Transdermal PDE5 Inhibitors

[MAxximal]

Hi


Is Possible make a like:

Tadalafil Citrate(Cialis)
Sildenafil itrate (Viagra)
Vardenafil (Levitra)

maybe is not a good idea but i like to know.

 

[Rodja]

Any reason for doing that?

 

[MAxximal]

Any reason for doing that?

no Rod only a question around my mind what do you think?

 

[Rodja]

The MW is kinda high and they work orally. Seems pointless.

 

[MAxximal]

hmmmmmmm

 

[DAdams91982]

No, all of them have a high molecular weight, higher than warranted for trans-dermal. Cialis is close, but still to high.

Just go the the penis shot.... let us know how that works out for you.

 

[MAxximal]

what is the MW?

a TD formula of this enter in your bloodstream much faster than digesting a pill right?

 

[Rodja]

what is the MW?

a TD formula of this enter in your bloodstream much faster than digesting a pill right?

In theory, but it's pointless. The lowest MW is ~390 for Cialis.

I think you're missing the point of a transdermal. They're used when the oral availability is low. These drugs are definitely potent.

 

[DAdams91982]

Rodja is right. You will only gain at the top end 25% product absorbtion, whilst oral is much higher than that for these products. It is much slower to enter the blood stream actually, with a slower release of upward of 12 hours. You want bang for these products, so oral is the way to go. Plus, slathering yourself up with PDE5 inhibitors then going for a naked roll in the sheets with your lady friend may not be a good idea due to transfer.

 

[MAxximal]

yeap i understand guys!