SUPERDROL/MSTEN 2A/2 METHYLATION?

[skull]

.could someone explain the difference between superdrol 2a methyl and msten 2methyl [planer?] and how. or if it has to do anything with AR binding?

 

[skull]

.could someone explain the difference between superdrol 2a methyl and msten 2methyl [planer?] and how. or if it has to do anything with AR binding?

I read somewhere .that SD doesn't bind to AR very well [it uses progestin receptor to get to .AR] .and thats how you can get gyno after cycle--so is MSTEN any better?

 

[g0hardorgohom]

SD seems to give gyno for some users more often than M-Sten but I'm not sure if it really does it because of PR receptors.

SD is more effective muscle builder mg/mg though... But M-Sten is potent compound as well!

 

[jbryand101b]

I'm all hoped up on Nyquil right now an can't think straight. But the first answer isnt right.

 

[skull]

I'm all hoped up on Nyquil right now an can't think straight. But the first answer isnt right.

.so SD binds AR directly/?.and what about the term[ planer-from .msten profile?] does it just mean flatter-better fit AR?------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------this is the article -------Because superdrol is androgenic, but lacks the ability to show affinity via 5ar, it circulates, and this causes the large amounts of androgens to look for a transporter, so that it can bind to the androgen recptor, so it uses prolactin wich has a high affinity to cytoplasmic receptor protein, allowing the androgens, testosterone, to be carried and allowing them to convert to dht, only problem is prolactin hormone or luteotropic hormone is synthesised and secreted by sex binding lactotrope cells in the adenohypophysis (anterior pituitary gland, And this gland now produces more prolactin to help deal with the large amount of testosterone circulating that hasnt bound to the estrogen of androgen receptor, Part of the reason why superdol is so anabolic, So instead of binding to the androgen receptors in the scalp and the prostrate it converts to dht through this unique process, using prolactin to enter the cytoplasmic receptror protein, and allowing it to convert to dht and then bind to the androgen receptors in the muscle, causing its distinct hardening effects, it still cant bind to the scalp or prostrate via 5ar as the form of dht it has converted too doesnt allow for that affinity.
So more prolactin is produced to allow for the superdol to find a receptor ,this excess prolactin triggers a process that fills the breast with milk via a process called lactogenesis, in men however it causes a distinct enlargment of the mammary gland and can even cause a man to lactate.

If superdrol had better binding to the androgen receptor via 5AR then this problem would be prevented, the other thing is that prolactin production can remain elevated for months after a cycle has finished, and once the androgen has been removed, ( the cycle is over) the cytoplasmic receptor proteins have nothing to do other than to allow the prolactin to proceed with its hormonal action within the body, causing the male mammary gland to enlarge ready to produce milk... Hence the REBOUND gyno, this is why proper pct is needed for superdrol, and the use of something to prevent prolactin.

 

[jbryand101b]

See the first thing that shows the article is full of shiit is the fact that Superdrol doesn't bind with 5alpha reductase enzyme.

You know why? Because its already 5alpha reduced.

Superdrol= di methyl DHT

 

[skull]

See the first thing that shows the article is full of shiit is the fact that Superdrol doesn't bind with 5alpha reductase enzyme.

You know why? Because its already 5alpha reduced.

Superdrol= di methyl DHT

----------------------------------------------------------------------------------------------------------------------------------------------------------------------..so the art is BS -OK--what does the Msten being a [planer-in profile].all about

 

[jbryand101b]

im not sure I understand what you are asking?

to see how the addition of 2 methylation changes the compound, just compare it with methyl 1-testosterone.

 

[reps4jesus]

Why do you keep--------------------------------------doing this. Stahhhhp.