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Who wants the NEW PES Fat Burner to launch at Nutraplanet?

Looks great but $69? That's a little pricey for me. I'm gonna want to stack it with Alpha t2 and possible Erase so that would be way to much money for me to spend on supplements.
I love PES products but that's just out of my price range. I could but Chicken for weeks with that price.
 
Geoforce said:
The reviews on NP are really annoying. A 3.0/5.0 with 4 votes for a product that hasn't been released yet and just had the ingredients put up on the site. I get just as annoyed by new products with magical 5.0 stars everywhere.

Ok, enough grouching, bring on the Alphamine Fruit Punch I ordered :)
Click to expand...

You are so right. If I haven't already decided to try a product before it comes out, I look at logs or thorough reviews from users I trust. I also lend a lot of credence to what reps have to say since they usually get to try the products first and most are not going to steer you into something they know you are not going to be happy with. I'll skip the random store reviews from nameless, faceless people that I don't know.
 
Mrpersinality said:
Looks great but $69? That's a little pricey for me. I'm gonna want to stack it with Alpha t2 and possible Erase so that would be way to much money for me to spend on supplements.
I love PES products but that's just out of my price range. I could but Chicken for weeks with that price.
Click to expand...

They aren't selling it for $69. I will likely be available for around half of that.
 
Mrpersinality said:
Looks great but $69? That's a little pricey for me. I'm gonna want to stack it with Alpha t2 and possible Erase so that would be way to much money for me to spend on supplements.
I love PES products but that's just out of my price range. I could but Chicken for weeks with that price.
Click to expand...

Like Dewey said, it won't retail for that. I would guess it will be in the 30-38 dollar range if I had to lay a wager, but that's just an educated guess.
 
Geoforce said:
Like Dewey said, it won't retail for that. I would guess it will be in the 30-38 dollar range if I had to lay a wager, but that's just an educated guess.
Click to expand...

That's great news because I'm deff interested in this product looks solid like everything else they carry.
 
Mrpersinality said:
That's great news because I'm deff interested in this product looks solid like everything else they carry.
Click to expand...

Nutra has the Presale up now. Under $30, grab it while its that cheap!
 
In Celebration of Invalid Link Removed, NutraPlanet Proudly Introduces The Invalid Link Removed, AT AN INSANELY LOW INTRODUCTORY SALE PRICE!

**THIS OFFER EXPIRES SOON, SO DON'T DELAY!**

Invalid Link Removed
 PES' NEW Alphamine: Innovative & Powerful Thermogenic Powder!
After two years of undeniable feedback from Alpha-T2, we sat down to begin our research onto an even greater, more innovative, more powerful fat burner... We realized all the fat burners on the market hold MAJOR flaws...we set out to create a solution. In search for our goal, we stumbled across the most effective and innovative formulation that has EVER been introduced......And with that said, PES' NEW Alphamine was born! ALPHAMINE is a revolutionary fat loss product with no other comparison! Here are just a few reasons why....Invalid Link Removed
​

VERY LIMITED TIME INTRODUCTORY PRE-SALE PRICE: ETA- 8/24
Invalid Link RemovedInvalid Link RemovedInvalid Link Removed
Reg Price: $69.99
Sale Price: $29.99
You SAVE 57%!!!
 

Attachments

  • Alphamine Sale Banner.jpeg
    Alphamine Sale Banner.jpeg
    89.1 KB · Views: 189
Also, as another part of the "PES FOR LIFE" SALEathon CELEBRATION Series, we are basically GIVING AWAY Invalid Link Removed!!! .....FOR 1 WEEK ONLY, Invalid Link Removed for the LOWEST PRICE EVER, ANYWHERE!!! (Offer Expires 8/21)

Invalid Link RemovedONLY $39.99!!!

Invalid Link Removed

Key Benefits:

  • Underground Hormone Modulator
  • Extreme Muscle Hardening Agent
  • Potent Anti-Catabolic
  • Test-Estro-Cort Synergism
  • Synthetic High Affinity AI
  • SERM-etic Technology
 
Niceee! Everyone needs to get in on these specials while theyre hot!
 
Geoforce said:
The reviews on NP are really annoying. A 3.0/5.0 with 4 votes for a product that hasn't been released yet and just had the ingredients put up on the site. I get just as annoyed by new products with magical 5.0 stars everywhere.

Ok, enough grouching, bring on the Alphamine Fruit Punch I ordered :)
Click to expand...

This makes me sad. I say we trace their IPs and see who is putting our products down!
 
I would think Nutra would have an interest in just that.
 
bdcc said:
This makes me sad. I say we trace their IPs and see who is putting our products down!
Click to expand...

What if it's one of your own though? A mole!

It happens a lot. You'll see unreleased products with 12 reviews and all 5 starred or something like this where clearly somebody is putting one star reviews for whatever reasons. Competition and all that, but really a somewhat broken review system.
 
Geoforce said:
The reviews on NP are really annoying. A 3.0/5.0 with 4 votes for a product that hasn't been released yet and just had the ingredients put up on the site. I get just as annoyed by new products with magical 5.0 stars everywhere.

Ok, enough grouching, bring on the Alphamine Fruit Punch I ordered :)
Click to expand...

I take it as a compliment. Formula so good people go out of their way to fake-rate it bad
 
nattydisaster said:
I take it as a compliment. Formula so good people go out of their way to fake-rate it bad
Click to expand...

Let alone that, Your ideas are living inside someone's head without paying rent haha. That's how much importance they give yah, hence it just means the formula is so good even the competition can't help but to try to smack you :p all they do is give yah free publicity.
 
ralfman5 said:
This is over hyped.. Where are the experiments proving this supplement does what it claims?
Click to expand...

