After Anavar is taken, and its active in the system, its up regulation on the androgen receptor and its ability to cause Noradrenalin to bind to adrenoreceptors in fat cells, then Guanine nucleotide proteins cause the enzyme Adenylate cyclase to convert ATP into cAMP. (This is why creatine and Anavar work so well together as creatine increases muscle ATP)
cAMP then binds to the protein kinase A, then protein kinase A release its catalytic subunit, This subunit phosphorylates (HSL ) it then becomes an active enzyme, called HSL-P, Then finally a 3 step action catalytic action takes place wich causes the breakdown of tryglycerides, they are then released into the blood system and excreted.
The body tries to prevent fat breakdown via the negative feedback loop. One way it does this with Anavar is to try and prevent the accumulation of cAMP within cells. Caffeine can be used to prevent this by inhibiting phosphodiesterases within the cell. It also can prevent the actions of adenosine, which make it very useful when used along side Anavar at a dose of 60mg-90 mg, pre workout.