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Higher ArA dosage, or ArA stack?

bmoore

bmoore

New member
Few months ago I ran x-gels for 50 days. I started at 1g a day and went up to 1.5g. Do y'all think it would be more beneficial, from a recomp standpoint, to up the dosage to 2g a day or stack it with gms and alcar?
 
It'd be more beneficial to add the GMS and Carnitine IMO.
 
Misfit28 said:
Quick question. I have seen the GMS listed at 6g before. That seemed high to me, and could possibly cause stomach problems, correct?

If so, I'm going to go with the 3g. Thanks for the info!
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Go with a 5-lpo inhibitor and hca for the next time you use it with GMS and carnitine.

Muscular uptake and amount of ara In the stem would be high,
 
EBF Inc said:
Go with a 5-lpo inhibitor and hca for the next time you use it with GMS and carnitine. Muscular uptake and amount of ara In the stem would be high,
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Metabolic powder pre with ArA? The MP recommended dose good?
 
De__eB said:
Invalid Link Removed Among other places
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Off topic question: What are your thoughts on taking ArA + carbs (~30g) + leucine first thing in the AM and lifting shortly after? Will that transient increase in insulin shift the likelihood of ArA being delivered to skeletal muscle?
 
I think I read somewhere in that thread that insulin + ArA = ArA not delivered to skeletal muscle. Is that correct?
 
aaronuconn said:
I'm talking taking it in a preworkout setting along with carbs + leucine though.
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In for reply. I believe someone had told me not to worry about it too much, but no CHO amounts were given.

Anecdotally I have done ArA + GMS + LCLT pre and up to 50g of CHO during a session with some very positive results.
 
I have also read that taking Baby aspirin can help with the effects of ArA. Just one 81mg tablet per day.

I think you are supposed to start taking the aspirin before starting the ArA by 10 days, then continue to take it during your run.

Edit: Found it!! This is from another forum.

"Quoting Coop, yet again.

Re-read the benefits of aspirin mentioned ITT:


1. Blockade of TxA2 formation = vasodilation -> performance enhancement
2. Increased availability of ArA for non-thrombotic endpoints
3. Stimulation of AMPK and overall health benefits

Are the effects of 81mg aspirin significant when it comes to ArA metabolism? Absolutely. You and I both know it's one of the most well-studied drugs in existence"
 
Misfit28 said:
I have also read that taking Baby aspirin can help with the effects of ArA. Just one 81mg tablet per day.

I think you are supposed to start taking the aspirin before starting the ArA by 10 days, then continue to take it during your run.

Edit: Found it!! This is from another forum.

"Quoting Coop, yet again.

Re-read the benefits of aspirin mentioned ITT:

1. Blockade of TxA2 formation = vasodilation -> performance enhancement
2. Increased availability of ArA for non-thrombotic endpoints
3. Stimulation of AMPK and overall health benefits

Are the effects of 81mg aspirin significant when it comes to ArA metabolism? Absolutely. You and I both know it's one of the most well-studied drugs in existence"
Click to expand...

To be technical;

COX and LPO breakdown the ArA into the luekotrienes and thromboxanes

Inhibiting them (5-LPO and COX-2 inhibitor) leaves more Arachidonic acid available for uptake into muscle cells. This would be a good thing.

However, as far as vasodilation, the increase of breakdown to 2-ag and aea (anandamide via FAAH (fatty acid amide hydroxilase) also aids in vasodilation via trpv1 agonism. So it can work both ways


This may also be where garcinia Cambogia (50% hca) can play into effect in the cellular uptake but via a different mechanism (CD36).
 
Misfit28 said:
I have also read that taking Baby aspirin can help with the effects of ArA. Just one 81mg tablet per day.

I think you are supposed to start taking the aspirin before starting the ArA by 10 days, then continue to take it during your run.

Edit: Found it!! This is from another forum.

"Quoting Coop, yet again.

Re-read the benefits of aspirin mentioned ITT:


1. Blockade of TxA2 formation = vasodilation -> performance enhancement
2. Increased availability of ArA for non-thrombotic endpoints
3. Stimulation of AMPK and overall health benefits

Are the effects of 81mg aspirin significant when it comes to ArA metabolism? Absolutely. You and I both know it's one of the most well-studied drugs in existence"
Click to expand...
This is correct. Others use Carnitine in place of the aspirin.
 
Misfit28 said:
Oh, ok. So if I already take Anavite, I won't need the baby aspirin?

Would it hurt/help to do both?
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I would do one or the other. No need to run both if you have 2g carnitine already available
 
aaronuconn said:
Off topic question: What are your thoughts on taking ArA + carbs (~30g) + leucine first thing in the AM and lifting shortly after? Will that transient increase in insulin shift the likelihood of ArA being delivered to skeletal muscle?
Click to expand...

I would not advise it.
 
Interested in tho as I was considering this on my next run
 
EBF Inc said:
Go with a 5-lpo inhibitor and hca for the next time you use it with GMS and carnitine.

Muscular uptake and amount of ara In the stem would be high,
Click to expand...

How about Lodhra Bark (symplocos racemosa extract) as a lipoxygenase inhibitor?

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If so ArA + Anabeta elite + metabolic powder might nake for a good stack
 
So your saying use AA and anebeta elite together with alcat
 
BPjohn123 said:
They would stack very well
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Yup. As pointed out by EBF Inc

EBF Inc said:
COX and LPO breakdown the ArA into the luekotrienes and thromboxanes

Inhibiting them (5-LPO and COX-2 inhibitor) leaves more Arachidonic acid available for uptake into muscle cells. This would be a good thing.
Click to expand...

So when we take ArA some of it gets broken down into luekotrienes and thromboxanes via LPO and COX. Now if we could inhibit both of them it would result in more ArA to stay which meams there is more that could be used by our muscles

So the proposed above stack would inhibit ArA being broken down into thromboxanes via l-carnitine ( Invalid Link Removed) and inhibit ArA being broken down into luekotrienes via anabeta elite (Invalid Link Removed)

So l-carnitine and anabeta elite would create the enviroment for optimal available ArA.

Now also, as pointed out by EBF Inc

EBF Inc said:
This may also be where garcinia Cambogia (50% hca) can play into effect in the cellular uptake but via a different mechanism (CD36).
Click to expand...

So we add HCA to help all that now extra ArA to be able to get used by our muscles

Hence the stack of ArA + Anabeta Elite + l-carnitine + metabolic powder
 
MultiVitamin said:
And so you'd reccomend this all pre-workout? Aren't ABE & MP meant to be taken with food?
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ABE is recommended pre-workout. MP is also recommended pre-workout. Both can be taken with or without food.
 
Synapsin said:
Yes, that would be fine.

Short on time, but I will get into it later if I remember. I'm sure Cyrus or someone else can explain if they have time (assuming they're asked nicely :) ).
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I actually just read a study while I was searching showing some sort of blunted effects in the presence of insulin maybe on the prostaglandin formation. **** I wish I remembered
 
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