PES makes quality Supps and for only $30 I think I can run my own "experiment".
 
Lol PES is known for NOT overhyping.
 
NutraPlanet CS said:
In Celebration of Invalid Link Removed, NutraPlanet Proudly Introduces The Invalid Link Removed, AT AN INSANELY LOW INTRODUCTORY SALE PRICE!

**THIS OFFER EXPIRES SOON, SO DON'T DELAY!**

Invalid Link Removed
PES' NEW Alphamine: Innovative & Powerful Thermogenic Powder!
After two years of undeniable feedback from Alpha-T2, we sat down to begin our research onto an even greater, more innovative, more powerful fat burner... We realized all the fat burners on the market hold MAJOR flaws...we set out to create a solution. In search for our goal, we stumbled across the most effective and innovative formulation that has EVER been introduced......And with that said, PES' NEW Alphamine was born! ALPHAMINE is a revolutionary fat loss product with no other comparison! Here are just a few reasons why....Invalid Link Removed


VERY LIMITED TIME INTRODUCTORY PRE-SALE PRICE: ETA- 8/24
Invalid Link RemovedInvalid Link RemovedInvalid Link Removed
Reg Price: $69.99
Sale Price: $29.99
You SAVE 57%!!!
Click to expand...

Ahhh ****!
 
ralfman5 said:
This is over hyped.. Where are the experiments proving this supplement does what it claims?
Click to expand...

I appreciate your skepticism. With all due respect you have this the wrong way round. The research is what we base the ingredients on. We pick ones that have science behind them rather than creating a product and then conducting studies on it.

We are known for bringing innovation backed by research and not for hyping something that doesn't work.

If you have any specific questions please do not hesitate to send me a PM.

Ben
 
ralfman5 said:
This is over hyped.. Where are the experiments proving this supplement does what it claims?
Click to expand...

This might not be "experiments" for the overall product, but definitely legit references for each ingredient.....I think when people do the math, even before trying it, it makes sense......I can assure you of this....PES would NOT come out with a crappy product....EVER. I know them too well.

