Type 1 aromatase inhibitor

[Jackedjack]

What exactly does a suicidal inhibitor do. I know it binds to the aromatase enzyme irreversibly, but when you go off of it, does it just effect the enzymes it has already bound to. Because like proteins, which enzymes are essentially, they can be made again and again. So after stoppage of the ai will new aromatase produced be stopped? Sorry for the wording of this exams do this to you.

 

[mr.cooper69]

A suicidal inhibitor deactives the enzyme for its lifetime in the body. Regeneration of the enzyme supply is based on turnover rates. So a suicidal AI takes longer to kick in (several weeks), and just as long to stop working after ceasing consumption, since production of aromatase will be dependent on enzyme turnover

 

[Jackedjack]

A suicidal inhibitor deactives the enzyme for its lifetime in the body. Regeneration of the enzyme supply is based on turnover rates. So a suicidal AI takes longer to kick in (several weeks), and just as long to stop working after ceasing consumption, since production of aromatase will be dependent on enzyme turnover

Never cease to amaze me coop