ThatGuyZA
Member
Just a side note on the Proviron addition for those interested !
Proviron (Mesterolone) - is a relatively weak anabolic agent generally used in hormone replacement therapy.
When used on its own Proviron doesn't lead to large muscle gains. Where it does play a significant role, is that it binds as much as 60-65% to the Sex- Hormone Binding Globulin (SHBG). This may act to displace other steroids more weakly bound to SHBG into a free (active) state. SHBG binds to testosterone very strongly and about 95-99% of your testosterone is connected to it. Only the free fraction of circulating testosterone is actually what is making you grow.
In simpler terms, Proviron’s ability to connect so strongly to SHBG will free up other steroids in your stack to allow them to exercise more activity.
Proviron also binds to the aromatase enzymes, preventing them from converting your other steroid compounds to estrogen. This gives Proviron the added benefit of acting as a moderately effective anti-estrogen. Thanks to this, Proviron has no estrogenic side-effects making it a very welcome addition to any pre-contest cycle.
Another advantage is that Proviron is not c-17 alpha alkylated. Instead it was modified with the addition of a methyl group at carbon one, which helps protect the hormone from hepatic metabolism during oral administration. This is a characteristic shared with oral Primobolan. Since it’s not c-17 alpha alkylated liver toxicity is non-existent and thus Proviron is considered one of the safest steroids out there.
Proviron (Mesterolone) - is a relatively weak anabolic agent generally used in hormone replacement therapy.
When used on its own Proviron doesn't lead to large muscle gains. Where it does play a significant role, is that it binds as much as 60-65% to the Sex- Hormone Binding Globulin (SHBG). This may act to displace other steroids more weakly bound to SHBG into a free (active) state. SHBG binds to testosterone very strongly and about 95-99% of your testosterone is connected to it. Only the free fraction of circulating testosterone is actually what is making you grow.
In simpler terms, Proviron’s ability to connect so strongly to SHBG will free up other steroids in your stack to allow them to exercise more activity.
Proviron also binds to the aromatase enzymes, preventing them from converting your other steroid compounds to estrogen. This gives Proviron the added benefit of acting as a moderately effective anti-estrogen. Thanks to this, Proviron has no estrogenic side-effects making it a very welcome addition to any pre-contest cycle.
Another advantage is that Proviron is not c-17 alpha alkylated. Instead it was modified with the addition of a methyl group at carbon one, which helps protect the hormone from hepatic metabolism during oral administration. This is a characteristic shared with oral Primobolan. Since it’s not c-17 alpha alkylated liver toxicity is non-existent and thus Proviron is considered one of the safest steroids out there.