[h=3]Alphamine References:[/h] Berlan M, Galitzky J, Riviere D, et al. Plasma catecholamine levels and lipid mobilization induced by yohimbine in obese and non-obese women. Int J Obes. 1991 May;15(5):305-315
Galitzky J, Taouis M, Berlan M, et al. Alpha 2-antagonist compounds and lipid mobilization: evidence for a lipid mobilizing effect of oral yohimbine in healthy male volunteers. Eur J Clin Invest. 1988 Dec;18(6):587-594
Flechtner-Mors M, Jenkinson CP, Alt A, et al. In vivo alpha(1)-adrenergic lipolytic activity in subcutaneous adipose tissue of obese subjects. J Pharmacol Exp Ther. 2002 Apr;301(1):229-233
Sax L. Yohimbine does not affect fat distribution in men. Int J Obes. 1991 Sep;15(9):561-565
Kucio C, Jonderko K, Piskorska D. Does yohimbine act as a slimming drug? Isr J Med Sci. 1991 Oct;27(10):550-556
Berlin I, Stalla-Bourdillon A, Thuillier Y, et al. Lack of efficacy of yohimbine in the treatment of obesity. J Pharmacol. 1986 Jul-Sep;17(3):343-347
Zahorska-Markiewicz B, Kucio C, et al. Adrenergic control of lipolysis and metabolic responses in obesity. Horm Metab Res. 1986 Oct;18(10):693-697
Perry BD, U’Prichard DC. [3H]rauwolscine (alpha-yohimbine): a specific antagonist radioligand for brain alpha 2-adrenergic receptors. Eur J Pharmacol. 1981 Dec 17;76(4):461-464
Berlan M, Le Verge R, Galitzky J, et al. Alpha 2-adrenoceptor antagonist potencies of two hydroxylated metabolites of yohimbine. Br J Pharmacol. 1993 Apr;108(4):927-932
Chang KC, Lim JK and Park CW (1986) Synthesis of higenamine and its cardiovascular effects in rabbit: Evidence for b-adrenoceptor agonist. Kor J Pharmacol 22:96 –104
A study on the mechanism of the yang-tonic effect of higenamine. Xiang Rong. Yi Ningyu. Xia Zongqin. PHARMACOLOGY AND CLINICS OF CHINESE MATERIA MEDICA. 1994-06
The Chinese Journal of Clinical Pharmacology, 2007-04. Tolerability of higenamine hydrochloride in healthy volunteers. Yan-rong, Fang, Ri-yi,Yan, OUYANG, Meng, Hong-li.
Eur J Nucl Med. 1983;8(6):233-6. Measurement of effects of the Chinese herbal medicine higenamine on left ventricular function using a cardiac probe. Liu XJ, Wagner HN Jr, Tao S. Planta Med 2009; 75(13): 1393-1399. β2-Adrenoceptor-Mediated Tracheal Relaxation Induced by Higenamine from Nandina domestica Thunberg Muneo Tsukiyama, Takuro Ueki, Yoichi Yasuda, Hiroko Kikuchi, Tatsuhiro Akaishi, Hidenobu Okumura, Kazuho Abe.
CHINESE PHARMACOLOGICAL BULLETIN 1995-02. The pharmacologic action of higenamine on beta-adrenergic receptors in heart of mice. XIANG Rong; XU Jiang-Tao; YI Nin-Yu; XIA Zhong-Qin
Acta Pharmacol Sin 2008 Oct; 29 (10): 1187–1194. Identification of higenamine in Radix Aconiti Lateralis Preparata as a beta2-adrenergic receptor agonist. Gang BAI, Yang YANG, Qian SHI, Ze LIU, Qi ZHANG, Yuan-yuan ZHU
Acta Pharmaceutica Sinica. 1982-09. EFFECTS OF dl-DEMETHYL COCLAURINE ON β-ADRENERGIC RECEPTORS AND ADENYLATE CYCLASE IN TURKEY ERYTHROCYTE MEMBRANE. FENG Yi-pu, JIA Hong-jun, ZHANG Li-ying and ZENG Gui-yun
An Experimental Study on Adrenergic Effect of Higenamine in Rabbit Cardiovascular System. Nam Su Kim,Chang Yee Hong,Chan Woong Pak,Jung Kyoo Lim. Korean Circ J 1986;16:1-18
Diepvens K, Westerterp KR, Westerterp-Plantenga MS. Obesity and thermogenesis related to the consumption of caffeine, ephedrine, capsaicin, and green tea. Am J Physiol Regul Integr Comp Physiol. 2007 Jan;292(1):R77-85
Bracco D, Ferrarra JM, Arnaud MJ, et al. Effects of caffeine on energy metabolism, heart rate, and methylxanthine metabolism in lean and obese women. Am J Physiol. 1995 Oct;269(4 Pt 1):E671-E678
Dullo AG, Geissler CA, Horton T, et al. Normal caffeine consumption: influence on thermogenesis and daily energy expenditure in lean and postobese human volunteers. Am J Clin Nutr. 1989 Jan;49(1):44-50
Acheson KJ, Gremaud G, Meirim I, et al. Metabolic effects of caffeine in humans: lipid oxidation or futile cycling? Am J Clin Nutr. 2004 Jan;79(1):40-46
Kaplan GB, Greenblatt DJ, Ehrenberg BL, et al. Dose-dependent pharmacokinetics and psychomotor effects of caffeine in humans. J Clin Pharmacol. 1997 Aug;37(8):693-703
Smith A. Effects of caffeine on human behavior. Food Chem Toxicol. 2002 Sep;40(9):1243-1255
Robertson D, Frolich JC, Carr RK, et al. Effects of caffeine on plasma renin activity, catecholamines and blood pressure. N Engl J Med. 1978 Jan 26;298(4):181-186
Oleuropein, a Phenolic Compound in Extra Virgin Olive Oil, Increases Uncoupling Protein 1 Content in Brown Adipose Tissue and Enhances Noradrenaline and Adrenaline Secretions in Rats. Yuriko Oi-KANO, Teruo KAWADA, Tatsuo WATANABE, Fumihiro KOYAMA, Kenichi WATANABE, Reijirou SENBONGI, Kazuo IWAI. Journal of Nutritional Science and Vitaminology Vol. 54 (2008) No. 5 P 363-370
Olive leaf extract attenuates cardiac, hepatic, and metabolic changes in high carbohydrate-, high fat-fed rats. Poudyal H, Campbell F, Brown L. J Nutr. 2010 May;140(5):946-53. Epub 2010 Mar 24.
Effect of freeze dried extract of Olea europaea on the pituitary-thyroid axis in rats. Al-Qarawi AA, Al-Damegh MA, ElMougy SA. Phytother Res. 2002 May;16(3):286-7.
Effects of Eucommia leaf extracts on autonomic nerves, body temperature, lipolysis, food intake, and body weight. Horii Y, Tanida M, Shen J, Hirata T, Kawamura N, Wada A, Nagai K. Neurosci Lett. 2010 Aug 2;479(3):181-6. Epub 2010 May 16.
Chlorogenic Acid and Synthetic Chlorogenic Acid Derivatives:  Novel Inhibitors of Hepatic Glucose-6-phosphate Translocase. Horst Hemmerle, Hans-Joerg Burger, Peter Below, Gerrit Schubert, Robert Rippel, Peter W. Schindler, Erich Paulus, and Andreas W. Herling. J. Med. Chem., 1997, 40 (2), pp 137–145
Role of Glucose-6 Phosphatase, Glucokinase, and Glucose-6 Phosphate in Liver Insulin Resistance and Its Correction by Metformin. Carol Minassian, Sandrine Tarpin,Gilles Mithieux. Biochemical Pharmacology Volume 55, Issue 8, 15 April 1998, Pages 1213–1219.
The Effect of Chlorogenic Acid Enriched Coffee on Glucose Absorption in Healthy Volunteers and Its Effect on Body Mass When Used Long-term in Overweight and Obese People. Thom, E. The Journal of International Medical Research, Volume 35, Number 6, November 2007 , pp. 900-908(9).
Chlorogenic Acid and Caffeic Acid Are Absorbed in Humans. Margreet R. Olthof, Peter C. H. Hollman, and Martijn B. Katan. J. Nutr. January 1, 2001 vol. 131 no. 1 66-71
Park JB. N-coumaroyldopamine and N-caffeoyldopamine increase cAMP via beta 2-adrenoceptors in myelocytic U937 cells. FASEB J. 2005 Apr;19(6):497-502
Kline WO, Panaro FJ, Yang H, et al. Rapamycin inhibits the growth and muscle-sparing effects of clenbuterol. J Apply Physiol. 2007 Feb;102(2):740-747
Goncalves DA, Lira EC, Baviera AM, et al. Mechanisms involved in 3,5-cyclic adenosine monophosphate-mediated inhibition of ubiquitin-proteasome system in skeletal muscle. Endocrinology. 2009 Dec;150(12):5395-53404
Kunkel SD, Suneja M, Ebert SM, et al. mRNA expression signatures of human skeletal muscle atrophy identify a natural compound that increases muscle mass. Cell Metab. 2011 Jun 8;13(6):627-638
Lee NK & MacLean HE. Polyamines, androgens, and skeletal muscle hypertrophy. J Cell Physiol. 2011 Jun;226(6):1453-1460
Anthony J. C., Anthony T. G., Kimball S. R., Vary T. C., Jefferson L. S. Orally administered leucine stimulates protein synthesis in skeletal muscle of postabsorptive rats in association with increased eIF4F formation. J. Nutr. 2000;130:139-145
Tischler M. E., Desautels M., Goldberg A. L. Does leucine, leucyl-tRNA, or some metabolite of leucine regulate protein synthesis and degradation in skeletal and cardiac muscle?. J. Biol. Chem. 1982;257:1613-1621
Kimball S. R., Shantz L. M., Horetsky R. L., Jefferson L. S. Leucine regulates translation of specific mRNAs in L6 myoblasts through mTOR-mediated changes in availability fo eIF4E and phosphorylation of ribosomal protein S6. J. Biol. Chem. 1999;274:11647-1
Buse M. G., Weigand D. A. Studies concerning the specificity of the effect of leucine on the turnover of proteins in muscles of control and diabetic rats. Biochim. Biophys. Acta 1977;475:81-89
The effect of choline supplementation on the level of plasma free fatty acids and beta-hydroxybutyrate during a session of prolonged exercise. Qolizadeh, M. R.; Ebrahim, K.; Rahbar, B.; Karami, E.; Rostamkhany, H.; Musavi, S. H. Annals of Biological Research 2011 Vol. 2 No. 6 pp. 253-260
 
