It includes well-dosed St. John's Wort, and 5-HTP, and the herb that's in Zembrin and SNS's KannaEase. That combination (mostly the St. John's) creates some risk of serotonin syndrome. Including Mucuma Pruriens with St. John's is a sketchy decision also because the latter also works as a dopamine reuptake inhibitor (although could also feel great lol). I think it's flat out unethical to include St. John's in a multi-ingredient product of any kind but that combination is so powerful it could be risky. St. John's also interacts with a ton of prescription meds via increasing enzyme activity and I think there's a good argument for it being more regulated (as it is in some European countries).
I'm really looking forward to mood support xt, not knowing already what's in it, because I think Steve has a lot better sense.
This isn't meant as negative towards them, I'm just talking about the ingredients and the combinations thereof.
I would like to compliment you for pointing out some very legitimate facts about that formula.
When I first saw that formula, I couldn't help but wonder if any actual method of action thought was put into that product or if someone just looked up popular ingredients for mood and threw them together without researching anything about the way they work or interactions.
There are multiple things in there that should never be mixed with St. John's Wort.
Drugs.com literally has a warning page about not mixing St. Johns Wort and 5-HTP together.
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Then an argument could be made, like you said, about not mixing St. John's Wort with Mucuna; and I could also make an argument to not mix St. John's Wort with SAM-e too.
Yet, that product mixes all 4 of them together in one product.
I absolutely agree with you that St. John's Wort is best to be a single ingredient product - it can be good for some people, but its best left to being a single ingredient product so that people can experiment with it by itself if they want to. It is also extremely important to use a form std. to .3% Hypericin and from a reputable company. If someone wants to try it, I would strongly suggest NOW Foods brand. (I don't suggest trying it, but if you're going to, that's the one I would suggest).
In addition to the Hypericin content of the St. John's Wort not being shown, they don't show the Kavalactone content of the Kava and does not list the any of the warnings that are customary with a Kava based product.
They also do not show the standardization of the Kanna. Branded versions make you state so on the label, and if its a non-branded extract then there's no information on it listed at all. 50 mg. is a great dose for KannaEase, but would be trivial for generic Kanna Extract.
I think that 99.9% of the time, the discussion of the risk of Serotonin syndrome with supplements is people being paranoid and overly dramatic - in my opinion, this is that .01% of time where it is a very legitimate worry.