great thready guys. So it seems that without health insurance, a rough program would be: 1) HCG + AI (arimidex or letrozole) first to restore leydig cell/testicle function, followed by
2) clomid w/ or w/out Novaldex after to ramp up LH
would that be a suitable program?
There is evidence that ALCAR, Zinc, selenium, NAC, ginger, omega 3 fats etc can also help, and perhaps products like Toco 8 as well.
In a new double-blind, placebo-controlled, randomized study, selenium and N-acetyl cysteine (NAC) improved fertility in men.
The study included 468 infertile men who had poor sperm quality. The men (116 subjects) were randomized to receive 200 mcg selenium orally per day, 600 mg N-acetyl-cysteine orally per day (118 subjects), 200 mcg selenium plus 600 mg N-acetyl-cysteine orally daily (116 subjects) or a placebo (118 subjects). The subjects were given the supplements for 26 weeks, followed by a 30-week treatment-free period, and provided blood samples for the measurement of serum testosterone, estradiol, follicle-stimulating hormone (FSH), luteinizing hormone, prolactin, inhibin B (a hormone that inhibits FSH production), selenium and N-acetyl-cysteine. FSH regulates the development, growth, pubertal maturation, and reproductive processes of the human body. In males FSH is critical in spermatogenesis. Luteinizing hormone (LH) also is essential for reproduction in males. LH acts upon the Leydig cells of the testis to trigger the production of testosterone, which in turns helps produce spermatogenesis.
In addition to measuring the above factors, researchers obtained semen samples from the subjects for routine semen analysis, and the measurement of seminal plasma selenium and N-acetyl-cysteine. In analyzing these samples, the scientists discovered that selenium and N-acetyl-cysteine appeared to balance the levels of serum follicle-stimulating hormone, serum testosterone and inhibin B. All semen parameters significantly improved with selenium and N-acetyl-cysteine treatment. Administering selenium plus N-acetyl-cysteine resulted in additive beneficial effects. A strong correlation was observed between the administration of combined selenium and N-acetyl-cysteine and mean sperm concentration, sperm motility and percent of the sperm that had normal structure and form.
According to the researchers, “These results indicate that supplemental selenium and N-acetyl-cysteine improve semen quality. We advocate their use for male infertility treatment.”
The effects of Ginger on spermatogenesis and sperm parameters of rat
Khaki, Arash; Fathiazad, Fatemeh; Nouri, Mohammad; Khaki, Amir Afshin; Ozanci, Chelar C; Ghafari-Novin, Marefat & Hamadeh, Mohammad
Abstract
Background: Ginger rhizome (Zingiber officinale R., family: Zingiberaceae) is used medicinally and as a culinary spice.
Objective: Medicinal use of ginger dates back to ancient China and India. Ginger and its constituents are stated to have antiemetic, antithrombotic, antihepatotoxic, anti-inflammatory, stimulant, cholagogue and antioxidant. It has been used since ancient time as medicinal and food origins it contain antioxidative and androgenic activities and have well effect in diseases treatment in more countries world-wide. As an antioxidant’s ginger has a useful effect on spermatogenesis and sperm parameters.
Materials and Methods: Wistar male rat (n=30) were allocated into three groups, control (n=10) and test groups (n=20), that subdivided into groups of 2 that received ginger rhizome powder (50 and 100mg/kg/day) for 20 consequence day. Animals were kept in standard conditions. In twentieth day the testes tissue of Rats in whole groups were removed and sperm was collected from epididymis and prepared for analysis. Results: Serum total testosterones significantly increased in experimental group that has received 100 mg/kg/day Ginger (p<0.05) in comparison to control group. Besides, the percentage of sperm viability and motility in both test groups significantly increased (p<0.05) in comparison to control group, Whereas, LH, FSH hormones, sperm concentration, morphology and testes weights in both experimental and control group were similar.
Conclusion: Results revealed that administration of 100 mg/kg/day of ginger significantly increased sperm percentage, viability, motility and serum total testosterones. This suggested that ginger may be promising in enhancing sperm healthy parameters.