NutraPlanet CS said:
This might not be "experiments" for the overall product, but definitely legit references for each ingredient.....I think when people do the math, even before trying it, it makes sense......I can assure you of this....PES would NOT come out with a crappy product....EVER. I know them too well.

[h=3]Alphamine References:[/h] Berlan M, Galitzky J, Riviere D, et al. Plasma catecholamine levels and lipid mobilization induced by yohimbine in obese and non-obese women. Int J Obes. 1991 May;15(5):305-315
Galitzky J, Taouis M, Berlan M, et al. Alpha 2-antagonist compounds and lipid mobilization: evidence for a lipid mobilizing effect of oral yohimbine in healthy male volunteers. Eur J Clin Invest. 1988 Dec;18(6):587-594
Flechtner-Mors M, Jenkinson CP, Alt A, et al. In vivo alpha(1)-adrenergic lipolytic activity in subcutaneous adipose tissue of obese subjects. J Pharmacol Exp Ther. 2002 Apr;301(1):229-233
Sax L. Yohimbine does not affect fat distribution in men. Int J Obes. 1991 Sep;15(9):561-565
Kucio C, Jonderko K, Piskorska D. Does yohimbine act as a slimming drug? Isr J Med Sci. 1991 Oct;27(10):550-556
Berlin I, Stalla-Bourdillon A, Thuillier Y, et al. Lack of efficacy of yohimbine in the treatment of obesity. J Pharmacol. 1986 Jul-Sep;17(3):343-347
Zahorska-Markiewicz B, Kucio C, et al. Adrenergic control of lipolysis and metabolic responses in obesity. Horm Metab Res. 1986 Oct;18(10):693-697
Perry BD, U'Prichard DC. [3H]rauwolscine (alpha-yohimbine): a specific antagonist radioligand for brain alpha 2-adrenergic receptors. Eur J Pharmacol. 1981 Dec 17;76(4):461-464
Berlan M, Le Verge R, Galitzky J, et al. Alpha 2-adrenoceptor antagonist potencies of two hydroxylated metabolites of yohimbine. Br J Pharmacol. 1993 Apr;108(4):927-932
Chang KC, Lim JK and Park CW (1986) Synthesis of higenamine and its cardiovascular effects in rabbit: Evidence for b-adrenoceptor agonist. Kor J Pharmacol 22:96 -104
A study on the mechanism of the yang-tonic effect of higenamine. Xiang Rong. Yi Ningyu. Xia Zongqin. PHARMACOLOGY AND CLINICS OF CHINESE MATERIA MEDICA. 1994-06
The Chinese Journal of Clinical Pharmacology, 2007-04. Tolerability of higenamine hydrochloride in healthy volunteers. Yan-rong, Fang, Ri-yi,Yan, OUYANG, Meng, Hong-li.
Eur J Nucl Med. 1983;8(6):233-6. Measurement of effects of the Chinese herbal medicine higenamine on left ventricular function using a cardiac probe. Liu XJ, Wagner HN Jr, Tao S. Planta Med 2009; 75(13): 1393-1399. ?2-Adrenoceptor-Mediated Tracheal Relaxation Induced by Higenamine from Nandina domestica Thunberg Muneo Tsukiyama, Takuro Ueki, Yoichi Yasuda, Hiroko Kikuchi, Tatsuhiro Akaishi, Hidenobu Okumura, Kazuho Abe.
CHINESE PHARMACOLOGICAL BULLETIN 1995-02. The pharmacologic action of higenamine on beta-adrenergic receptors in heart of mice. XIANG Rong; XU Jiang-Tao; YI Nin-Yu; XIA Zhong-Qin
Acta Pharmacol Sin 2008 Oct; 29 (10): 1187-1194. Identification of higenamine in Radix Aconiti Lateralis Preparata as a beta2-adrenergic receptor agonist. Gang BAI, Yang YANG, Qian SHI, Ze LIU, Qi ZHANG, Yuan-yuan ZHU
Acta Pharmaceutica Sinica. 1982-09. EFFECTS OF dl-DEMETHYL COCLAURINE ON ?-ADRENERGIC RECEPTORS AND ADENYLATE CYCLASE IN TURKEY ERYTHROCYTE MEMBRANE. FENG Yi-pu, JIA Hong-jun, ZHANG Li-ying and ZENG Gui-yun
An Experimental Study on Adrenergic Effect of Higenamine in Rabbit Cardiovascular System. Nam Su Kim,Chang Yee Hong,Chan Woong Pak,Jung Kyoo Lim. Korean Circ J 1986;16:1-18
Diepvens K, Westerterp KR, Westerterp-Plantenga MS. Obesity and thermogenesis related to the consumption of caffeine, ephedrine, capsaicin, and green tea. Am J Physiol Regul Integr Comp Physiol. 2007 Jan;292(1):R77-85
Bracco D, Ferrarra JM, Arnaud MJ, et al. Effects of caffeine on energy metabolism, heart rate, and methylxanthine metabolism in lean and obese women. Am J Physiol. 1995 Oct;269(4 Pt 1):E671-E678
Dullo AG, Geissler CA, Horton T, et al. Normal caffeine consumption: influence on thermogenesis and daily energy expenditure in lean and postobese human volunteers. Am J Clin Nutr. 1989 Jan;49(1):44-50
Acheson KJ, Gremaud G, Meirim I, et al. Metabolic effects of caffeine in humans: lipid oxidation or futile cycling? Am J Clin Nutr. 2004 Jan;79(1):40-46
Kaplan GB, Greenblatt DJ, Ehrenberg BL, et al. Dose-dependent pharmacokinetics and psychomotor effects of caffeine in humans. J Clin Pharmacol. 1997 Aug;37(8):693-703
