thesinner
Recovering AXoholic
VC/PS work through more indirect mechanisms.
The research on 7-keto has shown it to increase free test, but lower total test. Oral dosage shouldn't be much of an issue, since they go right into the liver, where they are locally metabolized. The "lowering steroidogenesis" you are referring to is that 11-HSD is contained in a local concentration near the testes, where LH production is released, and partway controlled by cortisone levels.
The research on 7-keto has shown it to increase free test, but lower total test. Oral dosage shouldn't be much of an issue, since they go right into the liver, where they are locally metabolized. The "lowering steroidogenesis" you are referring to is that 11-HSD is contained in a local concentration near the testes, where LH production is released, and partway controlled by cortisone levels.