected T and HCG that is prescribed.
Damn Cheerios has 45% daily iron requirements! Funny thing is that 3.5 years ago a LEF doc told be my iron was low... and it was. Doc agreed today that my iron was an issue, suggested the lactoferrin. I can take some oral EDTA as well. He also stated that all of the other blood markers that might indicate a problem from the iron were looking fine.
Zinc and copper compete for iron absorption. Calcium as well, which should be taken with your meals. Calcium also binds oxalic acid which means that it cannot be absorbed. So taking calcium with meals mean that you can keep calcium oxalate out of your blood stream and reduce chances of the major type of kidney stone. (I just hijacked my own post
I am doing it for couple of years and while getting good advice I am not totally impressed with the process of getting that advice.
Could you describe your approach.
They usually do not like to have blood work be send to them.
They answer my questions but are not pro-active.
Producing good question is already half of the answer so I am missing a lot if I have to ask questions.
Update from BW review with my doctor - an age management specialist and enthusiast.
He was ok with my anti iron: blood donations, lactoferrin and EDTA as well as avoiding iron enriched foods like "heart friendly" Cheerios.
He was perfectly understanding with my doing BW with LEF.org, given the lack of insurance and the cost savings. And he is the director of the in-house lab too.
He was totally ok with my high[er] T and FT levels and explained what the optimal ranges were.
He agreed that it would be good to shoot for E2=17-20 with 1.2mg/wk of anastrozole. I also pointed out my E2=17 from 2004.
We reviewed the thyroid levels and he suggested that I try 30mg/day of Armour to get into optimal range. He thought that my T3 was at the lower end of what he considers optimal range. We also discussed my lack of energy as consistent with this. Thanks to others here who have suggested that I explore that. I did take note of the suggestions here to take in 2 or 3 sub-doses during the day. (Probably do not want to feel stimulated at bed time either.) This thyroid will be new for me. He explained that I might get some heart paps (rare), a pick-up in vitality, then perhaps a drop as the feedback mechanism compensates, perhaps a while of overcompensation, then a bound up to a steady state. Sounds like a balance might take around 4-6 weeks and it take a while to eval things.
Explained how libido and virility can wane sometimes. He is getting me a tube of compounded T cream (don't know the strength yet) to use as pick-me-up to see how I respond to that.
We talked up a storm about things related like congress trying to make DHEA a schedule III drug, some doctors who don't know and don't care.
I had two pages of observations about my HRT since my last visit and he carefully goes through every item and picks up on things significant.
Got my scripts and blood work plans for the next 12 months so I can purchase LEF blood work that is on sale till the end of May.
I am so fortunate to have this doctor.
Sounds great Ksman, you sir are an irreplacable fountain of experience/knowledge.
I haven't done a whole lot of research on thyroid issues. My thyroid panel is exactly the same as yours. That was taken though in 10/06, when i was basically a nicotine/caffeine junkie. Let us all know how you respond. The thyroid thing is something I will let Dr John dictate for me.
Remember, thyroid functioning and TD respondness go hand in hand. So as your thyroid improves the T cream will probably work. Are you going threw a compounding pharmacy? Thats were I will probably go threw, as in I have a very large one right here in metro detroit.
You eat cereal? Cereal and milk for me now are just memories of childhood.
I am beginning to think that my elevated estradoil(43) is the root of issues along with IGF-1. As my T has increased, not much has changed. Im way to estrogen dominant.