Smith A. Effects of caffeine on human behavior. Food Chem Toxicol. 2002 Sep;40(9):1243-1255
Robertson D, Frolich JC, Carr RK, et al. Effects of caffeine on plasma renin activity, catecholamines and blood pressure. N Engl J Med. 1978 Jan 26;298(4):181-186
Oleuropein, a Phenolic Compound in Extra Virgin Olive Oil, Increases Uncoupling Protein 1 Content in Brown Adipose Tissue and Enhances Noradrenaline and Adrenaline Secretions in Rats. Yuriko Oi-KANO, Teruo KAWADA, Tatsuo WATANABE, Fumihiro KOYAMA, Kenichi WATANABE, Reijirou SENBONGI, Kazuo IWAI. Journal of Nutritional Science and Vitaminology Vol. 54 (2008) No. 5 P 363-370
Olive leaf extract attenuates cardiac, hepatic, and metabolic changes in high carbohydrate-, high fat-fed rats. Poudyal H, Campbell F, Brown L. J Nutr. 2010 May;140(5):946-53. Epub 2010 Mar 24.
Effect of freeze dried extract of Olea europaea on the pituitary-thyroid axis in rats. Al-Qarawi AA, Al-Damegh MA, ElMougy SA. Phytother Res. 2002 May;16(3):286-7.
Effects of Eucommia leaf extracts on autonomic nerves, body temperature, lipolysis, food intake, and body weight. Horii Y, Tanida M, Shen J, Hirata T, Kawamura N, Wada A, Nagai K. Neurosci Lett. 2010 Aug 2;479(3):181-6. Epub 2010 May 16.
Chlorogenic Acid and Synthetic Chlorogenic Acid Derivatives: Novel Inhibitors of Hepatic Glucose-6-phosphate Translocase. Horst Hemmerle, Hans-Joerg Burger, Peter Below, Gerrit Schubert, Robert Rippel, Peter W. Schindler, Erich Paulus, and Andreas W. Herling. J. Med. Chem., 1997, 40 (2), pp 137-145
Role of Glucose-6 Phosphatase, Glucokinase, and Glucose-6 Phosphate in Liver Insulin Resistance and Its Correction by Metformin. Carol Minassian, Sandrine Tarpin,Gilles Mithieux. Biochemical Pharmacology Volume 55, Issue 8, 15 April 1998, Pages 1213-1219.
The Effect of Chlorogenic Acid Enriched Coffee on Glucose Absorption in Healthy Volunteers and Its Effect on Body Mass When Used Long-term in Overweight and Obese People. Thom, E. The Journal of International Medical Research, Volume 35, Number 6, November 2007 , pp. 900-908(9).
Chlorogenic Acid and Caffeic Acid Are Absorbed in Humans. Margreet R. Olthof, Peter C. H. Hollman, and Martijn B. Katan. J. Nutr. January 1, 2001 vol. 131 no. 1 66-71
Park JB. N-coumaroyldopamine and N-caffeoyldopamine increase cAMP via beta 2-adrenoceptors in myelocytic U937 cells. FASEB J. 2005 Apr;19(6):497-502
Kline WO, Panaro FJ, Yang H, et al. Rapamycin inhibits the growth and muscle-sparing effects of clenbuterol. J Apply Physiol. 2007 Feb;102(2):740-747
Goncalves DA, Lira EC, Baviera AM, et al. Mechanisms involved in 3,5-cyclic adenosine monophosphate-mediated inhibition of ubiquitin-proteasome system in skeletal muscle. Endocrinology. 2009 Dec;150(12):5395-53404
Kunkel SD, Suneja M, Ebert SM, et al. mRNA expression signatures of human skeletal muscle atrophy identify a natural compound that increases muscle mass. Cell Metab. 2011 Jun 8;13(6):627-638
Lee NK & MacLean HE. Polyamines, androgens, and skeletal muscle hypertrophy. J Cell Physiol. 2011 Jun;226(6):1453-1460
Anthony J. C., Anthony T. G., Kimball S. R., Vary T. C., Jefferson L. S. Orally administered leucine stimulates protein synthesis in skeletal muscle of postabsorptive rats in association with increased eIF4F formation. J. Nutr. 2000;130:139-145
Tischler M. E., Desautels M., Goldberg A. L. Does leucine, leucyl-tRNA, or some metabolite of leucine regulate protein synthesis and degradation in skeletal and cardiac muscle?. J. Biol. Chem. 1982;257:1613-1621
Kimball S. R., Shantz L. M., Horetsky R. L., Jefferson L. S. Leucine regulates translation of specific mRNAs in L6 myoblasts through mTOR-mediated changes in availability fo eIF4E and phosphorylation of ribosomal protein S6. J. Biol. Chem. 1999;274:11647-1
Buse M. G., Weigand D. A. Studies concerning the specificity of the effect of leucine on the turnover of proteins in muscles of control and diabetic rats. Biochim. Biophys. Acta 1977;475:81-89
The effect of choline supplementation on the level of plasma free fatty acids and beta-hydroxybutyrate during a session of prolonged exercise. Qolizadeh, M. R.; Ebrahim, K.; Rahbar, B.; Karami, E.; Rostamkhany, H.; Musavi, S. H. Annals of Biological Research 2011 Vol. 2 No. 6 pp. 253-260
Click to expand...

