I know I said high dose NSAIDs have been linked to impacted muscle growth/repair, as referenced above by others, so I am have always kept anything anti-inflammatory away from training out of an abundance of caution. BUT I just came across this abstract on Curcumin and think it’s too awesome not to share:
Immobilization is characterized by activation of the ubiquitin (Ub)-proteasome-dependent proteolytic system (UPS) and of the mitochondrial apoptotic pathway. Increased oxidative stress and inflammatory response occur in immobilized skeletal muscles. Curcumin exhibits antioxidant and...
pubmed.ncbi.nlm.nih.gov
^In this 2012 RAT STUDY, they bound hind legs of rats for 8 days, then released the legs to recover/regrow for the next 10 days. They injected half the rats with Curcumin throughout the 18 days, and the other half with placebo.
Muscle atrophy was similar at the 8 day mark for all rats, but after the 10 additional recovery days, the rats who had been injected with Curcumin the entire throughout the 18 day total showed bigger, better recovered legs.
Taking Curcumin during the period of catabolism (like training would be) and post promoted superior muscle regrowth.
Maybe I will experiment with periWO administration going forward!