Yea but does it have a flashy label with cool designs on it?

But seriously PES doesn't need to hype its products the people who try it do all that for them. Rock solid products by these guys
 
Mrpersinality said:
Yea but does it have a flashy label with cool designs on it?

But seriously PES doesn't need to hype its products the people who try it do all that for them. Rock solid products by these guys
Click to expand...

You're exactly right....PES' products are some of the best to ever be introduced to this market....and there has been quite a few products out in this market through the ages I'd say.
 
^^^And my statement above IS actually unbiased too. I say this from years of experience in the industry.^^^
 
NutraPlanet CS said:
^^^And my statement above IS actually unbiased too. I say this from years of experience in the industry.^^^
Click to expand...

I have the same sentiment and that from years of using supps! I'd put PES against any supp company head to head, period.
 
Dewey99 said:
PES makes quality Supps and for only $30 I think I can run my own "experiment".
Click to expand...

Celorza said:
Lol PES is known for NOT overhyping.
Click to expand...

Mrpersinality said:
Yea but does it have a flashy label with cool designs on it?

But seriously PES doesn't need to hype its products the people who try it do all that for them. Rock solid products by these guys
Click to expand...

NutraPlanet CS said:
You're exactly right....PES' products are some of the best to ever be introduced to this market....and there has been quite a few products out in this market through the ages I'd say.
Click to expand...

BoneDaddy said:
I have the same sentiment and that from years of using supps! I'd put PES against any supp company head to head, period.
Click to expand...

Thank you all for the support and putting your faith in us.

Our mission is to create products that are so effective that the customer reviews do the talking. It is a long process hence our product turnover being much slower than some other companies.

I am pleased that you all appreciate our approach and would like to thank you all for recognising how we work. :)

Ben
 
ralfman5 said:
This is over hyped.. Where are the experiments proving this supplement does what it claims?
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NutraPlanet CS said:
This might not be "experiments" for the overall product, but definitely legit references for each ingredient.....I think when people do the math, even before trying it, it makes sense......I can assure you of this....PES would NOT come out with a crappy product....EVER. I know them too well.

Alphamine References:

Berlan M, Galitzky J, Riviere D, et al. Plasma catecholamine levels and lipid mobilization induced by yohimbine in obese and non-obese women. Int J Obes. 1991 May;15(5):305-315
Galitzky J, Taouis M, Berlan M, et al. Alpha 2-antagonist compounds and lipid mobilization: evidence for a lipid mobilizing effect of oral yohimbine in healthy male volunteers. Eur J Clin Invest. 1988 Dec;18(6):587-594
Flechtner-Mors M, Jenkinson CP, Alt A, et al. In vivo alpha(1)-adrenergic lipolytic activity in subcutaneous adipose tissue of obese subjects. J Pharmacol Exp Ther. 2002 Apr;301(1):229-233
Sax L. Yohimbine does not affect fat distribution in men. Int J Obes. 1991 Sep;15(9):561-565
Kucio C, Jonderko K, Piskorska D. Does yohimbine act as a slimming drug? Isr J Med Sci. 1991 Oct;27(10):550-556
Berlin I, Stalla-Bourdillon A, Thuillier Y, et al. Lack of efficacy of yohimbine in the treatment of obesity. J Pharmacol. 1986 Jul-Sep;17(3):343-347
Zahorska-Markiewicz B, Kucio C, et al. Adrenergic control of lipolysis and metabolic responses in obesity. Horm Metab Res. 1986 Oct;18(10):693-697
Perry BD, U’Prichard DC. [3H]rauwolscine (alpha-yohimbine): a specific antagonist radioligand for brain alpha 2-adrenergic receptors. Eur J Pharmacol. 1981 Dec 17;76(4):461-464
Berlan M, Le Verge R, Galitzky J, et al. Alpha 2-adrenoceptor antagonist potencies of two hydroxylated metabolites of yohimbine. Br J Pharmacol. 1993 Apr;108(4):927-932
Chang KC, Lim JK and Park CW (1986) Synthesis of higenamine and its cardiovascular effects in rabbit: Evidence for b-adrenoceptor agonist. Kor J Pharmacol 22:96 –104
A study on the mechanism of the yang-tonic effect of higenamine. Xiang Rong. Yi Ningyu. Xia Zongqin. PHARMACOLOGY AND CLINICS OF CHINESE MATERIA MEDICA. 1994-06
The Chinese Journal of Clinical Pharmacology, 2007-04. Tolerability of higenamine hydrochloride in healthy volunteers. Yan-rong, Fang, Ri-yi,Yan, OUYANG, Meng, Hong-li.
Eur J Nucl Med. 1983;8(6):233-6. Measurement of effects of the Chinese herbal medicine higenamine on left ventricular function using a cardiac probe. Liu XJ, Wagner HN Jr, Tao S. Planta Med 2009; 75(13): 1393-1399. β2-Adrenoceptor-Mediated Tracheal Relaxation Induced by Higenamine from Nandina domestica Thunberg Muneo Tsukiyama, Takuro Ueki, Yoichi Yasuda, Hiroko Kikuchi, Tatsuhiro Akaishi, Hidenobu Okumura, Kazuho Abe.
CHINESE PHARMACOLOGICAL BULLETIN 1995-02. The pharmacologic action of higenamine on beta-adrenergic receptors in heart of mice. XIANG Rong; XU Jiang-Tao; YI Nin-Yu; XIA Zhong-Qin
Acta Pharmacol Sin 2008 Oct; 29 (10): 1187–1194. Identification of higenamine in Radix Aconiti Lateralis Preparata as a beta2-adrenergic receptor agonist. Gang BAI, Yang YANG, Qian SHI, Ze LIU, Qi ZHANG, Yuan-yuan ZHU
Acta Pharmaceutica Sinica. 1982-09. EFFECTS OF dl-DEMETHYL COCLAURINE ON β-ADRENERGIC RECEPTORS AND ADENYLATE CYCLASE IN TURKEY ERYTHROCYTE MEMBRANE. FENG Yi-pu, JIA Hong-jun, ZHANG Li-ying and ZENG Gui-yun
An Experimental Study on Adrenergic Effect of Higenamine in Rabbit Cardiovascular System. Nam Su Kim,Chang Yee Hong,Chan Woong Pak,Jung Kyoo Lim. Korean Circ J 1986;16:1-18
Diepvens K, Westerterp KR, Westerterp-Plantenga MS. Obesity and thermogenesis related to the consumption of caffeine, ephedrine, capsaicin, and green tea. Am J Physiol Regul Integr Comp Physiol. 2007 Jan;292(1):R77-85
Bracco D, Ferrarra JM, Arnaud MJ, et al. Effects of caffeine on energy metabolism, heart rate, and methylxanthine metabolism in lean and obese women. Am J Physiol. 1995 Oct;269(4 Pt 1):E671-E678
Dullo AG, Geissler CA, Horton T, et al. Normal caffeine consumption: influence on thermogenesis and daily energy expenditure in lean and postobese human volunteers. Am J Clin Nutr. 1989 Jan;49(1):44-50
Acheson KJ, Gremaud G, Meirim I, et al. Metabolic effects of caffeine in humans: lipid oxidation or futile cycling? Am J Clin Nutr. 2004 Jan;79(1):40-46
Kaplan GB, Greenblatt DJ, Ehrenberg BL, et al. Dose-dependent pharmacokinetics and psychomotor effects of caffeine in humans. J Clin Pharmacol. 1997 Aug;37(8):693-703
Smith A. Effects of caffeine on human behavior. Food Chem Toxicol. 2002 Sep;40(9):1243-1255
Robertson D, Frolich JC, Carr RK, et al. Effects of caffeine on plasma renin activity, catecholamines and blood pressure. N Engl J Med. 1978 Jan 26;298(4):181-186
Oleuropein, a Phenolic Compound in Extra Virgin Olive Oil, Increases Uncoupling Protein 1 Content in Brown Adipose Tissue and Enhances Noradrenaline and Adrenaline Secretions in Rats. Yuriko Oi-KANO, Teruo KAWADA, Tatsuo WATANABE, Fumihiro KOYAMA, Kenichi WATANABE, Reijirou SENBONGI, Kazuo IWAI. Journal of Nutritional Science and Vitaminology Vol. 54 (2008) No. 5 P 363-370
Olive leaf extract attenuates cardiac, hepatic, and metabolic changes in high carbohydrate-, high fat-fed rats. Poudyal H, Campbell F, Brown L. J Nutr. 2010 May;140(5):946-53. Epub 2010 Mar 24.
Effect of freeze dried extract of Olea europaea on the pituitary-thyroid axis in rats. Al-Qarawi AA, Al-Damegh MA, ElMougy SA. Phytother Res. 2002 May;16(3):286-7.
Effects of Eucommia leaf extracts on autonomic nerves, body temperature, lipolysis, food intake, and body weight. Horii Y, Tanida M, Shen J, Hirata T, Kawamura N, Wada A, Nagai K. Neurosci Lett. 2010 Aug 2;479(3):181-6. Epub 2010 May 16.
Chlorogenic Acid and Synthetic Chlorogenic Acid Derivatives:  Novel Inhibitors of Hepatic Glucose-6-phosphate Translocase. Horst Hemmerle, Hans-Joerg Burger, Peter Below, Gerrit Schubert, Robert Rippel, Peter W. Schindler, Erich Paulus, and Andreas W. Herling. J. Med. Chem., 1997, 40 (2), pp 137–145
Role of Glucose-6 Phosphatase, Glucokinase, and Glucose-6 Phosphate in Liver Insulin Resistance and Its Correction by Metformin. Carol Minassian, Sandrine Tarpin,Gilles Mithieux. Biochemical Pharmacology Volume 55, Issue 8, 15 April 1998, Pages 1213–1219.
The Effect of Chlorogenic Acid Enriched Coffee on Glucose Absorption in Healthy Volunteers and Its Effect on Body Mass When Used Long-term in Overweight and Obese People. Thom, E. The Journal of International Medical Research, Volume 35, Number 6, November 2007 , pp. 900-908(9).
Chlorogenic Acid and Caffeic Acid Are Absorbed in Humans. Margreet R. Olthof, Peter C. H. Hollman, and Martijn B. Katan. J. Nutr. January 1, 2001 vol. 131 no. 1 66-71
Park JB. N-coumaroyldopamine and N-caffeoyldopamine increase cAMP via beta 2-adrenoceptors in myelocytic U937 cells. FASEB J. 2005 Apr;19(6):497-502
Kline WO, Panaro FJ, Yang H, et al. Rapamycin inhibits the growth and muscle-sparing effects of clenbuterol. J Apply Physiol. 2007 Feb;102(2):740-747
Goncalves DA, Lira EC, Baviera AM, et al. Mechanisms involved in 3,5-cyclic adenosine monophosphate-mediated inhibition of ubiquitin-proteasome system in skeletal muscle. Endocrinology. 2009 Dec;150(12):5395-53404
Kunkel SD, Suneja M, Ebert SM, et al. mRNA expression signatures of human skeletal muscle atrophy identify a natural compound that increases muscle mass. Cell Metab. 2011 Jun 8;13(6):627-638
Lee NK & MacLean HE. Polyamines, androgens, and skeletal muscle hypertrophy. J Cell Physiol. 2011 Jun;226(6):1453-1460
Anthony J. C., Anthony T. G., Kimball S. R., Vary T. C., Jefferson L. S. Orally administered leucine stimulates protein synthesis in skeletal muscle of postabsorptive rats in association with increased eIF4F formation. J. Nutr. 2000;130:139-145
Tischler M. E., Desautels M., Goldberg A. L. Does leucine, leucyl-tRNA, or some metabolite of leucine regulate protein synthesis and degradation in skeletal and cardiac muscle?. J. Biol. Chem. 1982;257:1613-1621
Kimball S. R., Shantz L. M., Horetsky R. L., Jefferson L. S. Leucine regulates translation of specific mRNAs in L6 myoblasts through mTOR-mediated changes in availability fo eIF4E and phosphorylation of ribosomal protein S6. J. Biol. Chem. 1999;274:11647-1
Buse M. G., Weigand D. A. Studies concerning the specificity of the effect of leucine on the turnover of proteins in muscles of control and diabetic rats. Biochim. Biophys. Acta 1977;475:81-89
The effect of choline supplementation on the level of plasma free fatty acids and beta-hydroxybutyrate during a session of prolonged exercise. Qolizadeh, M. R.; Ebrahim, K.; Rahbar, B.; Karami, E.; Rostamkhany, H.; Musavi, S. H. Annals of Biological Research 2011 Vol. 2 No. 6 pp. 253-260
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You should read ALL of them on your lunch break :)
 
BoneDaddy said:
Wait until the logs pop up.....bet you wont hear a peep from this troll.
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I enjoy PES logs a lot, PES never has to resort to desperate measures as to giving a huge amount of free products just to spam the Supp Review page with logs of their products. Some of PES's logs are even done un-sponsored and that just goes to show you cannot buy the consumers satisfaction, if your product is good then it will shine...if it isn't, well even if you give it out for free results are gonna show the quality of it.

Anyhow, I am sure the Alphamine logs will be quite fun to follow :) (and I am willing to bet they will reflect what 99% of the other PES logs show, that it is a proven effective supp)
 
Celorza said:
I enjoy PES logs a lot, PES never has to resort to desperate measures as to giving a huge amount of free products just to spam the Supp Review page with logs of their products. Some of PES's logs are even done un-sponsored and that just goes to show you cannot buy the consumers satisfaction, if your product is good then it will shine...if it isn't, well even if you give it out for free results are gonna show the quality of it.

Anyhow, I am sure the Alphamine logs will be quite fun to follow :) (and I am willing to bet they will reflect what 99% of the other PES logs show, that it is a proven effective supp)
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You are right that PES doesn't have to give away a ton of free products. That being said, I am cool if they want to send some my way.....:thumbsup:
 
There was me thinking we were very generous with how many supplements we give to customers for free!
 
bdcc said:
There was me thinking we were very generous with how many supplements we give to customers for free!
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I got Alphamine, AE and EP all for a ridiculous price through that Insider's Sale last week. Guess that was kind of like a giveaway since all three together cost me about what a bottle of EP goes for. Still willing to take some more free stuff is PES needs people to "experiment" on!
 
bdcc said:
There was me thinking we were very generous with how many supplements we give to customers for free!
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Hahaha one thing is Natty's love and giving away free products. And another is the fact of going ahead and starting giving products in exchange for logs just because a new fat burner came to town brother :). We all know PES is generous and is a Consumer-First company. What I meant to say is you don't rely on buying the love of the community, you guys earn it with amazing formulas and innovation. The same way you guys never need to over-hype a product or start announcing it long before its release making promises of its success :D!. You let it speak for itself ;)!
 
bdcc said:
There was me thinking we were very generous with how many supplements we give to customers for free!
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I just get annoyed when you give products that could go to me to other people. You give a lot of supplements to customers for free, but every time you do I just get annoyed thinking how that's another product that could have went to me ;)
 
I didn't mean it like that!! I just want to know for instance comparing two people with similar physiology, and on a caloric deficit , doing cardio . One taking this supplement and the other no supplement. How much more fat in pounds will the person taking this supplement lose? I'm sure u guys tested this supplement before releasing it to the public.
 
ralfman5 said:
I didn't mean it like that!! I just want to know for instance comparing two people with similar physiology, and on a caloric deficit , doing cardio . One taking this supplement and the other no supplement. How much more fat in pounds will the person taking this supplement lose? I'm sure u guys tested this supplement before releasing it to the public.
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When I would like to know how a supplement works, I used it myself. Everyone will react differently to each supplement, so I am saying is be your own guinea pig. As for PES supps. Thank you for making quality products that work, don't need no logs or reviews to know it works, because I use all of your supps. With great results. :))
 
so has this been released yet?
 
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